Monitoring of CD95 and CD38 expression in peripheral blood T lymphocytes during active human cytomegalovirus infection after orthotopic liver transplantation

Journal of Gastroenterology and Hepatology (Australia)

Volumn 25, Issue 1, 2010, Pages 138-142

  Wang, Yuliang ^a,b   Liu, Yawu ^d   Han, Ruifa ^a   Li, Qiang ^a   Yao, Zhi ^a   Niu, Wenyan ^a   Yuan, Yuhua ^c   Tang, Zhiqin ^b   Zhu, Zhijun ^b   Shen, Zhongyang ^b  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b TIANJIN FIRST CENTRAL HOSPITAL   (China)

^c Tianjin Blood Center   (China)

^d KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

CD38; CD95; Cytomegalovirus; Liver transplantation

Indexed keywords

CD38 ANTIGEN; FAS ANTIGEN; GANCICLOVIR;

ADULT; ARTICLE; BLOOD SAMPLING; CD3+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; FEMALE; FLOW CYTOMETRY; GRAFT RECIPIENT; HUMAN; HUMAN CYTOMEGALOVIRUS; LIVER GRAFT; LIVER TRANSPLANTATION; MALE; ORTHOTOPIC TRANSPLANTATION; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 73449148730     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2009.05966.x     Document Type: Article

References (27)

1. Kusne S, Blair JE. Viral and fungal infections after liver transplantation - part II. Liver Transpl. 2006 12 : 2 11.
2. George MJ, Snydman DR, Werner BG et al. The independent role of cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant recipients. Boston Center for Liver Transplantation CMVIG-Study Group. Cytogam, MedImmune, Inc. Gaithersburg, Maryland. Am. J. Med. 1997 103 : 106 113.
3. Nichols WG, Corey L, Gooley T, Davis C, Boeckh M. High risk of death due to bacterial and fungal infection among cytomegalovirus (CMV)-seronegative recipients of stem cell transplants from seropositive donors: evidence for indirect effects of primary CMV infection. J. Infect. Dis. 2002 185 : 273 282.
4. Razonable RR. Cytomegalovirus infection after liver transplantation: current concepts and challenges. World J. Gastroenterol. 2008 14 : 4849 4860.
5. Soccal PM, Doyle RL, Jani A et al. Quantification of cytotoxic T-cell gene transcripts in human lung transplantation. Transplantation 2000 69 : 1923 1927.
6. Deaglio S, Mehta K, Malavasi F. Human CD38: a (r)evolutionary story of enzymes and receptors. Leuk. Res. 2001 25 : 1 12.
7. Bofill M, Borthwich NJ. CD38 in health and disease. Chem. Immunol. 2000 75 : 218 234.
8. Zidovec Lepej S, Vince A, Dakovic Rode O, Remenar A, Jeren T. Increased numbers of CD38 molecules on bright CD8+ T lymphocytes in infectious mononucleosis caused by Epstein-Barr virus infection. Clin. Exp. Immunol. 2003 133 : 384 390.
9. Lechner F, Gruener NH, Urbani S et al. CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained. Eur. J. Immunol. 2000 30 : 2479 2487.
10. Al-Harthi L, MaWhinney S, Connick E et al. Immunophenotypic alterations in acute and early HIV infection. Clin. Immunol. 2007 125 : 299 308.
11. Ju ST, Panka DJ, Cui H et al. Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995 373 : 444 448.
12. Akazawa Y, Gores GJ. Death receptor-mediated liver injury. Semin. Liver Dis. 2007 27 : 327 338.
13. Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004 116 : 205 219.
14. Wang Y, Liu Y, Zhang Y et al. The role of the CD95, CD38 and TGFbeta1 during active human cytomegalovirus infection in liver transplantation. Cytokine 2006 35 : 193 199.
15. McCloskey TW, Cavaliere T, Bakshi S et al. Immunophenotyping of T lymphocytes by three-color flow cytometry in healthy newborns, children, and adults. Clin. Immunol. Immunopathol. 1997 84 : 46 55.
16. Benz C, Utermöhlen O, Wulf A et al. Activated virus-specific T cells are early indicators of anti-CMV immune reactions in liver transplant patients. Gastroenterology 2002 122 : 1201 1215.
17. Yang J, Gallagher SF, Haines K et al. Kupffer cell-derived Fas ligand plays a role in liver injury and hepatocyte death. J. Gastrointest. Surg. 2004 8 : 166 174.
18. Mita A, Hashikura Y, Tagawa Y, Nakayama J, Kawakubo M, Miyagawa S. Expression of Fas ligand by hepatic macrophages in patients with fulminant hepatic failure. Am. J. Gastroenterol. 2005 100 : 2551 2559.
19. Marín LA, Muro M, Moya-Quiles MR et al. Study of Fas (CD95) and FasL (CD178) polymorphisms in liver transplant recipients. Tissue Antigens 2006 67 : 117 126.
20. Miyagawa-Hayashino A, Tsuruyama T, Egawa H et al. FasL expression in hepatic antigen-presenting cells and phagocytosis of apoptotic T cells by FasL+ Kupffer cells are indicators of rejection activity in human liver allografts. Am. J. Pathol. 2007 171 : 1499 1508.
21. Raftery MJ, Schwab M, Eibert SM, Samstag Y, Walczak H, Schonrich G. Targeting the function of mature dendritic cells by human cytomegalovirus: a multilayered viral defense strategy. Immunity 2001 15 : 997 1009.
22. Bonfoco E, Stuart PM, Brunner T et al. Inducible nonlymphoid expression of Fas ligand is responsible for superantigen-induced peripheral deletion of T cells. Immunity 1998 9 : 711 720.
23. Zhan HG, Mountz JD, Fleck M, Zhou T, Hsu HC. Specific deletion of autoreactive T cells by adenovirus-transfected, Fas ligand-producing antigen-presenting cells. Immunol. Res. 2002 26 : 235 246.
24. Tannapfel A, Kohlhaw K, Ebelt J et al. Apoptosis and the expression of Fas and Fas ligand (FasL) antigen in rejection and reinfection in liver allograft specimens. Transplantation 1999 67 : 1079 1083.
25. Marin L, Minguela A, Moya-Quiles MR et al. Expression of CD95 and apoptosis induction in peripheral blood cells from liver graft recipients. Transpl. Proc. 2002 34 : 280 282.
26. Rivero M, Crespo J, Mayorga M, Fabrega E, Casafont F, Pons-Romero F. Involvement of the Fas system in liver allograft rejection. Am. J. Gastroenterol. 2002 97 : 1501 1506.
27. Wang YL, Zhang YY, Li G et al. Correlation of CD95 and soluble CD95 expression with acute rejection status of liver transplantation. World J. Gastroenterol. 2005 11 : 1700 1704.