Plasma oxidized low-density lipoprotein levels and arterial stiffness in older adults the health, aging, and body composition study

Hypertension

Volumn 53, Issue 5, 2009, Pages 846-852

  Brinkley, Tina E ^a   Nicklas, Barbara J ^a   Kanaya, Alka M ^b   Satterfield, Suzanne ^c   Lakatta, Edward G ^d   Simonsick, Eleanor M ^d   Sutton Tyrrell, Kim ^e   Kritchevsky, Stephen B ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^d NATIONAL INSTITUTE ON AGING   (United States)

^e UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Aging; Aortic stiffness; Epidemiology; Oxidative stress; Pulse wave velocity

Indexed keywords

HEMOGLOBIN A1C; OXIDIZED LOW DENSITY LIPOPROTEIN;

AGED; AGING; ARTERIAL STIFFNESS; ARTICLE; ATHEROSCLEROSIS; BODY COMPOSITION; CARDIOVASCULAR RISK; FEMALE; HUMAN; INTRAABDOMINAL FAT; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSE WAVE;

AGED; AGING; AORTA; BLOOD FLOW VELOCITY; BODY COMPOSITION; FEMALE; HUMANS; LIPOPROTEINS, LDL; LOGISTIC MODELS; MALE;

EID: 73549092297     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.108.127043     Document Type: Article

References (48)

1. Lakatta EG, Levy D. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part I: aging arteries: a "set up" for vascular disease. Circulation. 2003;107:139-146.
2. 2. Lakatta EG. Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part III: cellular and molecular clues to heart and arterial aging. Circulation. 2003;107:490-497. (Pubitemid 36158054)
3. 3. Dao HH, Essalihi R, Bouvet C, Moreau P. Evolution and modulation of age-related medial elastocalcinosis: impact on large artery stiffness and isolated systolic hypertension. Cardiovasc Res. 2005;66:307-317. (Pubitemid 40471045)
4. 4. O'Rourke MF, Hashimoto J. Mechanical factors in arterial aging: a clinical perspective. J Am Coll Cardiol. 2007;50:1-13. (Pubitemid 46963521)
5. 5. Blacher J, Safar ME, Guerin AP, Pannier B, Marchais SJ, London GM. Aortic pulse wave velocity index and mortality in end-stage renal disease. Kidney Int. 2003;63:1852-1860. (Pubitemid 36513333)
6. 6. Chen YT, Vaccarino V, Williams CS, Butler J, Berkman LF, Krumholz HM. Risk factors for heart failure in the elderly: a prospective community-based study. Am J Med. 1999;106:605-612. (Pubitemid 29279295)
7. 7. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, Ducimetiere P, Benetos A. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension. 2001;37:1236-1241. (Pubitemid 34163575)
8. 8. Laurent S, Katsahian S, Fassot C, Tropeano AI, Gautier I, Laloux B, Boutouyrie P. Aortic stiffness is an independent predictor of fatal stroke in essential hypertension. Stroke. 2003;34:1203-1206. (Pubitemid 36547514)
9. 9. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, Asmar R, Reneman RS, Hoeks AP, Breteler MM, Witteman JC. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation. 2006;113:657-663. (Pubitemid 43754329)
10. 10. Sutton-Tyrrell K, Najjar SS, Boudreau RM, Venkitachalam L, Kupelian V, Simonsick EM, Havlik R, Lakatta EG, Spurgeon H, Kritchevsky S, Pahor M, Bauer D, Newman A. Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in wellfunctioning older adults. Circulation. 2005;111:3384-3390. (Pubitemid 40923391)
11. 11. Nedeljkovic ZS, Gokce N, Loscalzo J. Mechanisms of oxidative stress and vascular dysfunction. Postgrad Med J. 2003;79:195-199. (Pubitemid 36605780)
12. Stocker R, Keaney JF Jr. Role of oxidative modifications in atherosclerosis. Physiol Rev. 2004;84:1381-1478.
13. 13. Holvoet P, Harris TB, Tracy RP, Verhamme P, Newman AB, Rubin SM, Simonsick EM, Colbert LH, Kritchevsky SB. Association of high coronary heart disease risk status with circulating oxidized LDL in the well-functioning elderly: findings from the Health, Aging, and Body Composition Study. Arterioscler Thromb Vase Biol. 2003;23:1444-1448. (Pubitemid 36994534)
14. 14. Holvoet P, Jenny NS, Schreiner PJ, Tracy RP, Jacobs DR. The relationship between oxidized LDL and other cardiovascular risk factors and subclinical CVD in different ethnic groups: the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 2007;194:245-252. (Pubitemid 47464304)
15. 15. Hulthe J, Fagerberg B. Circulating oxidized LDL is associated with subclinical atherosclerosis development and inflammatory cytokines (AIR Study). Arterioscler Thromb Vase Biol. 2002;22:1162-1167. (Pubitemid 34764868)
16. Jimi S, Saku K, Uesugi N, Sakata N, Takebayashi S. Oxidized low density lipoprotein stimulates collagen production in cultured arterial smooth muscle cells. Atherosclerosis. 1995;116:15-26.
17. Matthys KE, Van Hove CE, Kockx MM, Andries LJ, Van ON, Herman AG, BuIt H. Local application of LDL promotes intimai thickening in the collared carotid artery of the rabbit. Arterioscler Thromb Vase Biol. 1997;17:2423-2429.
18. Fleming I, Mohamed A, Galle J, Turchanowa L, Brandes RP, Fisslthaler B, Busse R. Oxidized low-density lipoprotein increases superoxide production by endothelial nitric oxide synthase by inhibiting PKCalpha. Cardiovasc Res. 2005;65:897-906. (Pubitemid 40249734)
19. 19. Hein TW, Liao JC, Kuo L. OxLDL specifically impairs endotheliumdependent, NO-mediated dilation of coronary arterioles. Am J Physiol Heart Circ Physiol. 2000;278:H175-H183. (Pubitemid 30101869)
20. 20. Thomas SR, Chen K, Keaney JF Jr. Oxidative stress and endothelial nitric oxide bioactivity. Antioxid Redox Signal. 2003;5:181-194. (Pubitemid 36457594)
21. 21. Toikka JO, Niemi P, Ahotupa M, Niinikoski H, Viikari J S, Ronnemaa T, Hartiala JJ, Raitakari OT. Large-artery elastic properties in young men: relationships to serum lipoproteins and oxidized low-density lipoproteins. Arterioscler Thromb Vase Biol. 1999;19:436-441. (Pubitemid 29072761)
22. 22. Noma K, Goto C, Nishioka K, Jitsuiki D, Umemura T, Ueda K, Kimura M, Nakagawa K, Oshima T, Chayama K, Yoshizumi M, Liao JK, Higashi Y. Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness. J Am Coll Cardiol. 2007;49:698-705. (Pubitemid 46205044)
23. 23. Brach JS, Simonsick EM, Kritchevsky S, Yaffe K, Newman AB. The association between physical function and lifestyle activity and exercise in the health, aging and body composition study. J Am Geriatr Soc. 2004;52:502-509. (Pubitemid 38480625)
24. Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
25. 25. Sutton-Tyrrell K, Newman A, Simonsick EM, Havlik R, Pahor M, Lakatta E, Spurgeon H, Vaitkevicius P. Aortic stiffness is associated with visceral adiposity in older adults enrolled in the study of health, aging, and body composition. Hypertension. 2001;38:429-433. (Pubitemid 34225678)
26. 26. Holvoet P, Vanhaecke J, Janssens S, Van de WF, Collen D. Oxidized LDL and malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease. Circulation. 1998;98: 1487-1494. (Pubitemid 28481664)
27. 27. Holvoet P, Van CJ, Collen D, Vanhaecke J. Oxidized low density lipoprotein is a prognostic marker of transplant-associated coronary artery disease. Arterioscler Thromb Vase Biol. 2000;20:698-702. (Pubitemid 30151683)
28. 28. Holvoet P, Mertens A, Verhamme P, Bogaerts K, Beyens G, Verhaeghe R, Collen D, Muls E, Van de WF. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vase Biol. 2001;21:844-848. (Pubitemid 32448777)
29. Van Berkel TJ, De Rijke YB, Kruijt JK. Different fate in vivo of oxidatively modified low density lipoprotein and acetylated low density lipoprotein in rats. Recognition by various scavenger receptors on Kupffer and endothelial liver cells. J Biol Chem. 1991;266:2282-2289.
30. 30. De Rijke YB, Biessen EA, Vogelezang CJ, Van Berkel TJ. Binding characteristics of scavenger receptors on liver endothelial and Kupffer cells for modified low-density lipoproteins. Biochem J. 1994;304:69-73. (Pubitemid 24354226)
31. 31. Meisinger C, Baumert J, Khuseyinova N, Loewel H, Koenig W. Plasma oxidized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle-aged men from the general population. Circulation. 2005;112:651-657. (Pubitemid 41099043)
32. 32. Nordin FG, Hedblad B, Berglund G, Nilsson J. Plasma oxidized LDL: a predictor for acute myocardial infarction? J Intern Med. 2003;253: 425-429. (Pubitemid 36418927)
33. 33. Meaume S, Rudnichi A, Lynch A, Bussy C, Sebban C, Benetos A, Safar ME. Aortic pulse wave velocity as a marker of cardiovascular disease in subjects over 70 years old. J Hypertens. 2001;19:871-877. (Pubitemid 32436950)
34. Fernandes VR, Polak JF, Cheng S, Rosen BD, Carvalho B, Nasir K, McClelland R, Hundley G, Pearson G, O'Leary DH, Bluemke DA, Lima JA. Arterial stiffness is associated with regional ventricular systolic and diastolic dysfunction: the Multi-Ethnic Study of Atherosclerosis. Arterioscler Thromb Vase Biol. 2008;28:194-201.
35. Pini R, Cavallini MC, Bencini F, Silvestrini G, Tonon E, De AW, Marchionni N, Di BM, Devereux RB, Masotti G, Roman MJ. Cardiovascular remodeling is greater in isolated systolic hypertension than in diastolic hypertension in older adults: the Insufficienza Cardiaca Negli Anziani Residenti (ICARE) a Dicomano Study. J Am Coll Cardiol. 2002;40:1283-1289.
36. 36. Roman MJ, Ganau A, Saba PS, Pini R, Pickering TG, Devereux RB. Impact of arterial stiffening on left ventricular structure. Hypertension. 2000;36:489-494. (Pubitemid 30778224)
37. Safar ME, Toto-Moukouo JJ, Bouthier JA, Asmar RE, Levenson JA, Simon AC, London GM. Arterial dynamics, cardiac hypertrophy, and antihypertensive treatment. Circulation. 1987;75:I156-I161.
38. 38. Zieman SJ, Melenovsky V, Kass DA. Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vase Biol. 2005;25:932-943. (Pubitemid 40627836)
39. 39. Cai H, Harrison DG Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000;87:840-844. (Pubitemid 30943820)
40. 40. Huang Y, Mironova M, Lopes-Virella MF. Oxidized LDL stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells. Arterioscler Thromb Vase Biol. 1999;19:2640-2647. (Pubitemid 29536038)
41. 41. Xu XP, Meisel SR, Ong JM, Kaul S, Cercek B, Rajavashisth TB, Sharifi B, Shah PK. Oxidized low-density lipoprotein regulates matrix metalloproteinase-9 and its tissue inhibitor in human monocyte-derived macrophages. Circulation. 1999;99:993-998. (Pubitemid 29104486)
42. Chatterjee S. Role of oxidized human plasma low density lipoproteins in atherosclerosis: effects on smooth muscle cell proliferation. Mol Cell Biochem. 1992;111:143-147.
43. 43. Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM. Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci USA. 1990;87: 5134-5138. (Pubitemid 20224287)
44. 44. McMurray HF, Parthasarathy S, Steinberg D. Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes. J Clin Invest. 1993;92:1004-1008. (Pubitemid 23262425)
45. 45. Quinn MT, Parthasarathy S, Fong LG, Steinberg D. Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Natl Acad Sei USA. 1987;84:2995-2998. (Pubitemid 17064764)
46. 46. Rangaswamy S, Penn MS, Saidel GM, Chisolm GM. Exogenous oxidized low-density lipoprotein injures and alters the barrier function of endothelium in rats in vivo. Circ Res. 1997;80:37-44. (Pubitemid 27030366)
47. Bear M, Butcher M, Shaughnessy SG. Oxidized low-density lipoprotein acts synergistically with beta-glycerophosphate to induce osteoblast differentiation in primary cultures of vascular smooth muscle cells. J Cell Biochem. 2008;101:185-193.
48. 48. Cola C, Almeida M, Li D, Romeo F, Mehta JL. Regulatory role of endothelium in the expression of genes affecting arterial calcification. Biochem Biophys Res Commun. 2004;320:424-427. (Pubitemid 38798884)