Is increased thrombin activation in patients with abdominal aortic aneurysms dependent on area or volume of aneurysm thrombus mass?

Angiology

Volumn 61, Issue 1, 2010, Pages 113-118

  Kölbel, Tilo ^a   Donath, Tobias ^a   Strandberg, Karin ^a   Flondell Sité, Despina ^a   Kühme, Tobias ^a   Gottsäter, Anders ^a   Lindblad, Bengt ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Abdominal aortic aneurysm; Aneurysm thrombus; Coagulation activation; Thrombin activation

Indexed keywords

ACTIVATED PROTEIN C; PLASMINOGEN ACTIVATOR INHIBITOR 3; THROMBIN;

ABDOMINAL AORTA ANEURYSM; ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FLUOROMETRY; HUMAN; MAJOR CLINICAL STUDY; MALE; MORPHOLOGY; STATISTICAL SIGNIFICANCE; THROMBUS;

AGED; AGED, 80 AND OVER; AORTA, ABDOMINAL; AORTIC ANEURYSM, ABDOMINAL; AORTIC DISEASES; CASE-CONTROL STUDIES; HUMANS; MIDDLE AGED; THROMBIN; THROMBOSIS;

EID: 73449138761     PISSN: 00033197     EISSN: None     Source Type: Journal    
DOI: 10.1177/0003319709335906     Document Type: Article

References (34)

1. Englberger L., Savolainen H., Jandus P., et al. Activated coagulation during open and endovascular abdominal aortic aneurysm repair. J Vasc Surg. 2006 ; 43 (6). 1124-1129.
2. Kölbel T., Strandberg K., Mattiasson I., Stenflo J., Lindblad B. Activated protein C-protein C inhibitor complex: a new biological marker for aortic aneurysms. J Vasc Surg. 2006 ; 43 (6). 935-939.
3. Hosaka A., Miyata T., Aramoto H., et al. Clinical implication of plasma level of soluble fibrin monomer-fibrinogen complex in patients with abdominal aortic aneurysm. J Vasc Surg. 2005 ; 42 (2). 200-205.
4. Ihara A., Kawamoto T., Matsumoto K., et al. Relationship between hemostatic markers and circulating biochemical markers of collagen metabolism in patients with aortic aneurysm. Pathophysiol Haemost Thromb. 2003 ; 33 (4). 221-224.
5. Holmberg A., Siegbahn A., Westman B., Bergqvist D. Ischaemia and reperfusion during open abdominal aortic aneurysm surgery induce extensive thrombin generation and activity. Eur J Vasc Endovasc Surg. 1999 ; 18 (1). 11-16.
6. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005 ; 352 (16). 1685-1695.
7. Lowe GDO. Different locations of atherosclerosis- different risk factors, different therapies? Pathophysiol Haemost Thromb. 2003 ; 33 (5-6). 262-267.
8. Marutsuka K., Hatakeyama K., Yamashita A., Asada Y. Role of thrombogenic factors in the development of atherosclerosis. J Atheroscler Thromb. 2005 ; 12 (1). 1-8.
9. Cassar K., Bachoo P., Ford I., Greaves M., Brittenden J. Markers of coagulation activation, endothelial stimulation and inflammation in patients with peripheral arterial disease. Eur J Vasc Endovasc Surg. 2005 ; 29 (2). 171-176.
10. Corti R., Farkouh ME, Badimon JJ The vulnerable plaque and acute coronary syndromes. Am J Med. 2002 ; 113 (8). 668-680.
11. Ananyeva NM, Kouiavskaia DV, Shima M., Saenko EL Intrinsic pathway of blood coagulation contributes to thrombogenicity of atherosclerotic plaque. Blood. 2002 ; 99 (12). 4475-4485.
12. Sofi F., Lari B., Rogolino A., et al. Thrombophilic risk factors for symptomatic peripheral artery disease. J Vasc Surg. 2005 ; 41 (2). 255-260.
13. Lusis AJ Atherosclerosis. Nature. 2000 ; 68 (1). 407: 233-241.
14. Strandberg K., Kjellberg M., Knebel R., Lilja H., Stenflo J. A sensitive immunochemical assay for measuring the concentration of the activated protein C-protein C inhibitor complex in plasma. Thromb Haemost. 2001 ; 86 (2). 604-610.
15. Strandberg K., Svensson A., Stenflo J. Stabilyte tubes that contain strongly acidic citrate prevent in vitro complex formation between activated protein C and protein C inhibitor. Thromb Haemost. 2003 ; 89 (5). 947-949.
16. Kölbel T., Strandberg K., Donath T., Mattiasson I., Stenflo J., Lindblad B. Thrombin activation in patients with abdominal aortic aneurysms-is it associated with diameter and growth rate ? Vasc Endovascular Surg. 2008 ; 42 (2). 135-140.
17. Shindo S., Matsumoto H., Kubota K., et al. Is the size of an abdominal aortic aneurysm associated with coagulopathy ? World J Surg. 2005 ; 29 (7). 925-929.
18. Lindblad B., Börner G., Gottsäter A. Factors associated with development of large abdominal aortic aneurysm in middle-aged men. Eur J Vasc Endovasc Surg. 2005 ; 30 (4). 346-352.
19. Alcorn HG, Wolfson SK Jr, Sutton-Tyrrell K., Kuller LH, OLeary D. Risk factors for abdominal aortic aneurysms in older adults enrolled in the cardiovascular health study. Arterioscler Thromb Vasc Biol. 1996 ; 16 (8). 963-970.
20. Lederle FA, Johnson GR, Wilson SE, et al. Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm detection and management (ADAM) Veterans affair cooperative study group. Ann Intern Med. 1997 ; 126 (6). 441-449.
21. Wassef M., Baxter BT, Chisholm RL, et al. Pathogenesis of abdominal aortic aneurysms: a multidisciplinary research program supported by the National Heart, Lung, and Blood Institute. J Vasc Surg. 2001 ; 34 (4). 730-738.
22. Engström G., Börner G., Lindblad B., Janzon L., Lindgärde F. Incidence of fatal or repaired abdominal aortic aneurysm in relation to inflammation-sensitive plasma proteins. Arterioscler Thromb Vasc Biol. 2004 ; 24 (2). 337-341.
23. Jones KG, Brull DJ, Brown LC, et al. Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysms. Circulation. 2001 ; 103 (18). 2260-2265.
24. Rhode LE, Arroyo LH, Rifai N., et al. Plasma concentrations of interleukin-6 and abdominal aortic diameter among subjects without aortic dialatation. Arterioscler Thromb Vasc Biol. 1999 ; 19 (7). 1695-1699.
25. Shteinberg D., Halak M., Shapiro S., et al. Abdominal aortic aneurysm and aortic occlusive disease: a comparison of risk factors and inflammatory response. Eur J Vasc Endovasc Surg. 2000 ; 20 (5). 462-465.
26. Vainas T., Lubbers T., Stassen FRM, et al. Serum C-reactive protein level is associated with abdominal aortic aneurysm size and may be produced by aneurysmal tissue. Circulation. 2003 ; 107 (8). 1103-1105.
27. Vorp DA, Lee PC, Wang DH, et al. Association of intraluminal thrombus in abdominal aortic aneurysm with local hypoxia and wall weakning. J Vasc Surg. 2001 ; 34 (2). 291-299.
28. Touat Z., Ollivier V., Dai J., et al. Renewal of mural thrombus releases plasma markers and is involved in aortic abdominal aneurysm evolution. Am J Pathol. 2006 ; 168 (3). 1022-1030.
29. Hans SS, Jareunpoon O., Balasubramaniam M., Zelenock GB Size and location of thrombus in intact and ruptured abdominal aortic aneurysms. J Vasc Surg. 2005 ; 41 (4). 584-588.
30. Stenbaek J., Kalin B., Swedenborg J. Growth of thrombus is a better predictor for rupture than diameter in patients with abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2000 ; 20 (5). 466-469.
31. Kazi M., Thyberg J., Religa P., et al. Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall. J Vasc Surg. 2003 ; 38 (6). 1283-1292.
32. Kazi M., Zhu C., Roy J., et al. Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm. Arterioscler Thromb Vasc Biol. 2005 ; 25 (7). 1341-1346.
33. Paraskevas KI, Liapis CD, Hamilton G., Mikhaildis DP Are statins an option in the management of abdominal aortic aneurysms ? Vasc Endovasc Surg. 2008 ; 42 (2). 128-134.
34. Gottsäter A., Flondell-Site D., Kölbel T., Lindblad B. Associations between statin treatment and markers of inflammation, vasoconstriction, and coagulation in patients with abdominal aortic aneurysm. Vasc Endovascular Surg. 2008 / 2009 ; 42 (6). 567-573.