Salmonella enterica serovar typhimurium trxA mutants are protective against virulent challenge and induce less inflammation than the live-attenuated vaccine strain SL3261

Infection and Immunity

Volumn 78, Issue 1, 2010, Pages 326-336

  Peters, S E ^a   Paterson, G K ^a   Bandularatne, E S D ^a,c   Northen, H C ^a   Pleasance, S ^a   Willers, C ^a   Wang, J ^a   Foote, A K ^a,d   Constantino Casas, F ^a   Scase, T J ^a,e   Blacklaws, B A ^a   Bryant, C E ^a   Mastroeni, P ^a   Charles, I G ^b   Maskell, D J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d Rossdale & Partners   (United Kingdom)

^e Bridge Pathology Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; KANAMYCIN; LIVE VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BACTERIAL INFECTION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM MUTANT; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL INFILTRATION; CONTROLLED STUDY; EXPERIMENT; GENE CASSETTE; GENE DELETION; IMMUNIZATION; INFLAMMATION; LIVER; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SEROTYPE; SPLEEN; SPLENOMEGALY;

ANIMALS; BACTERIAL PROTEINS; INFLAMMATION; INJECTIONS, INTRAVENOUS; LIPOPOLYSACCHARIDES; LIVER; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MUTATION; SALMONELLA INFECTIONS, ANIMAL; SALMONELLA TYPHIMURIUM; SALMONELLA VACCINES; SPLEEN; TIME FACTORS; TOLL-LIKE RECEPTOR 4; VIRULENCE;

EID: 73449139464     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00768-09     Document Type: Article

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