Effect of nicotinamide on early graft failure following intraportal islet transplantation

Experimental and Molecular Medicine

Volumn 41, Issue 11, 2009, Pages 782-792

  Jung, Da Yeon ^a   Park, Jae Berm ^b   Joo, Sung Yeon ^a   Joh, Jae Won ^b   Kwon, Choon Hyuck ^b   Kwon, Ghee Young ^b   Kim, Sung Joo ^a,b  

^a Samsung Medical Center   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Diabetes mellitus, type 1; Hepatectomy; Islets of Langerhans; Islets of Langerhans transplantation; Niacinamide

Indexed keywords

GLUCOSE; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; NICOTINAMIDE; STREPTOZOCIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; FUNCTIONAL ASSESSMENT; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLYCEMIC CONTROL; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; ISOGRAFT; MALE; MOUSE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PARTIAL HEPATECTOMY; PROTEIN BLOOD LEVEL; RECURRENT DISEASE; STREPTOZOCIN DIABETES; TISSUE CULTURE;

MUS;

EID: 73649112091     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.11.084     Document Type: Article

References (31)

1. Andersen HU, Jorgensen KH, Egeberg J, Mandrup-Poulsen T, Nerup J. Nicotinamide prevents interleukin-1 effects on accumulated insulin release and nitric oxide production in rat islets of Langerhans. Diabetes 1994;43:770-7
2. Andrades P, Asiedu C, Rodriguez C, Goodwin J, Deckard LA, Jargal U, Balgansuren G, Thomas JM. Insulin secretion from pancreatic islets in fibrin glue clots at different fibrinogen and thrombin concentrations. Transplant Proc 2007;39:1607-8
3. Beattie GM, Montgomery AM, Lopez AD, Hao E, Perez B, Just ML, Lakey JR, ME Hart and A. Hayek. A novel approach to increase human islet cell mass while preserving β-cell function. Diabetes 2002;51:3435-9
4. Berman DM, Cabrera O, Kenyon NM, Miller J, Tam SH, Khandekar VS, Picha KM, Soderman AR, Jordan RE, Bugelski PJ, Horninger D, Lark M, Davis JE, Alejandro R, Berggren PO, Zimmerman M, O'Neil JJ, Ricordi C, Kenyon NS. Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model. Transplantation 2007;84:308-15
5. Buscema M, Vinci C, Gatta C, Rabuazzo MA, Vignen R, Purrello F. Nicotinamide partially reverses the interleukin-1 beta inhibition of glucose-induced insulin release in pancreatic islets. Metabolism 1992;41:296-300
6. Chase P, Dupre J, Mahon J, Ehrlich R, Gale E, Kolb H, Lampeter E, Nerup J. Nicotinamide and prevention of diabetes. Lancet 1992;339:1051-2
7. Contreras JL, Eckstein C, Smyth CA, Bilbao G, Vilatoba M, Ringland SE, Young C, Thompson JA, Fernandez JA, Griffin JH, Eckhoff DE. Activated protein C preserves functional islet mass after intraportal transplantation: a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death. Diabetes 2004; 53:2804-14
8. Eich T, Eriksson O, Sundin A, Estrada S, Brandhorst D, Brandhorst H, Langstrom B, Nilsson B, Korsgren O, Lundgren T. Positron emission tomography: a real-time tool to quantify early islet engraftment in a preclinical large animal model. Transplantation 2007;84:893-8
9. Elliott RB, Chase HP. Prevention or delay of type 1 (insulin-dependent) diabetes mellitus in children using nicotinamide. Diabetologia 1991;34:362-5
10. Goss JA, Schock AP, Brunicardi FC, Goodpastor SE, Garber AJ, Soltes G, Barth M, Froud T, Alejandro R, Ricordi C. Achievement of insulin independence in three consecutive type-1 diabetic patients via pancreatic islet transplantation using islets isolated at a remote islet isolation center. Transplantation 2002;74:1761-6
11. Goto M, Johansson H, Maeda A, Elgue G, Korsgren O, Nilsson B. Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets. Transplantation 2004;77:741-7
12. Gotoh M, Maki T, Satomi S, Porter J, Monaco AP. Immunological characteristics of purified pancreatic islet grafts. Transplantation 1986;42:387-90
13. Greene AK, Puder M. Partial hepatectomy in the mouse: technique and perioperative management. J Invest Surg 2003;16:99-102
14. Hara M, Yin D, Dizon RF, Shen J, Chong AS, Bindokas VP. A mouse model for studying intrahepatic islet transplantation. Transplantation 2004;78:615-8
15. Hellerstrom C. The life story of the pancreatic B cell. Diabetologia 1984;26:393-400
16. Ichii H, Wang X, Messinger S, Alvarez A, Fraker C, Khan A, Kuroda Y, Inverardi L, Goss JA, Alejandro R, Ricordi C. Improved human islet isolation using nicotinamide. Am J Transplant 2006;6:2060-8
17. Jung DY, Lee HJ, Lee EN, Lee J, Kim EY, Park HJ, Chang CY, Lee SK, Joh JW, Kwon GY, Kim SJ. Beneficial effects of simultaneous treatment with 15-deoxyspergualin and monoclonal antibodies to CD45RB and CD154 on murine islet transplantation recipients. Transplantation 2006;82:188-95
18. Jung DY, Kim EY, Joo SY, Park JB, Moon C, Kim SH, Sim EY, Joh JW, Kwon CH, Kwon GY, Kim SJ. Prolonged survival of islet allografts in mice treated with rosmarinic acid and anti-CD154 antibody. Exp Mol Med 2008;40:1-10
19. Kallmann B, Burkart V, Kroncke KD, Kolb-Bachofen V, Kolb H. Toxicity of chemically generated nitric oxide towards pancreatic islet cells can be prevented by nicotinamide. Life Sci 1992;51:671-8
20. Kolb H, Burkart V, Appels B, Hanenberg H, Kantwerk-Funke G, Kiesel U, Funda J, Schraermeyer U, Kolb-Bachofen V. Essential contribution of macrophages to islet cell destruction in vivo and in vitro. J Autoimmun 1990;3 Suppl 1:117-20
21. Korsgren O, Andersson A, Sandler S. Pretreatment of fetal porcine pancreas in culture with nicotinamide accelerates reversal of diabetes after transplantation to nude mice. Surgery 1993;113:205-14
22. Markmann JF, Deng S, Huang X, Desai NM, Velidedeoglu EH, Lui C, Frank A, Markmann E, Palanjian M, Brayman K, Wolf B, Bell E, Vitamaniuk M, Doliba N, Matschinsky F, Barker CF, Naji A. Insulin independence following isolated islet transplantation and single islet infusions. Ann Surg 2003;237:741-9; discussion 749-50
23. Moberg L. The role of the innate immunity in islet transplantation. Ups J Med Sci 2005;110:17-55
24. Moberg L, Johansson H, Lukinius A, Berne C, Foss A, Kallen R, Ostraat O, Salmela K, Tibell A, Tufveson G, Elgue G, Nilsson Ekdahl K, Korsgren O, Nilsson B. Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet 2002;360:2039-45
25. Moberg L, Olsson A, Berne C, Felldin M, Foss A, Kallen R, Salmela K, Tibell A, Tufveson G, Nilsson B, Korsgren O. Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation. Transplantation 2003;76:1285-8
26. Morales AP, Conde EG, Lopez MG, Valle MI, Diaz JF, Jauregui PH. An improved method of 90% pancreatectomy using a low dose of streptozotocin at the pancreaticoduodenal artery results in a rapid diabetic stage in dogs. Acta Diabetol 2005;42:153-5
27. Ozmen L, Ekdahl KN, Elgue G, Larsson R, Korsgren O, Nilsson B. Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 2002;51:1779-84
28. Piemonti L, Leone BE, Nano R, Saccani A, Monti P, Maffi P, Bianchi G, Sica A, Peri G, Melzi R, Aldrighetti L, Secchi A, Di Carlo V, Allavena P, Bertuzzi F. 2002. "Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation." Diabetes 2002;51:55-65
29. Pipeleers D, Van de Winkel M. Pancreatic B cells possess defense mechanisms against cell-specific toxicity. Proc Natl Acad Sci USA 1986;83:5267-71
30. Sandler S, Andersson A. Stimulation of cell replication in transplanted pancreatic islets by nicotinamide treatment. Transplantation 1988;46:30-1
31. Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth E, Warnock GL, Kneteman NM, Rajotte RV. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-8