Spontaneous and 5-fluorouracil-induced centrosome amplification lowers the threshold to resveratrol-evoked apoptosis in colon cancer cells

Cancer Letters

Volumn 288, Issue 1, 2010, Pages 36-41

  Lee, Shao Chin ^a   Chan, Jason Yongsheng ^a   Pervaiz, Shazib ^a,b,c,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d SINGAPORE MIT ALLIANCE   (Singapore)

Author keywords

5 Fluorouracil; Apoptosis sensitivity; Caspase 6; Centrosome amplification; Chemosensitization; p53; Resveratrol

Indexed keywords

CASPASE 6; FLUOROURACIL; PROTEIN P53; RESVERATROL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CENTROSOME; CHEMOSENSITIZATION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CASPASE 6; CENTROSOME; COLONIC NEOPLASMS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; FLUOROURACIL; HCT116 CELLS; HUMANS; STILBENES; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 73649086264     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.06.020     Document Type: Article

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