Positron emission tomography: A real-time tool to quantify early islet engraftment in a preclinical large animal model

Transplantation

Volumn 84, Issue 7, 2007, Pages 893-898

  Eich, Torsten ^a   Eriksson, Olof ^a,b   Sundin, Anders ^a   Estrada, Sergio ^b   Brandhorst, Daniel ^a   Brandhorst, Heide ^a   Langstrom, Bengt ^b,c   Nilsson, Bo ^a   Korsgren, Olle ^a   Lundgren, Torbjorn ^d,e  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b BIACORE AB   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

^d KAROLINSKA INSTITUTE   (Sweden)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Imaging; Islets; PET scanning; Transplantation

Indexed keywords

FLUORODEOXYGLUCOSE F 18; GLUCOSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SURVIVAL; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG RELEASE; ENGRAFTMENT; IN VITRO STUDY; NONHUMAN; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RADIOACTIVITY; SWINE; URINARY EXCRETION; ANIMAL; AUTORADIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CYTOLOGY; DIAGNOSTIC IMAGING; DISEASE MODEL; GRAFT SURVIVAL; METABOLISM; METHODOLOGY; PANCREAS ISLET; POSITRON EMISSION TOMOGRAPHY; TIME;

ANIMALS; AUTORADIOGRAPHY; DIAGNOSTIC IMAGING; DISEASE MODELS, ANIMAL; GLUCOSE; GRAFT SURVIVAL; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; POSITRON-EMISSION TOMOGRAPHY; SWINE; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED;

EID: 38449096226     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000284730.86567.9f     Document Type: Article

References (14)

1. Shapiro AM, Lakey JR, Ryan EA, Korbutt GS, Toth, E, Warnock GL, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000; 343: 230.
2. Shapiro AM, Ricordi C, Hering BJ, Auchincloss H, Lindblad R, Robertson RP, et al. International trial of the Edmonton protocol for islet transplantation. N Engl J Med 2006; 355: 1318.
3. Bennet W, Sundberg B, Groth CG, Brendel MD, Brandhorst D, Brandhorst H, et al. Incompatibility between human blood and isolated islets of Langerhans: A finding with implications for clinical intraportal islet transplantation? Diabetes 1999; 48: 1907.
4. Moberg L, Johansson H, Lukinius A, Berne C, Foss A, Kallen R, et al. Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation. Lancet 2002; 360: 2039.
5. Johansson H, Lukinius A, Moberg L, Lundgren T, Berne C, Foss A, et al. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation. Diabetes 2005; 54: 1755.
6. Berman D, Cabrera O, Kenyon NM, Tam S, Khandekar V, Picha, K, et al. Effect of inhibition of tissue factor on nonhuman primate islet allograft survival Abstract: World transplantation congress July 22-27, 2006, Boston, Massachusetts. Am J Transplant 2006; 6 Suppl 2: 156.
7. Sokoloff L, Reivich M, Kennedy C, Des Rosiers MH, Patlak CS, Pettigrew KD, et al. The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 1977; 28: 897.
8. Gallagher B, Fowler J, Gutterson N, MacGregor R, Wan C-N, Wolf A. Metabolic Trapping as a Principle of Radiopharmaceutical design: Some factors responsible for the biodistribution of [18F]2-Deoxy-2-Fluoro-D-Glucose. J Nucl Med 1978; 19: 1154.
9. Tamura M, Unno K, Yonezawa S, Hattori K, Nakashima E, Tsukada H, et al. In vivo trafficking of endothelial progenitor cells their possible involvement in the tumor neovascularization. Life Sci 2004; 75: 575.
10. Brandhorst H, Brandhorst D, Hering BJ, Bretzel RG. Significant progress in porcine islet mass isolation utilizing liberase HI for enzymatic low-temperature pancreas digestion. Transplantation 1999; 68: 355.
11. Berney T, Mamin A, Shapiro AM, Ritz-Laser B, Brulhart MC, Toso C, et al. Detection of insulin mRNA in the peripheral blood after human islet transplantion predicts deterioration of metabolic control. Am J Transplant 2006; 6: 1704.
12. Lu Y, Dang H, Middleton B, Zhang Z, Washburn L, Stout DB, et al. Noninvasive imaging of islet grafts using positron-emission tomography. Proc Natl Acad Sci U S A 2006; 103: 11294.
13. Toso C, Dang H, Middleton B, Zhang Z, Washburn L, Stout DB, et al. Positron-emission tomography imaging of early events after transplantation of islets of Langerhans. Transplantation 2005; 79: 353.
14. Hirshberg B, Montgomery S, Wysoki MG, Xu H, Tadaki D, Lee J, et al. Pancreatic islet transplantation using the nonhuman primate (rhesus) model predicts that the portal vein is superior to the celiac artery as the islet infusion site. Diabetes 2002; 51(7): 2135.