ABC transporters: HDL-regulated gatekeepers at the endothelial border

Current Opinion in Lipidology

Volumn 20, Issue 6, 2009, Pages 526-527

  Jaccard, Evrim ^a   Widmann, Christian ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; CHOLESTEROL; ELASTASE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; ROSIGLITAZONE;

APOPTOSIS; ATHEROSCLEROSIS; BLOOD VESSEL; CELL PROTECTION; DIABETES MELLITUS; DIABETIC PATIENT; ENDOPLASMIC RETICULUM STRESS; GLUCOSE BLOOD LEVEL; HEART MUSCLE CELL; HUMAN; INSULINOMA; LIPID DIET; MACROPHAGE; NONHUMAN; NOTE; OBESITY; OSTEOBLAST; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TUMOR CELL; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CELL MEMBRANE PERMEABILITY; ENDOTHELIUM, VASCULAR; HUMANS; LIPOPROTEINS, HDL;

EID: 73849087298     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOL.0b013e3283330248     Document Type: Note

References (17)

1. Drew BG, Duffy SJ, Formosa MF, et al. High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation 2009; 119:2103-2111.
2. Rader DJ. Molecular regulation of HDL metabolism and function: implications for novel therapies. J Clin Invest 2006; 116:3090-3100.
3. Negre-Salvayre A, Dousset N, Ferretti G, et al. Antioxidant and cytoprotective properties of high-density lipoproteins in vascular cells. Free Radic Biol Med 2006; 41:1031-1040.
4. Mineo C, Deguchi H, Griffin JH, et al. Endothelial and antithrombotic actions of HDL. Circ Res 2006; 98:1352-1364.
5. Ortiz-Munoz G, Houard X, Martin-Ventura JL, et al. HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic property. FASEB J 2009; 23:3129-3139.
6. Rohrer L, Hersberger M, von Eckardstein A. High density lipoproteins in the intersection of diabetes mellitus, inflammation and cardiovascular disease. Curr Opin Lipidol 2004; 15:269-278.
7. Brodeur MR, Brissette L, Falstrault L, et al. HDL3 reduces the association and modulates the metabolism of oxidized LDL by osteoblastic cells: a protection against cell death. J Cell Biochem 2008; 105:1374-1385.
8. Van LS, Spillmann F, Riad A, et al. Human apolipoprotein A-I gene transfer reduces the development of experimental diabetic cardiomyopathy. Circulation 2008; 117:1563-1573.
9. Petremand J, Bulat N, Butty AC, et al. Involvement of 4E-BP1 in the protection induced by HDLs on pancreatic beta cells. Mol Endocrinol 2009; 23 (in press). [Epub ahead of print]
10. Tang C, Oram JF. The cell cholesterol exporter ABCA1 as a protector from cardiovasculardisease and diabetes. BiochimBiophysActa 2009; 1791:563-572.
11. Curtiss LK, Valenta DT, Hime NJ, et al. What is so special about apolipoprotein AI in reverse cholesterol transport? Arterioscler Thromb Vasc Biol 2006; 26:12-19.
12. Rohrer L, Ohnsorg PM, Lehner M, et al. High-density lipoprotein transport through aortic endothelial cells involves scavenger receptor BI and ATP-binding cassette transporter G1. Circ Res 2009; 104:1142-1150.
13. CavelierC, Rohrer L, von EA. ATP-Binding cassette transporter A1 modulates apolipoprotein A-I transcytosis through aortic endothelial cells. Circ Res 2006; 99:1060-1066.
14. Terasaka N, Wang N, Yvan-Charvet L, et al. High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. Proc Natl Acad Sci USA 2007; 38:15093-15098.
15. Terasaka N, Yu S, Yvan-Charvet L, et al. ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. J Clin Invest 2008; 118:3701-3713.
16. Rutti S, Ehses JA, Sibler RA, et al. Low and high-density lipoproteins modulate function, apoptosis and proliferation of primary human and murine pancreatic beta cells. Endocrinology 2009; 150:4521-4530.
17. Kanda T, Brown JD, Orasanu G, et al. PPAR7 in the endothelium regulates metabolic responses to high-fat diet in mice. J Clin Invest 2009; 119:110-124.