Identification of damaged proteins in human serum using modified Ehrlich's reagent to target protein-bound pyrroles

Analytical Biochemistry

Volumn 398, Issue 1, 2010, Pages 76-82

  Campbell, Fiona M ^a   Rucklidge, Garry J ^a   Reid, Martin D ^a   Cantlay, Louise ^a   Robins, Simon P ^a  

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

Author keywords

Detection of damaged proteins; Modified Ehrlich's reagent; Protein oxidation; Protein bound pyrroles; Proteomics

Indexed keywords

COENZYMES; PROTEOMICS; REAGENTS;

AFTER-TREATMENT; CARDIO-VASCULAR DISEASE; HUMAN CONDITIONS; HUMAN SERUM PROTEINS; OXIDATIVE DAMAGE; OXIDIZING AGENTS; PROTEIN OXIDATION; PROTEOMIC TECHNIQUES;

DAMAGE DETECTION;

4 DIMETHYLAMINOBENZALDEHYDE; BIOLOGICAL MARKER; BIOTIN; OXIDIZING AGENT; PLASMA PROTEIN; PROTEIN; PYRROLE DERIVATIVE;

ARTICLE; ASSAY; BLOTTING; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; HEALTH STATUS; HUMAN; LIQUID CHROMATOGRAPHY; OBESITY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEOMICS; SERUM; TANDEM MASS SPECTROMETRY;

EID: 73549101078     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.11.021     Document Type: Article

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