Association of mitochondrial allele 4216c with increased risk for sepsis-related organ dysfunction and shock after burn injury

Shock

Volumn 33, Issue 1, 2010, Pages 19-23

  Huebinger, Ryan M ^a   Gomez, Ruben ^b   McGee, Daphne ^c   Chang, Ling Yu ^a   Bender, Jessica E ^d   O'Keeffe, Terence ^d   Burris, Agnes M ^a   Friese, Susan M ^d   Purdue, Gary F ^a   Hunt, John L ^a   Arnoldo, Brett D ^a   Horton, Jureta W ^a   Barber, Robert C ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b DETROIT MEDICAL CENTER   (United States)

^c BAYLOR UNIVERSITY   (United States)

^d UNIVERSITY OF ARIZONA   (United States)

Author keywords

Complex; Genetic association; Mitochondrial DNA polymorphism; Mitochondrial electron transport chain

Indexed keywords

GENOMIC DNA;

ADULT; ALLELE; ARTICLE; BURN; CAUCASIAN; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; HEART FAILURE; HUMAN; INCIDENCE; INJURY SCALE; KIDNEY FAILURE; LIVER FAILURE; MAJOR CLINICAL STUDY; MALE; MITOCHONDRION; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OUTCOMES RESEARCH; POLYMERASE CHAIN REACTION; RESPIRATORY CHAIN; RESPIRATORY FAILURE; RISK; SEPSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; BURNS; DNA, MITOCHONDRIAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; NADH DEHYDROGENASE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEPSIS; YOUNG ADULT;

EID: 73849110253     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181a99508     Document Type: Article

References (31)

1. Miller SF, Bessey PQ, Schurr MJ, Browning SM, Jeng JC, Caruso DM, Gomez M, Latenser BA, Lentz CW, Saffle JR, et al.: National Burn Repository 2005: a ten-year review. J Burn Care Res 27:411-436, 2006.
2. Karter M: Fire Loss in the United States During 2007. Quincy, MA: National Fire Protection Association, 2008.
3. Runyan CW, Casteel C, Perkis D, Black C, Marshall SW, Johnson RM, Coyne-Beasley T, Waller AE, Viswanathan S: Unintentional injuries in the home in the United States. Part I. Mortality. Am J Prev Med 28:73-79, 2005. (Pubitemid 40051330)
4. Merrell SW, Saffle JR, Larson CM, Sullivan JJ: The declining incidence of fatal sepsis following thermal injury. J Trauma 29:1362-1366, 1989.
5. Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis. N Engl J Med 348:138-150, 2003.
6. Angus DC, Wax RS: Epidemiology of sepsis: an update. Crit Care Med 29:S109-S116, 2001.
7. Friedman G, Silva E, Vincent JL: Has the mortality of septic shock changed with time. Crit Care Med 26:2078-2086, 1998.
8. Bloemsma GC, Dokter J, Boxma H, Oen IM: Mortality and causes of death in a burn centre. Burns 34:1103-1107, 2008.
9. Barber RC, Aragaki CC, Rivera-Chavez FA, Purdue GF, Hunt JL, Horton JW: TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury. J Med Genet 41:808-813, 2004.
10. McDaniel DO, Hamilton J, Brock M, May W, Calcote L, Tee LY, Vick L, Newman DB, Vick K, Harrison S, et al.: Molecular analysis of inflammatory markers in trauma patients at risk of postinjury complications. J Trauma 63:147-157; discussion 157-158, 2007.
11. Arcaroli J, Fessler MB, Abraham E: Genetic polymorphisms and sepsis. Shock 24:300-312, 2005.
12. O'Keefe GE, Hybki DL, Munford RS: The GY9A single nucleotide polymorphism at the j308 position in the tumor necrosis factor-alpha promoter increases the risk for severe sepsis after trauma. J Trauma 52:817-826, 2002.
13. Kudsk KA: Clinical applications of enteral nutrition. Nutr Clin Pract 9:165-171, 1994.
14. Militsa B: Nutrition in neurologic and neurosurgical critical care. Neurol India 49(suppl 1):S75-S79, 2001.
15. Sigalet DL, Mackenzie SL, Hameed SM: Enteral nutrition and mucosal immunity: implications for feeding strategies in surgery and trauma. Can J Surg 47:109-116, 2004.
16. Ross OA, McCormack R, Maxwell LD, Duguid RA, Quinn DJ, Barnett YA, Rea IM, El-Agnaf OM, Gibson JM, Wallace A, et al.: Mt4216c variant in linkage with the mtDNA TJ cluster may confer a susceptibility to mitochondrial dysfunction resulting in an increased risk of Parkinson's disease in the Irish. Exp Gerontol 38:397-405, 2003.
17. Rangelfrausto MS, Pittet D, Costigan M, Hwang T, Davis CS, Wenzel RP: The natural-history of the systemic inflammatory response syndrome (SIRS)Va prospective-study. J Am Med Assoc 273:117-123, 1995.
18. Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ: Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 23:1638-1652, 1995.
19. Huerta C, Castro MG, Coto E, Blazquez M, Ribacoba R, Guisasola LM, Salvador C, Martinez C, Lahoz CH, Alvarez V: Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population. J Neurol Sci 236:49-54, 2005.
20. Gomez R, O'Keeffe T, Chang LY, Huebinger RM, Minei JP, Barber RC: Association of mitochondrial variant allele 4216C with increased risk for complicated sepsis and death after traumatic injury. J Trauma 66:850Y857, 2009.
21. DiMauro S, Schon EA: Mitochondrial respiratory-chain diseases. N Engl J Med 348:2656-2668, 2003.
22. Swerdlow RH, Parks JK, Miller SW, Tuttle JB, Trimmer PA, Sheehan JP, Bennett JP Jr, Davis RE, Parker WD Jr: Origin and functional consequences of the complex I defect in Parkinson's disease. Ann Neurol 40:663-671, 1996.
23. Brealey D, Brand M, Hargreaves I, Heales S, Land J, Smolenski R, Davies NA, Cooper CE, Singer M: Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 360:219-223, 2002.
24. Svistunenko DA, Davies N, Brealey D, Singer M, Cooper CE: Mitochondrial dysfunction in patients with severe sepsis: an interrogation of individual respiratory chain components. Biochim Biophys Acta 1757:262-272, 2006.
25. Canter JA, Norris PR, Moore JH, Jenkins JM, Morris JA: Specific polymorphic variation in the mitochondrial genome and increased in-hospital mortality after severe trauma. Ann Surg 246:406-411, 2007.
26. Velez DR, Menon R, Simhan H, Fortunato S, Canter JA, Williams SM: Mitochondrial DNA variant a4917g, smoking and spontaneous preterm birth. Mitochondrion 8:130Y135, 2008.
27. Ruiz-Pesini E, Lapena AC, Diez-Sanchez C, Perez-Martos A, Montoya J, Alvarez E, Diaz M, Urries A, Montoro L, Lopez-Perez MJ, et al.: Human mtDNA haplogroups associated with high or reduced spermatozoa motility. Am J Hum Genet 67:682-696, 2000.
28. Hofmann S, Bezold R, Jaksch M, Kaufhold P, Obermaier-Kusser B, Gerbitz KD: Disease relevance of the so-called secondary leber hereditary optic neuropathy mutations. Am J Hum Genet 60:1539-1542, 1997.
29. Barber RC, Diaz-Arrastia R, Purdue GF: Searching for alleles associated with complicated outcomes after burn injury. J Burn Care Res 28:205-211, 2007.
30. Ioannidis JP, Bernstein J, Boffetta P, Danesh J, Dolan S, Hartge P, Hunter D, Inskip P, Jarvelin MR, Little J, et al.: A network of investigator networks in human genome epidemiology. Am J Epidemiol 162:302-304, 2005.
31. Seminara D, Khoury MJ, O'Brien TR, Manolio T, Gwinn ML, Little J, Higgins JP, Bernstein JL, Boffetta P, Bondy M, et al.: The emergence of networks in human genome epidemiology: challenges and opportunities. Epidemiology 18:1-8, 2007.