Encephalitis and epilepsy

Seminars in Immunopathology

Volumn 31, Issue 4, 2009, Pages 537-544

  Bauer, Jan ^a   Bien, Christian G ^b  

^a Medical University of Vienna   (Austria)

^b UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Encephalitis; Epilepsy; Inflammation; Paraneoplastic; Seizures

Indexed keywords

ANTIBODY;

CELL DEATH; CENTRAL NERVOUS SYSTEM; CYTOTOXIC T LYMPHOCYTE; ENCEPHALITIS; EPILEPSY; HUMAN; IMMUNE RESPONSE; INFLAMMATION; NERVE CELL NECROSIS; PARANEOPLASTIC NEUROPATHY; PATHOGENICITY; PATHOLOGY; PRIORITY JOURNAL; RASMUSSEN SYNDROME; REVIEW; SEIZURE;

BRAIN; CELL DEATH; ENCEPHALITIS; EPILEPSY; HUMANS; INFLAMMATION; NEURONS; PARANEOPLASTIC SYNDROMES, NERVOUS SYSTEM; T-LYMPHOCYTES;

EID: 73449133339     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-009-0176-1     Document Type: Review

References (75)

1. T Rasmussen J Olszewski D Lloyd-Smith 1958 Focal seizures due to chronic localized encephalitis Neurology 8 435 445 1:STN:280:DyaG1c7gvFCqtQ%3D%3D 13566382
2. CG Bien H Urbach M Deckert J Schramm OD Wiestler H Lassmann CE Elger 2002 Diagnosis and staging of Rasmussen's encephalitis by serial MRI and histopathology Neurology 58 250 257 1:STN:280:DC%2BD38%2FnvV2gsA%3D%3D 11805253
3. CG Bien G Widman H Urbach R Sassen S Kuczaty OD Wiestler J Schramm CE Elger 2002 The natural history of Rasmussen's encephalitis Brain 125 1751 1759 10.1093/brain/awf176 12135966
4. CG Bien T Granata C Antozzi JH Cross O Dulac M Kurthen H Lassmann R Mantegazza JG Villemure R Spreafico CE Elger 2005 Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement Brain 128 454 471 10.1093/brain/awh415 1:STN:280:DC%2BD2M%2FotlOqug%3D%3D 15689357 (Pubitemid 40380182)
5. RB Darnell JB Posner 2003 Paraneoplastic syndromes involving the nervous system N Engl J Med 349 1543 1554 10.1056/NEJMra023009 1:CAS:528: DC%2BD3sXotFGhs78%3D 14561798 (Pubitemid 37255041)
6. RA Henson HL Hoffman H Urich 1965 Encephalomyelitis with carcinoma Brain 88 449 464 10.1093/brain/88.3.449 1:STN:280:DyaF28%2FgvFyntg%3D%3D 5890519
7. JA Corsellis GJ Goldberg AR Norton 1968 "Limbic encephalitis" and its association with carcinoma Brain 91 481 496 10.1093/brain/91.3.481 1:STN:280:DyaF1M%2FltlSgsA%3D%3D 5723018
8. NE Anderson JM Cunningham JB Posner 1987 Autoimmune pathogenesis of paraneoplastic neurological syndromes Crit Rev Neurobiol 3 245 299 1:STN:280:DyaL1c%2Flt12hsw%3D%3D 3315239
9. A Saiz Y Blanco L Sabater F Gonzalez L Bataller R Casamitjana L Ramio-Torrenta F Graus 2008 Spectrum of neurological syndromes associated with glutamic acid decarboxylase antibodies: diagnostic clues for this association Brain 131 Pt 10 2553 2563 10.1093/brain/awn183 18687732
10. J Dalmau AJ Gleichman EG Hughes JE Rossi X Peng M Lai SK Dessain MR Rosenfeld R Balice-Gordon DR Lynch 2008 Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies Lancet Neurol 7 1091 1098 10.1016/S1474-4422(08)70224-2 1:CAS:528:DC%2BD1cXhsFCrsLrF 18851928
11. S Jarius LA Hoffmann O Stich L Clover S Rauer A Vincent R Voltz 2008 Relative frequency of VGKC and 'classical' paraneoplastic antibodies in patients with limbic encephalitis J Neurol 255 1100 1101 10.1007/s00415-008-0845-3 1:STN:280:DC%2BD1crjtVOiuw%3D%3D 18574619
12. Robitaille Y (1991) Neuropathologic aspects of chronic encephalitis. In: Andermann F (ed) Chronic encephalitis and epilepsy. Rasmussen's syndrome. Butterworth-Heinemann, Boston, pp 79-110
13. MA Farrell O Droogan DL Secor V Poukens B Quinn HV Vinters 1995 Chronic encephalitis associated with epilepsy: immunohistochemical and ultrastructural studies Acta Neuropathol Berl 89 313 321 10.1007/BF00309624 1:STN:280: DyaK2MzjsFWgtQ%3D%3D 7610762
14. J Bauer CE Elger VH Hans J Schramm H Urbach H Lassmann CG Bien 2007 Astrocytes are a specific immunological target in Rasmussen's encephalitis Ann Neurol 62 67 80 10.1002/ana.21148 17503512 (Pubitemid 47235282)
15. F Graus T Ribalta E Campo R Monforte A Urbano C Rozman 1990 Immunohistochemical analysis of the immune reaction in the nervous system in paraneoplastic encephalomyelitis Neurology 40 219 222 1:STN:280: DyaK3c7jslaltg%3D%3D 2405292
16. F Bernal F Graus A Pifarre A Saiz B Benyahia T Ribalta 2002 Immunohistochemical analysis of anti-Hu-associated paraneoplastic encephalomyelitis Acta Neuropathol (Berl) 103 509 515 10.1007/s00401-001-0498-0 1:CAS:528:DC%2BD38XisFWmtro%3D (Pubitemid 36075348)
17. EJ Dunstan JB Winer 2006 Autoimmune limbic encephalitis causing fits, rapidly progressive confusion and hyponatraemia Age Ageing 35 536 537 10.1093/ageing/afl045 16763057 (Pubitemid 44295648)
18. DC Park DL Murman KD Perry LA Bruch 2007 An autopsy case of limbic encephalitis with voltage-gated potassium channel antibodies Eur J Neurol 14 e5 e6 10.1111/j.1468-1331.2007.01924.x 1:STN:280:DC%2BD2srmt1ajtA%3D%3D 17880556 (Pubitemid 47459748)
19. J Dalmau E Tüzün HY Wu J Masjuan JE Rossi A Voloschin JM Baehring H Shimazaki R Koide D King W Mason LH Sansing MA Dichter MR Rosenfeld DR Lynch 2007 Paraneoplastic anti-N-methyl-d-aspartate receptor encephalitis associated with ovarian teratoma Ann Neurol 61 25 36 10.1002/ana.21050 1:CAS:528:DC%2BD2sXitlyjt7o%3D 17262855 (Pubitemid 46214241)
20. CG Bien J Bauer TL Deckwerth H Wiendl M Deckert OD Wiestler J Schramm CE Elger H Lassmann 2002 Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis Ann Neurol 51 311 318 10.1002/ana.10100 1:CAS:528:DC%2BD38XitlWqtrc%3D 11891826 (Pubitemid 34206287)
21. FW Gay TJ Drye GW Dick MM Esiri 1997 The application of multifactorial cluster analysis in the staging of plaques in early multiple sclerosis. Identification and characterization of the primary demyelinating lesion Brain 120 1461 1483 10.1093/brain/120.8.1461 9278635 (Pubitemid 27344712)
22. J Booss MM Esiri WW Tourtellotte DY Mason 1983 Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis J Neurol Sci 62 219 232 10.1016/0022-510X(83) 90201-0 1:STN:280:DyaL2c7jslOjtQ%3D%3D 6607973
23. CK Petito JE Torres-Munoz F Zielger M McCarthy 2006 Brain CD8+ and cytotoxic T lymphocytes are associated with, and may be specific for, human immunodeficiency virus type 1 encephalitis in patients with acquired immunodeficiency syndrome J Neurovirol 12 272 283 10.1080/13550280600879204 1:CAS:528:DC%2BD28XhtFWksbnP 16966218 (Pubitemid 44382979)
24. Y Li A Uccelli KD Laxer MC Jeong HV Vinters WW Tourtellotte SL Hauser JR Oksenberg 1997 Local-clonal expansion of infiltrating T lymphocytes in chronic encephalitis of Rasmussen J Immunol 158 1428 1437 1:CAS:528:DyaK2sXitFaju7c%3D 9013988
25. N Schwab CG Bien A Waschbisch A Becker GH Vince K Dornmair H Wiendl 2009 CD8+ T cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery Brain 132 1236 1246 10.1093/brain/awp003 19179379
26. J Dalmau HM Furneaux MK Rosenblum F Graus JB Posner 1991 Detection of the anti-Hu antibody in specific regions of the nervous system and tumor from patients with paraneoplastic encephalomyelitis/sensory neuronopathy Neurology 41 1757 1764 1:STN:280:DyaK38%2FltVahtQ%3D%3D 1944905
27. B Giometto GC Marchiori P Nicolao T Scaravilli A Lion PG Bardin B Tavolato 1997 Sub-acute cerebellar degeneration with anti-Yo autoantibodies: immunohistochemical analysis of the immune reaction in the central nervous system Neuropathol Appl Neurobiol 23 468 474 10.1111/j.1365-2990.1997.tb01323.x 1:CAS:528:DyaK1cXlsl2rtQ%3D%3D 9460712
28. J Dalmau SH Gultekin R Voltz R Hoard T DesChamps C Balmaceda T Batchelor E Gerstner J Eichen J Frennier JB Posner MR Rosenfeld 1999 Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders Brain 122 27 39 10.1093/brain/122.1.27 10050892 (Pubitemid 29046270)
29. WC Jean J Dalmau A Ho JB Posner 1994 Analysis of the IgG subclass distribution and inflammatory infiltrates in patients with anti-Hu-associated paraneoplastic encephalomyelitis Neurology 44 140 147 1:STN:280: DyaK2c7hvFelsA%3D%3D 8290049
30. J Verschuuren L Chuang MK Rosenblum F Lieberman A Pryor JB Posner J Dalmau 1996 Inflammatory infiltrates and complete absence of Purkinje cells in anti-Yo-associated paraneoplastic cerebellar degeneration Acta Neuropathol (Berl) 91 519 525 10.1007/s004010050460 1:CAS:528:DyaK28Xjt1Wluro%3D (Pubitemid 26133664)
31. R Voltz HS Gultekin JB Posner MR Rosenfeld J Dalmau 1998 Sera of patients with testicular cancer and paraneoplastic limbic/brainstem encephalitis harbor an antineuronal antibody (anti-Ta) that recognizes a novel neuronal protein J Neurol 245 6/7 379 Ref type: abstract
32. K Tanaka M Tanaka T Inuzuka R Nakano S Tsuji 1999 Cytotoxic T lymphocyte-mediated cell death in paraneoplastic sensory neuronopathy with anti-Hu antibody J Neurol Sci 163 159 162 10.1016/S0022-510X(99)00029-5 1:CAS:528:DyaK1MXit1Wqs7s%3D 10371077 (Pubitemid 29234239)
33. F Bernal S Shams'ili I Rojas R Sanchez-Valle A Saiz J Dalmau J Honnorat P Sillevis Smitt F Graus 2003 Anti-Tr antibodies as markers of paraneoplastic cerebellar degeneration and Hodgkin's disease Neurology 60 230 234 1:STN:280:DC%2BD3s%2FktlWhtA%3D%3D 12552036 (Pubitemid 36152014)
34. DT Blumenthal KL Salzman KB Digre RL Jensen WA Dunson J Dalmau 2006 Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis Neurology 67 146 149 10.1212/01.wnl.0000223647.83708.20 1:STN:280:DC%2BD28vhtFeqtw%3D%3D 16832096 (Pubitemid 44305481)
35. M Tanaka K Tanaka S Tokiguchi K Shinozawa S Tsuji 1999 Cytotoxic T cells against a peptide of Yo protein in patients with paraneoplastic cerebellar degeneration and anti-Yo antibody J Neurol Sci 168 28 31 10.1016/S0022-510X(99) 00163-X 1:CAS:528:DyaK1MXmt1ektb4%3D 10500270 (Pubitemid 29438683)
36. R Voltz J Dalmau JB Posner MR Rosenfeld 1998 T-cell receptor analysis in anti-Hu associated paraneoplastic encephalomyelitis Neurology 51 1146 1150 1:STN:280:DyaK1cvlt1yjtw%3D%3D 9781545
37. ML Albert LM Austin RB Darnell 2000 Detection and treatment of activated T cells in the cerebrospinal fluid of patients with paraneoplastic cerebellar degeneration Ann Neurol 47 9 17 10.1002/1531-8249(200001)47:1<9::AID- ANA5>3.0.CO;2-I 1:STN:280:DC%2BD3c%2FpsF2mtQ%3D%3D 10632096 (Pubitemid 30033645)
38. F Graus A Saiz M Lai J Bruna F Lopez L Sabater Y Blanco MJ Rey T Ribalta J Dalmau 2008 Neuronal surface antigen antibodies in limbic encephalitis: clinical-immunologic associations Neurology 71 930 936 10.1212/01.wnl. 0000325917.48466.55 1:CAS:528:DC%2BD1cXhtVygurvM 18794496
39. SW Rogers PI Andrews LC Gahring T Whisenand K Cauley B Crain TE Hughes SF Heinemann JO McNamara 1994 Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis Science 265 648 651 10.1126/science.8036512 1:CAS:528:DyaK2cXltVKns70%3D 8036512
40. KD Whitney JM Andrews JO McNamara 1999 Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitis Neurology 53 699 708 1:STN:280:DyaK1MvhslWmtg%3D%3D 10489029
41. M Levite IA Fleidervish A Schwarz D Pelled AH Futerman 1999 Autoantibodies to the glutamate receptor kill neurons via activation of the receptor ion channel J Autoimmun 13 61 72 10.1006/jaut.1999.0301 1:STN:280:DyaK1MzntFOhtA%3D%3D 10441169 (Pubitemid 29367008)
42. PI Andrews MA Dichter SF Berkovic MR Newton JO McNamara 1996 Plasmapheresis in Rasmussen's encephalitis Neurology 46 242 246 1:STN:280:DyaK287ktlWqtQ%3D%3D 8559385
43. T Granata L Fusco G Gobbi E Freri F Ragona G Broggi R Mantegazza L Giordano F Villani G Capovilla F Vigevano BD Bernardina R Spreafico C Antozzi 2003 Experience with immunomodulatory treatments in Rasmussen's encephalitis Neurology 61 1807 1810 1:STN:280:DC%2BD2c%2FisVWjsQ%3D%3D 14694056
44. F Villani R Spreafico L Farina AR Giovagnoli P Bernasconi T Granata G Avanzini 2001 Positive response to immunomodulatory therapy in an adult patient with Rasmussen's encephalitis Neurology 56 248 250 1:STN:280: DC%2BD3M7pt1yhtA%3D%3D 11160964
45. R Watson Y Jiang I Bermudez L Houlihan L Clover K McKnight JH Cross IK Hart A Roubertie J Valmier Y Hart J Palace D Beeson A Vincent B Lang 2004 Absence of antibodies to glutamate receptor type 3 (GluR3) in Rasmussen encephalitis Neurology 63 43 50 1:CAS:528:DC%2BD2cXltVOgurk%3D 15249609
46. E Alvarez-Baron CG Bien J Schramm CE Elger AJ Becker S Schoch 2008 Autoantibodies to Munc18, cerebral plasma cells and B-lymphocytes in Rasmussen encephalitis Epilepsy Res 80 93 97 10.1016/j.eplepsyres.2008.03.007 1:CAS:528:DC%2BD1cXntlSrs7k%3D 18440783
47. R Watson JE Jepson I Bermudez S Alexander Y Hart K McKnight A Roubertie F Fecto J Valmier DB Sattelle D Beeson A Vincent B Lang 2005 Alpha7-acetylcholine receptor antibodies in two patients with Rasmussen encephalitis Neurology 65 1802 1804 10.1212/01.wnl.0000191566.86977.04 1:STN:280:DC%2BD2Mnmt1Gnuw%3D%3D 16344526 (Pubitemid 43754417)
48. M Coesmans PA Smitt DJ Linden R Shigemoto T Hirano Y Yamakawa AM van Alphen C Luo JN van der Geest JM Kros CA Gaillard MA Frens CI de Zeeuw 2003 Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies Ann Neurol 53 325 336 10.1002/ana.10451 1:CAS:528:DC%2BD3sXit1yntLo%3D 12601700 (Pubitemid 36258636)
49. J Dalmau MR Rosenfeld 2008 Paraneoplastic syndromes of the CNS Lancet Neurol 7 327 340 10.1016/S1474-4422(08)70060-7 18339348
50. PA Sillevis Smitt GT Manley JB Posner 1995 Immunization with the paraneoplastic encephalomyelitis antigen HuD does not cause neurologic disease in mice Neurology 45 1873 1878 1:STN:280:DyaK28%2Fit1WltQ%3D%3D 7477985
51. K Tanaka M Tanaka S Igarashi O Onodera T Miyatake S Tsuji 1995 Trial to establish an animal model of paraneoplastic cerebellar degeneration with anti-Yo antibody. 2. Passive transfer of murine mononuclear cells activated with recombinant Yo protein to paraneoplastic cerebellar degeneration lymphocytes in severe combined immunodeficiency mice Clin Neurol Neurosurg 97 101 105 10.1016/0303-8467(95)00006-6 1:STN:280:DyaK2MzgvVyjtw%3D%3D 7788964
52. A Llado P Mannucci AF Carpentier S Paris Y Blanco A Saiz JY Delattre F Graus 2004 Value of Hu antibody determinations in the follow-up of paraneoplastic neurologic syndromes Neurology 63 1947 1949 1:STN:280: DC%2BD2crosFOlug%3D%3D 15557520
53. J Dalmau HS Gultekin JB Posner 1999 Paraneoplastic neurologic syndromes: pathogenesis and physiopathology Brain Pathol 9 275 284 1:STN:280: DyaK1M3jsFWmsw%3D%3D 10219745
54. A Reetz M Solimena M Matteoli F Folli K Takei CP De 1991 GABA and pancreatic beta-cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic-like microvesicles suggests their role in GABA storage and secretion EMBO J 10 1275 1284 1:CAS:528:DyaK3MXktVWms7o%3D 2022191
55. S Christgau HJ Aanstoot H Schierbeck K Begley S Tullin K Hejnaes S Baekkeskov 1992 Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain J Cell Biol 118 309 320 10.1083/jcb.118.2.309 1:CAS:528:DyaK38XkvVOgt7o%3D 1321158
56. MH Barnett JD Parratt ES Cho JW Prineas 2009 Immunoglobulins and complement in postmortem multiple sclerosis tissue Ann Neurol 65 32 46 10.1002/ana.21524 19194879
57. EM Tan FD Shi 2003 Relative paradigms between autoantibodies in lupus and autoantibodies in cancer Clin Exp Immunol 134 169 177 10.1046/j.1365-2249.2003. 02259.x 1:CAS:528:DC%2BD3sXpsFWrtbg%3D 14616773 (Pubitemid 37372266)
58. D Alarcon-Segovia A Ruiz-Arguelles L Llorente 1996 Broken dogma: penetration of autoantibodies into living cells Immunol Today 17 163 164 10.1016/S0167-5699(96)90258-3 1:CAS:528:DyaK28XitFSqu7g%3D 8871346
59. M Abedi-Valugerdi H Hu G Moller 1999 Mercury-induced anti-nucleolar autoantibodies can transgress the membrane of living cells in vivo and in vitro Int Immunol 11 605 615 10.1093/intimm/11.4.605 1:CAS:528:DyaK1MXivVeksbg%3D 10323214
60. P Sillevis Smitt A Kinoshita B De Leeuw W Moll M Coesmans D Jaarsma S Henzen-Logmans C Vecht C De Zeeuw N Sekiyama S Nakanishi R Shigemoto 2000 Paraneoplastic cerebellar ataxia due to autoantibodies against a glutamate receptor N Engl J Med 342 21 27 10.1056/NEJM200001063420104 1:STN:280: DC%2BD3c%2FnsVWitw%3D%3D 10620645 (Pubitemid 30020656)
61. A Vincent C Buckley JM Schott I Baker BK Dewar N Detert L Clover A Parkinson CG Bien S Omer B Lang MN Rossor J Palace 2004 Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis Brain 127 701 712 10.1093/brain/awh077 14960497 (Pubitemid 38295483)
62. M Schimmel CG Bien A Vincent W Schenk J Penzien 2009 Successful treatment of anti-N-methyl-d-aspartate receptor encephalitis presenting with catatonia Arch Dis Child 94 314 316 10.1136/adc.2008.149021 1:STN:280: DC%2BD1M3ivVWnug%3D%3D 19307202
63. M Barnett J Prosser I Sutton GM Halmagyi L Davies C Harper J Dalmau 2001 Paraneoplastic brain stem encephalitis in a woman with anti-Ma2 antibody J Neurol Neurosurg Psychiatry 70 222 225 10.1136/jnnp.70.2.222 1:STN:280:DC%2BD3M7nvFartg%3D%3D 11160472 (Pubitemid 32127861)
64. NA Thornberry TA Rano EP Peterson DM Rasper T Timkey M Garcia-Calvo VM Houtzager PA Nordstrom S Roy JP Vaillancourt KT Chapman DW Nicholson 1997 A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis J Biol Chem 272 17907 17911 10.1074/jbc.272.29.17907 1:CAS:528:DyaK2sXkslKgtbc%3D 9218414 (Pubitemid 27306365)
65. R Liguori A Vincent L Clover P Avoni G Plazzi P Cortelli A Baruzzi T Carey P Gambetti E Lugaresi P Montagna 2001 Morvan's syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels Brain 124 2417 2426 10.1093/brain/124.12.2417 1:STN:280:DC%2BD3MnkvV2qtA%3D%3D 11701596
66. K Ishida H Mitoma Y Wada T Oka J Shibahara Y Saito S Murayama H Mizusawa 2007 Selective loss of Purkinje cells in a patient with anti-glutamic acid decarboxylase antibody-associated cerebellar ataxia J Neurol Neurosurg Psychiatry 78 190 192 10.1136/jnnp.2006.091116 17119008 (Pubitemid 46220221)
67. L Bataller KA Kleopa GF Wu JE Rossi MR Rosenfeld J Dalmau 2007 Autoimmune limbic encephalitis in 39 patients: immunophenotypes and outcomes J Neurol Neurosurg Psychiatry 78 381 385 10.1136/jnnp.2006.100644 1:STN:280: DC%2BD2s7msFWktQ%3D%3D 16980333 (Pubitemid 46580546)
68. A Vezzani M Conti A De Luigi T Ravizza D Moneta F Marchesi MG De Simoni 1999 Interleukin-1beta immunoreactivity and microglia are enhanced in the rat hippocampus by focal kainate application: functional evidence for enhancement of electrographic seizures J Neurosci 19 5054 5065 1:CAS:528:DyaK1MXjvVGjtLo%3D 10366638
69. C Dube A Vezzani M Behrens T Bartfai TZ Baram 2005 Interleukin-1beta contributes to the generation of experimental febrile seizures Ann Neurol 57 152 155 10.1002/ana.20358 1:CAS:528:DC%2BD2MXpsFSrtA%3D%3D 15622539 (Pubitemid 40053330)
70. A Vezzani T Granata 2005 Brain inflammation in epilepsy: experimental and clinical evidence Epilepsia 46 1724 1743 10.1111/j.1528-1167.2005.00298.x 1:CAS:528:DC%2BD2MXhtlelsrzP 16302852 (Pubitemid 44921957)
71. CG Bien CE Elger Y Leitner M Gomori B Ran H Urbach B Wilken I Korn-Lubetzki 2007 Slowly progressive hemiparesis in childhood as a consequence of Rasmussen encephalitis without or with delayed-onset seizures Eur J Neurol 14 387 390 10.1111/j.1468-1331.2007.01684.x 1:STN:280:DC%2BD2s7osl2hsA%3D%3D 17388985 (Pubitemid 46481165)
72. I Korn-Lubetzki CG Bien J Bauer M Gomori H Wiendl L Trajo H Ovadia B Wilken VH Hans CE Elger H Hurvitz I Steiner 2004 Rasmussen encephalitis with active inflammation and delayed seizures onset Neurology 62 984 986 1:STN:280:DC%2BD2c7ksVCjtg%3D%3D 15037707
73. M Hauf R Wiest A Nirkko S Strozzi A Federspiel 2009 Dissociation of epileptic and inflammatory activity in Rasmussen Encephalitis Epilepsy Res 10.1016/j.eplepsyres.2008.11.009 19121924
74. CG Bien U Gleissner R Sassen G Widman H Urbach CE Elger 2004 An open study of tacrolimus therapy in Rasmussen encephalitis Neurology 62 2106 2109 1:CAS:528:DC%2BD2cXktVKgtrY%3D 15184626
75. S Mata GC Muscas I Naldi E Rosati S Paladini B Cruciatti F Bisulli M Paganini G Mazzi S Sorbi P Tinuper 2008 Non-paraneoplastic limbic encephalitis associated with anti-glutamic acid decarboxylase antibodies J Neuroimmunol 199 155 159 10.1016/j.jneuroim.2008.05.015 1:CAS:528:DC%2BD1cXptVWqtro%3D 18586329