Prediction of blood-brain barrier penetration by drugs

Neuromethods

Volumn 45, Issue , 2010, Pages 63-83

  Lanevskij, Kiril ^a   Japertas, Pranas ^a   Didziapetris, Remigijus ^a   Petrauskas, Alanas ^a  

^a Pharma Algorithms Inc   (Lithuania)

Author keywords

Blood brain barrier; Brain uptake index; Drug transport; In situ perfusion; Non linear regression; Passive diffusion; Permeability; QSAR

Indexed keywords

4,7 DIHYDRO 3 ISOBUTYL 6 METHYL 4 (3 NITROPHENYL)THIENO[2,3 B]PYRIDINE 5 CARBOXYLIC ACID METHYL ESTER; 7 (3 BENZENESULFONAMIDOBICYCLO[2.2.1]HEPT 2 YL) 5 HEPTENOIC ACID; AMPHOLYTE; ANION; CARMUSTINE; CARRIER PROTEIN; CATION; ELACRIDAR; FLAVONOID; LOMUSTINE; PENTAZOCINE; POLYELECTROLYTE; QUERCETIN; SPIROMUSTINE; VALSPODAR; XENOBIOTIC AGENT;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN PERFUSION; COMPUTER MODEL; COMPUTER PREDICTION; DRUG BINDING; DRUG BLOOD LEVEL; DRUG DIFFUSION; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; MEMBRANE PERMEABILITY; NONHUMAN; PASSIVE MOVEMENT; PERMEABILITY BARRIER; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; SYSTEMATIC REVIEW; THEORETICAL STUDY; THERMODYNAMICS;

EID: 73849088293     PISSN: 08932336     EISSN: 19406045     Source Type: Book Series    
DOI: 10.1007/978-1-60761-529-3_4     Document Type: Article

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