A fluorescent polarization-based assay for the identification of disruptors of the RCAN1-calcineurin A protein complex

Analytical Biochemistry

Volumn 398, Issue 1, 2010, Pages 99-103

  Carme Mulero, M ^a   Orzáez, Mar ^b   Messeguer, Joaquim ^c   Messeguer, Ángel ^c   Pérez Payá, Enrique ^b,d   Pérez Riba, Mercè ^a  

^a BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^b CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^c INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^d INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

Author keywords

Calcineurin A; Fluorescence polarization assay; Immunosuppression; Millipolarization units; NFAT; RCAN1

Indexed keywords

AMINO ACIDS; DRUG INTERACTIONS; FLUORESCENCE; MOLECULES; PHOSPHATASES; T-CELLS; TRANSCRIPTION;

CALCINEURIN; FLUORESCENCE POLARIZATION; IMMUNOSUPPRESSION; MILLIPOLARIZATION UNITS; NFAT; RCAN1;

POLARIZATION;

CALCINEURIN; CALCINEURIN A; DIPYRIDAMOLE; IMMUNOSUPPRESSIVE AGENT; PROTEIN RCAN1; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FLUORESCENCE POLARIZATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION;

EID: 73549094686     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2009.10.045     Document Type: Article

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