메뉴 건너뛰기




Volumn 7, Issue 4, 2009, Pages 245-254

A comparison of costs among patients with type 2 diabetes mellitus who initiated therapy with exenatide or insulin glargine

Author keywords

[No Author keywords available]

Indexed keywords

EXENDIN 4; INSULIN GLARGINE; ORAL ANTIDIABETIC AGENT;

EID: 73549100870     PISSN: 11755652     EISSN: 11791896     Source Type: Journal    
DOI: 10.2165/11318730-000000000-00000     Document Type: Article
Times cited : (14)

References (42)
  • 1
    • 43449108812 scopus 로고    scopus 로고
    • Economic costs of diabetes in the US in 2007
    • American Diabetes Association. [ published erratum appears in Diabetes Care 2008; 31 (6): 1271]
    • American Diabetes Association. Economic costs of diabetes in the US in 2007 [published erratum appears in Diabetes Care 2008; 31 (6): 1271]. Diabetes Care 2008; 31: 596-615
    • (2008) Diabetes Care , vol.31 , pp. 596-615
  • 2
    • 40249120466 scopus 로고    scopus 로고
    • Standards of medical care in diabetes: 2008
    • American Diabetes Association.
    • American Diabetes Association. Standards of medical care in diabetes: 2008. Diabetes Care 2008; 31 Suppl. 1: S12-54
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL.1
  • 3
    • 41549084698 scopus 로고    scopus 로고
    • Third-line agent selection for patients with type 2 diabetes mellitus uncontrolled with sulfonylureas and metformin
    • Edwards KL, Alvarez C, Irons BK, et al. Third-line agent selection for patients with type 2 diabetes mellitus uncontrolled with sulfonylureas and metformin. Pharmacotherapy 2008; 28 (4): 506-521
    • (2008) Pharmacotherapy , vol.28 , Issue.4 , pp. 506-521
    • Edwards, K.L.1    Alvarez, C.2    Irons, B.K.3
  • 4
    • 0346724642 scopus 로고    scopus 로고
    • Insulin glargine: Long acting basal insulin analog for improved metabolic control
    • Gerich JE. Insulin glargine: long acting basal insulin analog for improved metabolic control. Curr Med Res Opin 2004; 20: 31-37
    • (2004) Curr Med Res Opin , vol.20 , pp. 31-37
    • Gerich, J.E.1
  • 5
    • 73549098713 scopus 로고    scopus 로고
    • Aventis Pharmaceuticals' LANTUS- (insulin glargine [rDNA origin] injection) approved by FDA for treatment of diabetes
    • BNET. [online]. Available from URL: [Accessed 2008 Sep 23]
    • BNET. Aventis Pharmaceuticals' LANTUS- (insulin glargine [rDNA origin] injection) approved by FDA for treatment of diabetes. Market Wire [online]. Available from URL: http://findarticles.com/p/articles/mi-pwwi/is-200004/ai- mark09008855 [Accessed 2008 Sep 23]
    • Market Wire
  • 6
    • 43449086375 scopus 로고    scopus 로고
    • [online]. Available from URL: [Accessed 2008 Sep 23]
    • US Food and Drug Administration. CDER drug and biologic approvals for calendar year 2005 [online]. Available from URL: http://www.fda.gov/cder/rdmt/ InternetNDA 05.htm [Accessed 2008 Sep 23]
    • (2005) CDER Drug and Biologic Approvals for Calendar Year
  • 7
    • 84868351074 scopus 로고    scopus 로고
    • Exenatide approved for type 2 diabetes: An expert interview with John B. Buse
    • [online]. Available fromURL: [Accessed 2008 Sep 23]
    • Barclay L. Exenatide approved for type 2 diabetes: an expert interview with John B. Buse. Medscape Today [online]. Available fromURL: http://www.medscape.com/viewarticle/ 504227 [Accessed 2008 Sep 23]
    • Medscape Today
    • Barclay, L.1
  • 8
    • 67649373364 scopus 로고    scopus 로고
    • Effects of exenatide on diabetes, obesity, cardiovascular risk factors, and hepatic biomarkers in patients with type 2 diabetes
    • Nielsen LL, Okerson T, Holcombe J, et al. Effects of exenatide on diabetes, obesity, cardiovascular risk factors, and hepatic biomarkers in patients with type 2 diabetes. J Diab Sci Tech 2008; 2: 255-260
    • (2008) J Diab Sci Tech , vol.2 , pp. 255-260
    • Nielsen, L.L.1    Okerson, T.2    Holcombe, J.3
  • 9
    • 34249332073 scopus 로고    scopus 로고
    • Emerging therapies for type 2 diabetes
    • Stonehouse AH, Maggs DG. Emerging therapies for type 2 diabetes. Curr Drug Ther 2007; 2: 151-160
    • (2007) Curr Drug Ther , vol.2 , pp. 151-160
    • Stonehouse, A.H.1    Maggs, D.G.2
  • 10
    • 4344713643 scopus 로고    scopus 로고
    • Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucosedependent insulin secretion and counterregulation during hypoglycemia
    • Degn KB, Brock B, Juhl CB, et al. Effect of intravenous infusion of exenatide (synthetic exendin-4) on glucosedependent insulin secretion and counterregulation during hypoglycemia. Diabetes 2004; 53: 2397-2403
    • (2004) Diabetes , vol.53 , pp. 2397-2403
    • Degn, K.B.1    Brock, B.2    Juhl, C.B.3
  • 11
    • 0036959991 scopus 로고    scopus 로고
    • Effects of glucagon- like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
    • Nauck MA, Heimesaat MM, Behle K, et al. Effects of glucagon- like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin EndocrinolMetab 2002; 87: 1239-1246
    • (2002) J Clin EndocrinolMetab , vol.87 , pp. 1239-1246
    • Nauck, M.A.1    Heimesaat, M.M.2    Behle, K.3
  • 12
    • 34247232203 scopus 로고    scopus 로고
    • Exenatide: A review of its use in patients with type 2 diabetes mellitus (as an adjunct to metformin and/or a sulfonylurea)
    • Cvetkovic RS, Plosker GL. Exenatide: a review of its use in patients with type 2 diabetes mellitus (as an adjunct to metformin and/or a sulfonylurea). Drugs 2007; 67: 935-954
    • (2007) Drugs , vol.67 , pp. 935-954
    • Cvetkovic, R.S.1    Plosker, G.L.2
  • 13
    • 15444367142 scopus 로고    scopus 로고
    • Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus
    • Kolterman OG, Kim DD, Shen L, et al. Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus. Am J Health Syst Pharm 2005; 62: 173-181
    • (2005) Am J Health Syst Pharm , vol.62 , pp. 173-181
    • Kolterman, O.G.1    Kim, D.D.2    Shen, L.3
  • 14
    • 26944477362 scopus 로고    scopus 로고
    • Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes
    • Heine RJ, Van Gaal LF, Johns D, et al. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes. Annals Int Med 2005; 143: 559-569
    • (2005) Annals Int Med , vol.143 , pp. 559-569
    • Heine, R.J.1    Van Gaal, L.F.2    Johns, D.3
  • 15
    • 37349008890 scopus 로고    scopus 로고
    • Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: A multinational, randomized, open-label, two-period, crossover noninferiority trial
    • Barnett AH, Burger J, Johns D, et al. Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial. Clin Ther 2007; 29: 2333-2348
    • (2007) Clin Ther , vol.29 , pp. 2333-2348
    • Barnett, A.H.1    Burger, J.2    Johns, D.3
  • 16
    • 36049005288 scopus 로고    scopus 로고
    • Short-term economic impact of body weight change among patients with type 2 diabetes treated with antidiabetic agents: Analysis using claims, laboratory, and medical record data
    • Yu AP, Wu EQ, Birnbaum HG, et al. Short-term economic impact of body weight change among patients with type 2 diabetes treated with antidiabetic agents: analysis using claims, laboratory, and medical record data. Curr Med Res Opin 2007; 23 (9): 2157-2169
    • (2007) Curr Med Res Opin , vol.23 , Issue.9 , pp. 2157-2169
    • Yu, A.P.1    Wu, E.Q.2    Birnbaum, H.G.3
  • 17
    • 33646877246 scopus 로고    scopus 로고
    • Epidemiology, trends, and morbidities of obesity and the metabolic syndrome
    • Bray GA, Bellanger T. Epidemiology, trends, and morbidities of obesity and the metabolic syndrome. Endocrine 2006; 29: 109-117
    • (2006) Endocrine , vol.29 , pp. 109-117
    • Bray, G.A.1    Bellanger, T.2
  • 18
    • 0037223174 scopus 로고    scopus 로고
    • Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
    • Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA 2003; 289: 76-79
    • (2003) JAMA , vol.289 , pp. 76-79
    • Mokdad, A.H.1    Ford, E.S.2    Bowman, B.A.3
  • 20
    • 0033807248 scopus 로고    scopus 로고
    • Intentional weight loss and mortality among overweight individuals with diabetes
    • Williamson DF, Thompson TJ, Thun M, et al. Intentional weight loss and mortality among overweight individuals with diabetes. Diabetes Care 2000; 23: 1499-1504
    • (2000) Diabetes Care , vol.23 , pp. 1499-1504
    • Williamson, D.F.1    Thompson, T.J.2    Thun, M.3
  • 21
    • 26944477362 scopus 로고    scopus 로고
    • Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: A randomized trial
    • Heine RJ, Van Gaal LF, Johns D, et al. Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial. Ann Intern Med 2005; 143 (8): 559-569
    • (2005) Ann Intern Med , vol.143 , Issue.8 , pp. 559-569
    • Heine, R.J.1    Van Gaal, L.F.2    Johns, D.3
  • 22
    • 34250195737 scopus 로고    scopus 로고
    • Health care resource utilization and expenditures associated with the use of insulin glargine
    • Miller DR, Gardner JA, Hendricks AM, et al. Health care resource utilization and expenditures associated with the use of insulin glargine. Clin Ther 2007; 29 (3): 478-487
    • (2007) Clin Ther , vol.29 , Issue.3 , pp. 478-487
    • Miller, D.R.1    Gardner, J.A.2    Hendricks, A.M.3
  • 23
    • 9744219756 scopus 로고    scopus 로고
    • Systematic review and economic evaluation of a long-acting insulin analogue, insulin glargine
    • Nov
    • Warren E, Weatherley-Jones E, Chilcott J, et al. Systematic review and economic evaluation of a long-acting insulin analogue, insulin glargine. Health Technol Assess 2004 Nov; 8 (45): 1-57
    • (2004) Health Technol Assess , vol.8 , Issue.45 , pp. 1-57
    • Warren, E.1    Weatherley-Jones, E.2    Chilcott, J.3
  • 24
    • 73549098496 scopus 로고    scopus 로고
    • Pharmacoeconomic aspects of use of insulin glargine in treatment of diabetes mellitus type 2 (dm t2) in Russia
    • [abstract]
    • Suntsov YI, Dedov II, Komarova VP, et al. Pharmacoeconomic aspects of use of insulin glargine in treatment of diabetes mellitus type 2 (dm t2) in Russia [abstract]. Value Health 2004; 7: 738
    • (2004) Value Health , vol.7 , pp. 738
    • Suntsov, Y.I.1    Dedov, I.I.2    Komarova, V.P.3
  • 25
    • 43749115146 scopus 로고    scopus 로고
    • Biphasic insulin aspart 70/30 vs insulin glargine in insulin naive type 2 diabetes patients: Modelling the long-term health economic implications in a Swedish setting
    • Jun
    • Goodall G, Jendle JH, Valentine WJ, et al. Biphasic insulin aspart 70/30 vs insulin glargine in insulin naive type 2 diabetes patients: modelling the long-term health economic implications in a Swedish setting. Int J Clin Pract 2008 Jun; 62 (6): 869-876
    • (2008) Int J Clin Pract , vol.62 , Issue.6 , pp. 869-876
    • Goodall, G.1    Jendle, J.H.2    Valentine, W.J.3
  • 26
    • 42149135625 scopus 로고    scopus 로고
    • Economic evaluation of the treatment of type 2 diabetes with insulin glargine based on the LAPTOP trial
    • May
    • Janka HU, Högy B. Economic evaluation of the treatment of type 2 diabetes with insulin glargine based on the LAPTOP trial. Eur J Health Econ 2008 May; 9 (2): 165-170
    • (2008) Eur J Health Econ , vol.9 , Issue.2 , pp. 165-170
    • Janka, H.U.1    Högy, B.2
  • 27
    • 58149346043 scopus 로고    scopus 로고
    • Is the use of insulin analogues cost-effective?
    • Jul-Aug
    • Leichter S. Is the use of insulin analogues cost-effective? Adv Ther 2008 Jul-Aug; 25 (4): 285-299
    • (2008) Adv Ther , vol.25 , Issue.4 , pp. 285-299
    • Leichter, S.1
  • 28
    • 33845515729 scopus 로고    scopus 로고
    • Insulin therapy in type 2 diabetes patients failing oral agents: Cost-effectiveness of biphasic insulin aspart 70/30 vs. insulin glargine in the US
    • DOI 10.1111/j.1463-1326.2006.00581.x
    • Ray JA, Valentine WJ, Roze S, et al. Insulin therapy in type 2 diabetes patients failing oral agents: cost-effectiveness of biphasic insulin aspart 70/30 vs insulin glargine in the US. Diabetes Obes Metab 2007 Jan; 9 (1): 103-113 (Pubitemid 44921048)
    • (2007) Diabetes, Obesity and Metabolism , vol.9 , Issue.1 , pp. 103-113
    • Ray, J.A.1    Valentine, W.J.2    Roze, S.3    Nicklasson, I.4    Cobden, D.5    Raskin, P.6    Garber, A.7    Palmer, A.J.8
  • 29
    • 26444537458 scopus 로고    scopus 로고
    • Insulin glargine in combination with oral antidiabetic drugs as a costequivalent alternative to conventional insulin therapy in type 2 diabetes mellitus
    • Sep
    • Lechleitner M, Roden M, Haehling E, et al. Insulin glargine in combination with oral antidiabetic drugs as a costequivalent alternative to conventional insulin therapy in type 2 diabetes mellitus. Wien Klin Wochenschr 2005 Sep; 117 (17): 593-598
    • (2005) Wien Klin Wochenschr , vol.117 , Issue.17 , pp. 593-598
    • Lechleitner, M.1    Roden, M.2    Haehling, E.3
  • 30
    • 29144462668 scopus 로고    scopus 로고
    • Long-term clinical and cost outcomes of treatment with biphasic insulin aspart 30/70 versus insulin glargine in insulin naive type 2 diabetes patients: Cost-effectiveness analysis in the UK setting
    • Dec
    • Valentine WJ, Palmer AJ, Lammert M, et al. Long-term clinical and cost outcomes of treatment with biphasic insulin aspart 30/70 versus insulin glargine in insulin naive type 2 diabetes patients: cost-effectiveness analysis in the UK setting. Curr Med Res Opin 2005 Dec; 21 (12): 2063-2071
    • (2005) Curr Med Res Opin , vol.21 , Issue.12 , pp. 2063-2071
    • Valentine, W.J.1    Palmer, A.J.2    Lammert, M.3
  • 31
    • 35349026261 scopus 로고    scopus 로고
    • Health care costs of adults treated for attention-deficit/hyperactivity disorder who received alternative drug therapies
    • Wu EQ, Birnbaum HG, Zhang HF, et al. Health care costs of adults treated for attention-deficit/hyperactivity disorder who received alternative drug therapies. J Manag Care Pharm 2007; 13: 561-569
    • (2007) J Manag Care Pharm , vol.13 , pp. 561-569
    • Wu, E.Q.1    Birnbaum, H.G.2    Zhang, H.F.3
  • 32
    • 60749102464 scopus 로고    scopus 로고
    • Direct medical costs for type 2 diabetes mellitus complications in the US commercial payer setting: A resource for economic research
    • Pelletier EM, Smith PJ, Boye KS, et al. Direct medical costs for type 2 diabetes mellitus complications in the US commercial payer setting: a resource for economic research. Appl Health Econ Health Policy 2008; 6 (2-3); 103-112
    • (2008) Appl Health Econ Health Policy , vol.6 , Issue.2-3 , pp. 103-112
    • Pelletier, E.M.1    Smith, P.J.2    Boye, K.S.3
  • 33
    • 0037640620 scopus 로고    scopus 로고
    • Prevalence and costs of major depression among elderly claimants with diabetes
    • Finkelstein EA, Bray JW, Chen H, et al. Prevalence and costs of major depression among elderly claimants with diabetes. Diabetes Care 2003; 26: 415-420
    • (2003) Diabetes Care , vol.26 , pp. 415-420
    • Finkelstein, E.A.1    Bray, J.W.2    Chen, H.3
  • 34
    • 0027133523 scopus 로고
    • Risk adjustment in outcome assessment: The Charlson comorbidity index
    • D'Hoore W, Sicotte C, Tilquin C. Risk adjustment in outcome assessment: the Charlson comorbidity index. Methods Inf Med 1993; 32: 382-387
    • (1993) Methods Inf Med , vol.32 , pp. 382-387
    • D'Hoore, W.1    Sicotte, C.2    Tilquin, C.3
  • 35
    • 51949111620 scopus 로고
    • Smearing estimate: A nonparametric retransformation method
    • Duan N. Smearing estimate: a nonparametric retransformation method. J Am Stat Assoc 1983; 78 (383): 605-610
    • (1983) J Am Stat Assoc , vol.78 , Issue.383 , pp. 605-610
    • Duan, N.1
  • 36
    • 0033009724 scopus 로고    scopus 로고
    • Methods for analyzing health care utilization and costs
    • Diehr P, Yanez D, Ash A, et al. Methods for analyzing health care utilization and costs. Annu Rev Public Health 1999; 20: 125-144
    • (1999) Annu Rev Public Health , vol.20 , pp. 125-144
    • Diehr, P.1    Yanez, D.2    Ash, A.3
  • 37
    • 84952495715 scopus 로고
    • A comparison of alternative models for the demand for medical care
    • Duan N, Manning WG, Morris CN, et al. A comparison of alternative models for the demand for medical care. J Bus Econ Stat 1983; 1: 115-126
    • (1983) J Bus Econ Stat , vol.1 , pp. 115-126
    • Duan, N.1    Manning, W.G.2    Morris, C.N.3
  • 38
    • 33947400120 scopus 로고    scopus 로고
    • Exenatide versus insulin glargine in patients with type 2 diabetes in the UK: A model of long-term clinical and cost outcomes
    • Mar
    • Ray JA, Boye KS, Yurgin N, et al. Exenatide versus insulin glargine in patients with type 2 diabetes in the UK: a model of long-term clinical and cost outcomes. Curr Med Res Opin 2007 Mar; 23 (3): 609-622
    • (2007) Curr Med Res Opin , vol.23 , Issue.3 , pp. 609-622
    • Ray, J.A.1    Boye, K.S.2    Yurgin, N.3
  • 39
    • 33144490068 scopus 로고    scopus 로고
    • The association between diabetes related medical costs and glycemic control: A retrospective analysis
    • Oglesby AK, Secnik K, Barron J, et al. The association between diabetes related medical costs and glycemic control: a retrospective analysis. Cost Eff Resour Alloc 2006; 4: 1
    • (2006) Cost Eff Resour Alloc , vol.4 , pp. 1
    • Oglesby, A.K.1    Secnik, K.2    Barron, J.3
  • 40
    • 27744441934 scopus 로고    scopus 로고
    • Relationship of glycemic control to total diabetes-related costs for managed care health plan members with type 2 diabetes
    • Shetty S, Secnik K, Oglesby AK. Relationship of glycemic control to total diabetes-related costs for managed care health plan members with type 2 diabetes. J Manag Care Pharm 2005; 11 (7): 559-564
    • (2005) J Manag Care Pharm , vol.11 , Issue.7 , pp. 559-564
    • Shetty, S.1    Secnik, K.2    Oglesby, A.K.3
  • 41
    • 0028100191 scopus 로고
    • Knowledge and practices of generalist and specialist physicians regarding drug therapy for acute myocardial infarction
    • Oct 27
    • Ayanian JZ, Hauptman PJ, Guadagnoli E, et al. Knowledge and practices of generalist and specialist physicians regarding drug therapy for acute myocardial infarction. N Engl J Med 1994 Oct 27; 331 (17): 1136-1142
    • (1994) N Engl J Med , vol.331 , Issue.17 , pp. 1136-1142
    • Ayanian, J.Z.1    Hauptman, P.J.2    Guadagnoli, E.3
  • 42
    • 84868377434 scopus 로고    scopus 로고
    • [online]. Available from URL: [Accessed 2008 Sep 23]
    • i3. Data assets: better data matters [online]. Available from URL: http://www.i3global.com/DataAssets/ [Accessed 2008 Sep 23]
    • Data Assets: Better Data Matters


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.