Role of interleukins in the regulation of basophil development and secretion

Current Opinion in Hematology

Volumn 17, Issue 1, 2010, Pages 60-66

  Valent, Peter ^a,b   Dahinden, Clemens A ^c  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

Allergy; Basophils; Cytokines; Histamine; Immunoglobulin E; Interleukin 3; Interleukin 33

Indexed keywords

CHEMOKINE; CYTOKINE; EOTAXIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; INTERLEUKIN 33; INTERLEUKIN 5; INTERLEUKIN 8;

BASOPHIL; CELL DIFFERENTIATION; CELL GROWTH; HUMAN; LEUKOCYTE ADHERENCE; LEUKOCYTE MIGRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW;

ANIMALS; BASOPHILS; CELL ADHESION; CELL MOVEMENT; HUMANS; INTERLEUKINS; MYELOID PROGENITOR CELLS;

EID: 73849142483     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e328331fae9     Document Type: Review

References (68)

1. Valent P, Bettelheim P. The human basophil. Crit Rev Oncol Hematol 1990; 10:327-352.
2. Dvorak AM. Cell biology of the basophil. Int Rev Cytol 1998; 180:87-236.
3. Falcone FH, Haas H, Gibbs BF. The human basophil: a new appreciation of its role in immune responses. Blood 2000; 96:4028-4038.
4. Schroeder JT. Basophils beyond effector cells of allergic inflammation. Adv Immunol 2009; 101:123-161.
5. Marone G, Spadaro G, Patella V, Genovese A. The clinical relevance of basophil releasability. J Allergy Clin Immunol 1994; 94:1293-1303.
6. MacGlashan DW. Relationship between spleen tyrosine kinase and phosphatidylinositol 5' phosphatase expression and secretion from human basophils in the general population. J Allergy Clin Immunol 2007; 119:626-633.
7. Youssef LA, Schuyler M, Gilmartin L, et al. Histamine release fromthe basophils of control and asthmatic subjects and a comparison of gene expression between 'releaser' and 'nonreleaser' basophils. J Immunol 2007; 178: 4584-4594.
8. Lourenço FD, Azor MH, Santos JC, et al. Activated status of basophils in chronic urticaria leads to interleukin-3 hyper-responsiveness and enhancement of histamine release induced by anti-IgE stimulus. Br J Dermatol 2008; 158:979-986.
9. Denburg JA, Richardson M, Telizyn S, Bienenstock J. Basophil/mast cell precursors in human peripheral blood. Blood 1983; 61:775-780.
10. Leary AG, Ogawa M. Identification of pure and mixed basophil colonies in culture of human peripheral blood and marrow cells. Blood 1984; 64:78-83.
11. Arock M, Schneider E, Boissan M, et al. Differentiation of human basophils: an overview of recent advances and pending questions. J Leukoc Biol 2002; 71:557-564.
12. Sillaber C, Geissler K, Scherrer R, et al. Type beta transforming growth factors promote interleukin-3 (IL-3)-dependent differentiation of human basophils but inhibit IL-3-dependent differentiation of human eosinophils. Blood 1992; 80:634-641.
13. Agis H, Willheim M, Sperr WR, et al. Monocytes do not make mast cells when cultured in the presence of SCF. Characterization of the circulating mast cell progenitor as a c-kit+, CD34+, Ly-, CD14-, CD17-, colony-forming cell. J Immunol 1993; 151:4221-4227.
14. Chen CC, Grimbaldeston MA, Tsai M, et al. Identification of mast cell progenitors in adult mice. Proc Natl Acad Sci U S A 2005; 102:11408-11413.
15. Mukai K, Matsuoka K, Taya C, et al. Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells. Immunity 2005; 23:191-202.
16. Kocabas CN, Yavuz AS, Lipsky PE, et al. Analysis of the lineage relationship between mast cells and basophils using the c-kit D816V mutation as a biologic signature. J Allergy Clin Immunol 2005; 115:1155-1161.
17. Valent P, Ashman LK, Hinterberger W, et al. Mast cell typing: demonstration of a distinct hematopoietic cell type and evidence for immunophenotypic relationship to mononuclear phagocytes. Blood 1989; 73:1778-1785.
18. Agis H, Fü reder W, Bankl HC, et al. Comparative immunophenotypic analysis of human mast cells, blood basophils and monocytes. Immunology 1996; 87:535-543.
19. Saito H, Matsumoto K, Okumura S, et al. Gene expression profiling of human mast cell subtypes: an in silico study. Allergol Int 2006; 55:173-179.
20. Saito H, Hatake K, Dvorak AM, et al. Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins. Proc Natl Acad Sci U S A 1988; 85:2288-2292.
21. Valent P, Schmidt G, Besemer J, et al. Interleukin-3 is a differentiation factor for human basophils. Blood 1989; 73:1763-1769.
22. Denburg JA, Silver JE, Abrams JS. Interleukin-5 is a human basophilopoietin: induction of histamine content and basophilic differentiation of HL-60 cells and of peripheral blood basophil-eosinophil progenitors. Blood 1991; 77:1462-1468.
23. Valent P, Besemer J, Muhm M, et al. Interleukin 3 activates human blood basophils via high-affinity binding sites. Proc Natl Acad Sci U S A 1989; 86:5542-5546.
24. Lopez AF, Eglinton JM, Lyons AB, et al. Human interleukin-3 inhibits the binding of granulocyte-macrophage colony-stimulating factor and interleukin-5 to basophils and strongly enhances their functional activity. J Cell Physiol 1990; 145:69-77.
25. Lopez AF, Lyons AB, Eglinton JM, et al. Specific binding of human interleukin-3 and granulocyte-macrophage colony-stimulating factor to human basophils. J Allergy Clin Immunol 1990; 85:99-102.
26. Mayer P, Valent P, Schmidt G, et al. The in vivo effects of recombinant human interleukin-3: demonstration of basophil differentiation factor, histamine-producing activity, and priming of GM-CSF-responsive progenitors in nonhuman primates. Blood 1989; 74:613-621.
27. Ohmori K, Luo Y, Jia Y, et al. IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleen. J Immunol 2009; 182:2835-2841.
28. Tsuda T, Wong D, Dolovich J, et al. Synergistic effects of nerve growth factor and granulocyte-macrophage colony-stimulating factor on human basophilic cell differentiation. Blood 1991; 77:971-979.
29. Schroeder JT, Chichester KL, Bieneman AP. Human basophils secrete IL-3: evidence of autocrine priming for phenotypic and functional responses in allergic disease. J Immunol 2009; 182:2432-2438.
30. Bosma TJ, Kennedy MA, Bodger MP, et al. Basophils exhibit rearrangement of the bcr gene in Philadelphia chromosome-positive chronic myeloid leukemia. Leukemia 1988; 2:141-143.
31. Bodger MP, Morris CM, Kennedy MA, et al. Basophils (Bsp-1+) derive from the leukemic clone in human myeloid leukemias involving the chromosome breakpoint 9q34. Blood 1989; 73:777-781.
32. Aichberger KJ, Mayerhofer M, Vales A, et al. The CML-related oncoprotein BCR/ABL induces expression of histidine decarboxylase (HDC) and the synthesis of histamine in leukemic cells. Blood 2006; 108:3538-3547.
33. Dahinden CA, Kurimoto Y, De Weck AL, et al. The neutrophil-activating peptide NAF/NAP-1 induces histamine and leukotriene release by interleukin 3-primed basophils. J Exp Med 1989; 170:1787-1792.
34. Haak-Frendscho M, Arai N, Arai K, et al. Human recombinant granulocytemacrophage colony-stimulating factor and interleukin 3 cause basophil histamine release. J Clin Invest 1988; 82:17-20.
35. Hirai K, Morita Y, Misaki Y, et al. Modulation of human basophil histamine release by hemopoietic growth factors. J Immunol 1988; 141:3958-3964.
36. Bischoff SC, de Weck AL, Dahinden CA. Interleukin 3 and granulocyte/ macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a. Proc Natl Acad Sci U S A 1990; 87:6813-6817.
37. Bischoff SC, Brunner T, De Weck AL, Dahinden CA. Interleukin 5 modifies histamine release and leukotriene generation by human basophils in response to diverse agonists. J Exp Med 1990; 172:1577-1582.
38. Kurimoto Y, De Weck AL, Dahinden CA. The effect of interleukin 3 upon IgEdependent and IgE-independent basophil degranulation and leukotriene generation. Eur J Immunol 1991; 21:361-368.
39. Krieger M, Brunner T, Bischoff SC, et al. Activation of human basophils through the IL-8 receptor. J Immunol 1992; 149:2662-2667.
40. Kuna P, Reddigari SR, Rucinski D, et al. Monocyte chemotactic and activating factor is a potent histamine-releasing factor for human basophils. J Exp Med 1992; 175:489-493.
41. Dahinden CA, Krieger M, Brunner T, Bischoff SC. Basophil activation by members of the chemokine superfamily. Adv Exp Med Biol 1993; 351:99-110.
42. Kaplan AP, Kuna P, Reddigari SR. Chemokines as allergic mediators: relationship to histamine-releasing factors. Allergy 1994; 49:495-501.
43. Dahinden CA, Geiser T, Brunner T, et al. Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine. J Exp Med 1994; 179:751-756.
44. Weber M, Uguccioni M, Ochensberger B, et al. Monocyte chemotactic protein MCP-2 activates human basophil and eosinophil leukocytes similar to MCP-3. J Immunol 1995; 154:4166-4172.
45. Forssmann U, Uguccioni M, Loetscher P, et al. Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes. J Exp Med 1997; 185:2171-2176.
46. Bischoff SC, Krieger M, Brunner T, et al. RANTES and related chemokines activate human basophil granulocytes through different G protein-coupled receptors. Eur J Immunol 1993; 23:761-767.
47. Uguccioni M, Mackay CR, Ochensberger B, et al. High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. J Clin Invest 1997; 100:1137-1143.
48. Pecaric-Petkovic T, Didichenko SA, Kaempfer S, et al. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL- 33. Blood 2009; 113:1526-1534.
49. Suzukawa M, Iikura M, Koketsu R, et al. An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol 2008; 181:5981-5989.
50. Smithgall MD, Comeau MR, Yoon BR, et al. IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK cells. Int Immunol 2008; 20:1019-1030.
51. Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005; 23:479-490.
52. Dinarello CA. An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor. Immunity 2005; 23:461-462.
53. Iikura M, Suto H, Kajiwara N, et al. IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab Invest 2007; 87:971-978.
54. Moulin D, Donzé O, Talabot-Ayer D, et al. Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells. Cytokine 2007; 40:216-225.
55. Cherry WB, Yoon J, Bartemes KR, et al. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J Allergy Clin Immunol 2008; 121: 1484-1490.
56. Suzukawa M, Koketsu R, Iikura M, et al. Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils. Lab Invest 2008; 88:1245-1253.
57. Valent P, Bettelheim P. Cell surface structures on human basophils and mast cells: biochemical and functional characterization. Adv Immunol 1992; 52:333-423.
58. Florian S, Sonneck K, Czerny M, et al. Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies. Allergy 2006; 61:1054-1062.
59. Yoshimoto T, Tsutsui H, Tominaga K, et al. IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils. Proc Natl Acad Sci U S A 1999; 96:13962-13966.
60. Yoshimoto T, Nakanishi K. Roles of IL-18 in basophils and mast cells. Allergol Int 2006; 55:105-113.
61. Sha Q, Poulsen LK, Gerwien J, et al. Signaling transduction pathways involved in basophil adhesion and histamine release. Chin Med J 2006; 119:122-130.
62. Gibbs BF, Rä thling A, Zillikens D, et al. Initial Fc epsilon RI-mediated signal strength plays a key role in regulating basophil signaling and deactivation. J Allergy Clin Immunol 2006; 118:1060-1067.
63. MacGlashan D. IgE receptor and signal transduction in mast cells and basophils. Curr Opin Immunol 2008; 20:717-723.
64. Hida S, Yamasaki S, Sakamoto Y, et al. Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol 2009; 10:214-222.
65. Tschopp CM, Spiegl N, Didichenko S, et al. Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma. Blood 2006; 108:2290-2299.
66. Didichenko SA, Spiegl N, Brunner T, Dahinden CA. IL-3 induces a Pim1- dependent antiapoptotic pathway in primary human basophils. Blood 2008; 112:3949-3958.
67. Spiegl N, Didichenko S, McCaffery P, et al. Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid. Blood 2008; 112:3762-3771.
68. Valent P, Besemer J, Sillaber C, et al. Failure to detect IL-3-binding sites on human mast cells. J Immunol 1990; 145:3432-3437.