-
1
-
-
34247109045
-
Natural products as sources of new drugs over the last 25 years
-
Newman, D. J. & Cragg, G. M. Natural products as sources of new drugs over the last 25 years. J. Nat. Prod. 70, 461-477 (2007).
-
(2007)
J. Nat. Prod.
, vol.70
, pp. 461-477
-
-
Newman, D.J.1
Cragg, G.M.2
-
2
-
-
0037046560
-
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)
-
Bentley, S. D. et al. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417, 141-147 (2002).
-
(2002)
Nature
, vol.417
, pp. 141-147
-
-
Bentley, S.D.1
-
3
-
-
0038561132
-
Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis
-
Ikeda,H.et al. Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis. Nat. Biotechnol. 21, 526-531 (2003).
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 526-531
-
-
Ikeda, H.1
-
4
-
-
44349169524
-
Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350
-
Ohnishi, Y. et al. Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350. J. Bacteriol. 190, 4050-4060 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, pp. 4050-4060
-
-
Ohnishi, Y.1
-
5
-
-
34248349446
-
Mutations in rsmG encoding a 16S rRNA methyltransferase result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2)
-
Nishimura, K., Hosaka, T., Tokuyama, S., Okamoto, S. & Ochi, K. Mutations in rsmG, encoding a 16S rRNA methyltransferase, result in low-level streptomycin resistance and antibiotic overproduction in Streptomyces coelicolor A3(2). J. Bacteriol. 189, 3876-3883 (2007).
-
(2007)
J. Bacteriol.
, vol.189
, pp. 3876-3883
-
-
Nishimura, K.1
Hosaka, T.2
Tokuyama, S.3
Okamoto, S.4
Ochi, K.5
-
6
-
-
67650469476
-
Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetes
-
Tanaka, Y. et al. Antibiotic overproduction by rpsL and rsmG mutants of various actinomycetes. Appl. Environ. Microbiol. 75, 4919-4922 (2009).
-
(2009)
Appl. Environ. Microbiol.
, vol.75
, pp. 4919-4922
-
-
Tanaka, Y.1
-
7
-
-
43049129603
-
Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutations
-
Wang, G., Hosaka, T. & Ochi, K. Dramatic activation of antibiotic production in Streptomyces coelicolor by cumulative drug resistance mutations. Appl. Environ. Microbiol. 74, 2834-2840 (2008).
-
(2008)
Appl. Environ. Microbiol.
, vol.74
, pp. 2834-2840
-
-
Wang, G.1
Hosaka, T.2
Ochi, K.3
-
8
-
-
34347344063
-
From microbial differentiation to ribosome engineering
-
Ochi, K. From microbial differentiation to ribosome engineering. Biosci. Biotechnol. Biochem. 71, 1373-1386 (2007).
-
(2007)
Biosci. Biotechnol. Biochem.
, vol.71
, pp. 1373-1386
-
-
Ochi, K.1
-
9
-
-
0242405881
-
Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus
-
Tamehiro, N. et al. Innovative approach for improvement of an antibiotic-overproducing industrial strain of Streptomyces albus. Appl. Environ. Microbiol. 69, 6412-6417 (2003).
-
(2003)
Appl. Environ. Microbiol.
, vol.69
, pp. 6412-6417
-
-
Tamehiro, N.1
-
10
-
-
33644765065
-
Antibiotic production improvement in the rare actinomycete Planobispora rosea by selection of mutants resistant to the aminoglycosides streptomycin and gentamycin and to rifamycin
-
Beltrametti, F., Rossi, R., Selva, E. & Marinelli, F. Antibiotic production improvement in the rare actinomycete Planobispora rosea by selection of mutants resistant to the aminoglycosides streptomycin and gentamycin and to rifamycin. J. Ind. Microbiol. Biotechnol. 33, 283-288 (2006).
-
(2006)
J. Ind. Microbiol. Biotechnol.
, vol.33
, pp. 283-288
-
-
Beltrametti, F.1
Rossi, R.2
Selva, E.3
Marinelli, F.4
-
11
-
-
0023626550
-
Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: Significance of the stringent response (ppGpp) and GTP content in relation to A factor
-
Ochi, K. Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor. J. Bacteriol. 169, 3608-3616 (1987).
-
(1987)
J. Bacteriol.
, vol.169
, pp. 3608-3616
-
-
Ochi, K.1
-
12
-
-
0037226133
-
Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2)
-
Okamoto, S., Lezhava, A., Hosaka, T., Okamoto Hosoya, Y. & Ochi, K. Enhanced expression of S-adenosylmethionine synthetase causes overproduction of actinorhodin in Streptomyces coelicolor A3(2). J. Bacteriol. 185, 601-609 (2003).
-
(2003)
J. Bacteriol.
, vol.185
, pp. 601-609
-
-
Okamoto, S.1
Lezhava, A.2
Hosaka, T.3
Okamoto Hosoya, Y.4
Ochi, K.5
-
13
-
-
4444374760
-
Effect of S-adenosylmethionine on antibiotic production in Streptomyces griseus and Streptomyces griseoflavus
-
Saito, N., Kurosawa, K., Xu, J., Okamoto, S. & Ochi, K. Effect of S-adenosylmethionine on antibiotic production in Streptomyces griseus and Streptomyces griseoflavus. Actinomycetologica 17, 47-49 (2003).
-
(2003)
Actinomycetologica
, vol.17
, pp. 47-49
-
-
Saito, N.1
Kurosawa, K.2
Xu, J.3
Okamoto, S.4
Ochi, K.5
-
14
-
-
33646723495
-
S-adenosylmethionine activates adpA transcription and promotes streptomycin biosynthesis in Streptomyces griseus
-
Shin, S. K., Xu, D., Kwon, H. J. & Suh, J. W. S-adenosylmethionine activates adpA transcription and promotes streptomycin biosynthesis in Streptomyces griseus. FEMS Microbiol. Lett. 259, 53-59 (2006).
-
(2006)
FEMS Microbiol. Lett.
, vol.259
, pp. 53-59
-
-
Shin, S.K.1
Xu, D.2
Kwon, H.J.3
Suh, J.W.4
-
15
-
-
0028874933
-
The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites
-
Retzlaff, L. & Distler, J. The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites. Mol. Microbiol. 18, 151-162 (1995).
-
(1995)
Mol. Microbiol.
, vol.18
, pp. 151-162
-
-
Retzlaff, L.1
Distler, J.2
-
16
-
-
17844392892
-
A central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus
-
Ohnishi, Y., Yamazaki, H., Kato, J. Y., Tomono, A. & Horinouchi, S. AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus. Biosci. Biotechnol. Biochem. 69, 431-439 (2005).
-
(2005)
Biosci. Biotechnol. Biochem.
, vol.69
, pp. 431-439
-
-
Ohnishi, Y.1
Yamazaki, H.2
Kato, J.Y.3
Tomono, A.4
Adpa, H.S.5
-
17
-
-
66149185679
-
Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12
-
Hosaka, T. et al. Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12. Nat. Biotechnol. 27, 462-464 (2009).
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 462-464
-
-
Hosaka, T.1
-
18
-
-
46449120734
-
Feast or famine: The global regulator DasR links nutrient stress to antibiotic production by Streptomyces
-
Rigali, S. et al. Feast or famine: the global regulator DasR links nutrient stress to antibiotic production by Streptomyces. EMBO Rep. 9, 670-675 (2008).
-
(2008)
EMBO Rep
, vol.9
, pp. 670-675
-
-
Rigali, S.1
-
19
-
-
64949203863
-
Phenotypes and gene expression profiles of Saccharopolyspora erythraea rifampicin-resistant (rif) mutants affected in erythromycin production
-
Carata, E. et al. Phenotypes and gene expression profiles of Saccharopolyspora erythraea rifampicin-resistant (rif) mutants affected in erythromycin production. Microb. Cell. Fact. 8, 18 (2009).
-
(2009)
Microb. Cell. Fact.
, vol.8
, pp. 18
-
-
Carata, E.1
-
20
-
-
63449126395
-
Activation of dormant bacterial genes by Nonomuraea sp. strain ATCC 39727 mutant-type RNA polymerase
-
Tala, A. et al. Activation of dormant bacterial genes by Nonomuraea sp. strain ATCC 39727 mutant-type RNA polymerase. J. Bacteriol. 191, 805-814 (2009).
-
(2009)
J. Bacteriol.
, vol.191
, pp. 805-814
-
-
Tala, A.1
|