The independent role of cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant recipients

American Journal of Medicine

Volumn 103, Issue 2, 1997, Pages 106-113

  George, Marie J ^a   Snydman, David R ^a   Werner, Barbara G ^c   Griffith, John ^a   Falagas, Matthew E ^a   Dougherty, Nancy N ^c   Rubin, Robert H ^b  

^a TUFTS MEDICAL CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLOTRIMAZOLE; FLUCONAZOLE; NYSTATIN; OKT 3;

ADULT; AGED; ARTICLE; BACTERIUM CULTURE; CYTOMEGALOVIRUS INFECTION; GRAFT SURVIVAL; HUMAN; HUMAN CELL; HUMAN TISSUE; INFECTION RISK; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SERODIAGNOSIS; VIRUS PATHOGENESIS;

EID: 0030792873     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(97)80021-6     Document Type: Article

References (29)

1. Kusne S, Dummer JS, Singh N, et al. Infections after liver transplantation. An analysis of 101 consecutive cases. Medicine. 1988;67:132-143.
2. Wajszczuk CP, Dummer JS, Ho M, et al. Fungal infections in liver transplant recipients. Transplantation. 1985;40:347-353.
3. Castaldo P, Stratta RJ, Wood RP, et al. Clinical spectrum of fungal infections after orthotopic liver transplantation. Arch Surg. 1991;126:149-156.
4. Colonna JO II, Winston DJ, Brill JE, et al. Infectious complications in liver transplantation. Arch Surg. 1988;123:360-364.
5. Castaldo P, Stratta RJ, Wood RP, et al. Fungal disease in liver transplant recipients: A multivariate analysis of risk factors. Transplantation Proceedings. 1991;23:1517-1519.
6. Tollelmar J, Ericzon BG, Barkholt LL, et al. Risk factors for deep candida infection in liver transplant recipients. Transplantation Proceedings. 1990; 22:1826-1827.
7. Winston DJ, Emmanoulides C, Busuttil RW. Infections in liver transplant recipients. Clin Infect Dis. 1995;21:1077-1091.
8. Paya CV, Hermans PE, Washington A, et al. Incidence, distribution, and outcome of episodes of infection in 100 orthotopic liver transplantations. Mayo Clinic Proceedings. 1989;64:555-564.
9. Rand KH, Polland RB, Merigan TC. Increased pulmonary superinfections in cardiac transplant patients undergoing primary cytomegalovirus infection. NEJM. 1978;298:951-953.
10. Chatterjee SN, Fiala M, Weiner J, et al. Primary cytomegalovirus and opportunistic infections. Incidence in renal transplant recipients. JAMA. 1978; 240:2446-2449.
11. Gorensek MJ, Stewart RW, Keys TF, et al. Symptomatic cytomegalovirus infection as a significant risk factor for major infections after cardiac transplantation. J Infect Dis. 1988;158:884-887.
12. Collins LA, Samore MH, Roberts MS, et al. Risk factors for invasive fungal infections complicating orthotopic liver transplantation. J Infect Dis. 1994; 170:644-652.
13. Arend SM, Westendorp RGJ, Kroon FP, et al. Rejection treatment and cytomegalovirus infection as risk factors for Pneumocystis carinii pneumonia in renal transplant recipients. Clin Infect Dis. 1996;22:920-925.
14. Snydman DR, Werner BG, Dougherty NN, et al. Cytomegalovirus immune globulin prophylaxis in liver transplantation. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1993;119:984-991.
15. Hodinka RL, Friedman HM. Human cytomegalovirus. In: Balows A, Hansler WJ Jr, Herrmann KL, et al, eds. Manual of Clinical Microbiology, 5th ed. Washington DC: American Society for Microbiology, 1991:829-837.
16. Gleaves CA, Smith TF, Shuster EA, Pearson GR. Rapid detection of cytomegalovirus in MRC-5 cells inoculated with urine specimens by using low-speed centrifugation and monoclonal antibody to an early antigen. J Clin Microbiol. 1984;19:917-919.
17. Arbo MDJ, Snydman DR. Influence of blood culture results on antibiotic choice in the treatment of bacteremia. Aren Intern Med. 1994;154:2641-2645.
18. Cox DR. Regression models and life tables. J R Statis Soc Series B. 1972;34:187-220.
19. SAS/STAT User's Guide, Version 6, 4th ed., SAS Institute Inc.: Cary, North Carolina; 1990.
20. Wagner JA, Ross H, Hunt S, et al. Prophylactic ganciclovir treatment reduces fungal as well as cytomegalovirus infections after heart transplantation. Transplantation. 1995;60:1473-1477.
21. van den Berg AP, Klompmaker IJ, Haagsma EB, et al. Antigenemia in the diagnosis and monitoring of active cytomegalovirus infection after liver transplantation. J Infect Dis. 1991;164:265-270.
22. Osborn JE, Blazkovec AA, Walker DL Immunosuppression during acute murine cytomegalovirus infection. J Immunol. 1968;100:835-844.
23. Sell MS, Bale JF Jr, Giller RH. T-lymphocyte subpopulations and function during murine cytomegalovirus infection. Pediatric Research. 1985;19:583-587.
24. Schooley RT, Hirsch MS, Colvin RB, et al. Association of herpesvirus infections with T-lymphocyte subset alterations, glomerulopathy, and opportunistic infections after renal transplantation. NEJM. 1983;308:307-313.
25. Dummer JS, Ho M, Rabin B, et al. The effect of cytomegalovirus and Epstein-Barr virus infection on T-lymphocyte subsets in cardiac transplant patients on cytosporine. Transplantation. 1984;38:433-435.
26. Maher P, O'Toole CM, Wreghitt TG, et al. Cytomegalovirus infection in cardiac transplant recipients associated with chronic T cell subset ratio inversion with expansion of a Leu-7+ TS-C+ subset. Clin Exp Immunol. 1985;62:515-524.
27. Linnemann CC Jr, Kaufmann CA, First MR, et al. Cellular immune response to cytomegalovirus infection after renal transplantation. Infect Immun. 1978; 22:176-180.
28. Pollard RB, Arvin AM, Gamberg P, et al. Specific cell-mediated immunity and infections with herpes viruses in cardiac transplant recipients. Am J Med. 1982;73:679-687.
29. Snydman DR, Werner BG, Heinze-Lacey B, et al. Use of cytomegalovirus immune globulin to prevent cytomegalovirus disease in renal-transplant recipients. NEJM. 1987;317:1049-1054.