메뉴 건너뛰기




Volumn 24, Issue 1, 2010, Pages 204-217

In vivo targeting of the growth hormone receptor (GHR) Box1 sequence demonstrates that the GHR does not signal exclusively through JAK2

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; GROWTH HORMONE RECEPTOR; JANUS KINASE 2; LIVER ENZYME; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SOMATOMEDIN BINDING PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN; STEROID RECEPTOR COACTIVATOR 1;

EID: 73549121928     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2009-0233     Document Type: Article
Times cited : (66)

References (43)
  • 2
    • 0028097219 scopus 로고
    • Interaction of the GH receptor cytoplasmic domain with the JAK2 tyrosine kinase
    • Frank SJ, Gilliland G, Kraft AS, Arnold CS 1994 Interaction of the GH receptor cytoplasmic domain with the JAK2 tyrosine kinase. Endocrinology 135:2228-2239
    • (1994) Endocrinology , vol.135 , pp. 2228-2239
    • Frank, S.J.1    Gilliland, G.2    Kraft, A.S.3    Arnold, C.S.4
  • 6
    • 0037160137 scopus 로고    scopus 로고
    • Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent
    • Zhu T, Ling L, Lobie PE 2002 Identification of a JAK2-independent pathway regulating growth hormone (GH)-stimulated p44/42 mitogen-activated protein kinase activity. GH activation of Ral and phospholipase D is Src-dependent. J Biol Chem 277:45592-45603
    • (2002) J Biol Chem , vol.277 , pp. 45592-45603
    • Zhu, T.1    Ling, L.2    Lobie, P.E.3
  • 9
    • 0035980057 scopus 로고    scopus 로고
    • CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling
    • Arai A, Kanda E, Nosaka Y, Miyasaka N, Miura O 2001 CrkL is recruited through its SH2 domain to the erythropoietin receptor and plays a role in Lyn-mediated receptor signaling. J Biol Chem 276:33282-33290
    • (2001) J Biol Chem , vol.276 , pp. 33282-33290
    • Arai, A.1    Kanda, E.2    Nosaka, Y.3    Miyasaka, N.4    Miura, O.5
  • 10
    • 27844510453 scopus 로고    scopus 로고
    • Heterozygote effects in mice with partial truncations in the growth hormone receptor cytoplasmic domain: Assessment of growth parameters and phenotype
    • Rowland JE, Kerr LM, White M, Noakes PG, Waters MJ 2005 Heterozygote effects in mice with partial truncations in the growth hormone receptor cytoplasmic domain: assessment of growth parameters and phenotype. Endocrinology 146:5278-5286
    • (2005) Endocrinology , vol.146 , pp. 5278-5286
    • Rowland, J.E.1    Kerr, L.M.2    White, M.3    Noakes, P.G.4    Waters, M.J.5
  • 13
    • 0034457934 scopus 로고    scopus 로고
    • Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: Developmental regulation and role in male-specific liver gene expression
    • Choi HK, Waxman DJ 2000 Plasma growth hormone pulse activation of hepatic JAK-STAT5 signaling: developmental regulation and role in male-specific liver gene expression. Endocrinology 141:3245-3255
    • (2000) Endocrinology , vol.141 , pp. 3245-3255
    • Choi, H.K.1    Waxman, D.J.2
  • 14
    • 0031953831 scopus 로고    scopus 로고
    • STAT3 activation by Src induces specific gene regulation and is required for cell transformation
    • Turkson J, Bowman T, Garcia R, Caldenhoven E, De Groot RP, Jove R 1998 STAT3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol 18:2545-2552
    • (1998) Mol Cell Biol , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 15
    • 0033696214 scopus 로고    scopus 로고
    • Identification of genes induced by GH in rat liver using cDNA arrays
    • Thompson BJ, Shang CA, Waters MJ 2000 Identification of genes induced by GH in rat liver using cDNA arrays. Endocrinology 141: 4321-4324
    • (2000) Endocrinology , vol.141 , pp. 4321-4324
    • Thompson, B.J.1    Shang, C.A.2    Waters, M.J.3
  • 16
    • 33744497029 scopus 로고    scopus 로고
    • Sex-dependent liver gene expression is extensive and largely dependent on STAT5b: STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis
    • Clodfelter KH, Holloway MG, Hodor P, Park SH, Ray WJ, Waxman DJ 2006 Sex-dependent liver gene expression is extensive and largely dependent on STAT5b: STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis. Mol Endocrinol 20:1333-1351
    • (2006) Mol Endocrinol , vol.20 , pp. 1333-1351
    • Clodfelter, K.H.1    Holloway, M.G.2    Hodor, P.3    Park, S.H.4    Ray, W.J.5    Waxman, D.J.6
  • 18
    • 34249795488 scopus 로고    scopus 로고
    • Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus
    • Holloway MG, Cui Y, Laz EV, Hosui A, Hennighausen L, Waxman DJ 2007 Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus. Endocrinology 148:1977-1986
    • (2007) Endocrinology , vol.148 , pp. 1977-1986
    • Holloway, M.G.1    Cui, Y.2    Laz, E.V.3    Hosui, A.4    Hennighausen, L.5    Waxman, D.J.6
  • 19
    • 38749154654 scopus 로고    scopus 로고
    • Expression of the hepatic specific V1 messenger ribonucleic acid of the human growth hormone receptor gene is regulated by hepatic nuclear factor (HNF)-4α2 and HNF-4α8
    • Goodyer CG, Rhani Z, Zheng H 2008 Expression of the hepatic specific V1 messenger ribonucleic acid of the human growth hormone receptor gene is regulated by hepatic nuclear factor (HNF)-4α2 and HNF-4α8. Mol Endocrinol 2008 22:485-500
    • (2008) Mol Endocrinol 2008 , vol.22 , pp. 485-500
    • Goodyer, C.G.1    Rhani, Z.2    Zheng, H.3
  • 20
    • 3042737045 scopus 로고    scopus 로고
    • Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and hepatocyte nuclear factor 4γ(HNF-4γ) and HNF-4αregulate the bovine growth hormone receptor 1A promoter through a common DNA element
    • Xu Q, Walther N, Jiang H 2004 Chicken ovalbumin upstream promoter transcription factor II (COUP-TFII) and hepatocyte nuclear factor 4γ(HNF-4γ) and HNF-4αregulate the bovine growth hormone receptor 1A promoter through a common DNA element. J Mol Endocrinol 32:947-961
    • (2004) J Mol Endocrinol , vol.32 , pp. 947-961
    • Xu, Q.1    Walther, N.2    Jiang, H.3
  • 21
    • 30944447568 scopus 로고    scopus 로고
    • The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
    • Yoon S, Seger R 2006 The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions. Growth Factors 24:21-44
    • (2006) Growth Factors , vol.24 , pp. 21-44
    • Yoon, S.1    Seger, R.2
  • 22
    • 38549117402 scopus 로고    scopus 로고
    • SLIP1, a factor required for activation of histonemRNAtranslation by the stem-loop binding protein
    • Cakmakci NG, Lerner RS, Wagner EJ, Zheng L, Marzluff WF 2008 SLIP1, a factor required for activation of histonemRNAtranslation by the stem-loop binding protein. Mol Cell Biol 28:1182-1194
    • (2008) Mol Cell Biol , vol.28 , pp. 1182-1194
    • Cakmakci, N.G.1    Lerner, R.S.2    Wagner, E.J.3    Zheng, L.4    Marzluff, W.F.5
  • 23
    • 4043059447 scopus 로고    scopus 로고
    • Pituitary tumor transforming gene: An update
    • Yu R, Melmed S 2004 Pituitary tumor transforming gene: an update. Front Horm Res 32:175-185
    • (2004) Front Horm Res , vol.32 , pp. 175-185
    • Yu, R.1    Melmed, S.2
  • 26
    • 33645649507 scopus 로고    scopus 로고
    • Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription
    • Chia DJ, Ono M, Woelfle J, Schlesinger-Massart M, Jiang H, Rotwein P 2006 Characterization of distinct Stat5b binding sites that mediate growth hormone-stimulated IGF-I gene transcription. J Biol Chem 281:3190-3197
    • (2006) J Biol Chem , vol.281 , pp. 3190-3197
    • Chia, D.J.1    Ono, M.2    Woelfle, J.3    Schlesinger-Massart, M.4    Jiang, H.5    Rotwein, P.6
  • 27
    • 0035175162 scopus 로고    scopus 로고
    • Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth
    • Lupu F, Terwilliger JD, Lee K, Segre GV, Efstratiadis A 2001 Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol 229:141-162
    • (2001) Dev Biol , vol.229 , pp. 141-162
    • Lupu, F.1    Terwilliger, J.D.2    Lee, K.3    Segre, G.V.4    Efstratiadis, A.5
  • 28
    • 21344434092 scopus 로고    scopus 로고
    • The regulation of fatty acid synthase by STAT5A
    • Hogan JC, Stephens JM 2005 The regulation of fatty acid synthase by STAT5A. Diabetes 54:1968-1975
    • (2005) Diabetes , vol.54 , pp. 1968-1975
    • Hogan, J.C.1    Stephens, J.M.2
  • 29
    • 34249742693 scopus 로고    scopus 로고
    • The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression by prolactin or growth hormone in adipocytes
    • White UA, Coulter AA, Miles TK, Stephens JM 2007 The STAT5A-mediated induction of pyruvate dehydrogenase kinase 4 expression by prolactin or growth hormone in adipocytes. Diabetes 56:1623-1629
    • (2007) Diabetes , vol.56 , pp. 1623-1629
    • White, U.A.1    Coulter, A.A.2    Miles, T.K.3    Stephens, J.M.4
  • 30
    • 0033575871 scopus 로고    scopus 로고
    • Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice
    • Fain JN, Ihle JN, Bahouth SW 1999 Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice. Biochem Biophys Res Commun 263:201-205
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 201-205
    • Fain, J.N.1    Ihle, J.N.2    Bahouth, S.W.3
  • 32
    • 48249130514 scopus 로고    scopus 로고
    • JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells
    • Jin H, Lanning NJ, Carter-Su C 2008 JAK2, but not Src family kinases, is required for STAT, ERK, and Akt signaling in response to growth hormone in preadipocytes and hepatoma cells. Mol Endocrinol 22:1825-1841
    • (2008) Mol Endocrinol , vol.22 , pp. 1825-1841
    • Jin, H.1    Lanning, N.J.2    Carter-Su, C.3
  • 33
    • 33751536492 scopus 로고    scopus 로고
    • Phospholipase Cγ1 negatively regulates GH signaling by forming a ternary complex with JAK2 and protein tyrosine phosphatase-1B
    • Choi JH, Kim HS, Kim SH, Yang YR, Bae YS, Chang JS, Kwon HM, Ryu SH, Suh PG 2006 Phospholipase Cγ1 negatively regulates GH signaling by forming a ternary complex with JAK2 and protein tyrosine phosphatase-1B. Nat Cell Biol 8:1389-1397
    • (2006) Nat Cell Biol , vol.8 , pp. 1389-1397
    • Choi, J.H.1    Kim, H.S.2    Kim, S.H.3    Yang, Y.R.4    Bae, Y.S.5    Chang, J.S.6    Kwon, H.M.7    Ryu, S.H.8    Suh, P.G.9
  • 34
    • 49049110327 scopus 로고    scopus 로고
    • Genomic dissection of the cytokine-controlled STAT5 signaling network in liver
    • Hosui A, Hennighausen L 2008 Genomic dissection of the cytokine-controlled STAT5 signaling network in liver. Physiol Genomics 34:135-143
    • (2008) Physiol Genomics , vol.34 , pp. 135-143
    • Hosui, A.1    Hennighausen, L.2
  • 35
    • 37349020115 scopus 로고    scopus 로고
    • How GH controls growth, obesity and sexual dimorphism
    • Lichanska AM, Waters MJ 2008 How GH controls growth, obesity and sexual dimorphism. Trends Genet 24:41-47
    • (2008) Trends Genet , vol.24 , pp. 41-47
    • Lichanska, A.M.1    Waters, M.J.2
  • 36
    • 25444486937 scopus 로고    scopus 로고
    • Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1
    • Vigneron A, Roninson IB, Gamelin E, Coqueret O 2005 Src inhibits adriamycin-induced senescence and G2 checkpoint arrest by blocking the induction of p21waf1. Cancer Res 65:8927-8935
    • (2005) Cancer Res , vol.65 , pp. 8927-8935
    • Vigneron, A.1    Roninson, I.B.2    Gamelin, E.3    Coqueret, O.4
  • 37
    • 0141592530 scopus 로고    scopus 로고
    • Cloning and characterization of the human UDP- glucuronosyltransferase 1A8, 1A9 and 1A10 gene promoters: Differential regulation through an interior-like region
    • Gregory PA, Gardner-Stephen DA, Lewinsky RH, Duncliffe KN, Mackenzie PI 2003 Cloning and characterization of the human UDP- glucuronosyltransferase 1A8, 1A9 and 1A10 gene promoters: differential regulation through an interior-like region. J Biol Chem 278:3601-3614
    • (2003) J Biol Chem , vol.278 , pp. 3601-3614
    • Gregory, P.A.1    Gardner-Stephen, D.A.2    Lewinsky, R.H.3    Duncliffe, K.N.4    Mackenzie, P.I.5
  • 38
    • 0030990092 scopus 로고    scopus 로고
    • Cloning and characterization of the rat apobec-1 gene: A comparative analysis of gene structure and promoter usage in the mouse and rat
    • Hirano K, Min J, Funahashi T, Davidson NO 1997 Cloning and characterization of the rat apobec-1 gene: a comparative analysis of gene structure and promoter usage in the mouse and rat. J Lipid Res 38:1103-1119
    • (1997) J Lipid Res , vol.38 , pp. 1103-1119
    • Hirano, K.1    Min, J.2    Funahashi, T.3    Davidson, N.O.4
  • 40
    • 0028333746 scopus 로고
    • Double replacement: Strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells
    • Wu H, Liu X, Jaenisch R 1994 Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells. Proc Natl Acad Sci USA 91:2819-2823
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2819-2823
    • Wu, H.1    Liu, X.2    Jaenisch, R.3
  • 42
    • 0022467893 scopus 로고
    • Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies
    • Hossenlopp P, Seurin D, Segovia-Quinson B, Hardouin S, Binoux M 1986 Analysis of serum insulin-like growth factor binding proteins using Western blotting: use of the method for titration of the binding proteins and competitive binding studies. Anal Biochem 154:138-143
    • (1986) Anal Biochem , vol.154 , pp. 138-143
    • Hossenlopp, P.1    Seurin, D.2    Segovia-Quinson, B.3    Hardouin, S.4    Binoux, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.