Lipodystrophy and anti-retroviral therapy as predictors of sub-clinical atherosclerosis in human immunodeficiency virus infected subjects

Atherosclerosis

Volumn 208, Issue 1, 2010, Pages 222-227

  Guaraldi, Giovanni ^a   Stentarelli, Chiara ^a   Zona, Stefano ^a   Orlando, Gabriella ^a   Carli, Federica ^a   Ligabue, Guido ^b   Lattanzi, Antonella ^b   Zaccherini, Giacomo ^a   Rossi, Rosario ^b   Modena, Maria Grazia ^b   Alexopoulos, Nikolaos ^c   Palella, Frank ^d   Raggi, Paolo ^c  

^a Metabolic Clinic   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Atherosclerosis; Coronary artery calcium; Human immunodeficiency virus

Indexed keywords

ANTILIPEMIC AGENT; ANTIRETROVIRUS AGENT; CALCIUM; HYPERTENSIVE AGENT; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ADULT; AGE DISTRIBUTION; ARTICLE; ATHEROSCLEROSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORONARY ARTERY; CROSS-SECTIONAL STUDY; DIAGNOSTIC IMAGING; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERTENSION; LIPID STORAGE; LIPODYSTROPHY; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCORING SYSTEM; SEX RATIO;

ANTI-RETROVIRAL AGENTS; ATHEROSCLEROSIS; CALCIUM; CORONARY ANGIOGRAPHY; CROSS-SECTIONAL STUDIES; FEMALE; HIV INFECTIONS; HUMANS; LIPODYSTROPHY; MALE; MIDDLE AGED;

EID: 73449110896     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2009.06.011     Document Type: Article

References (36)

1. Palella Jr. F.J., Delaney K.M., Moorman A.C., et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 338 (1998) 853-860
2. Friis-Moller N., Reiss P., Sabin C.A., et al. Class of antiretroviral drugs and the risk of myocardial infarction. N Engl J Med 356 (2007) 1723-1735
3. Sklar P., and Masur H. HIV infection and cardiovascular disease-is there really a link?. N Engl J Med 349 (2003) 2065-2067
4. Anderson J.L. Infection, antibiotics, and atherothrombosis-end of the road or new beginnings?. N Engl J Med 352 (2005) 1706-1709
5. Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., and Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 336 (1997) 973-979
6. Friis-Moller N., Sabin C.A., Weber R., et al. Combination antiretroviral therapy and the risk of myocardial infarction. N Engl J Med 349 (2003) 1993-2003
7. Morse C.G., and Kovacs J.A. Metabolic and skeletal complications of HIV infection: the price of success. JAMA 296 (2006) 844-854
8. Mercie P., Thiebaut R., Lavignolle V., et al. Evaluation of cardiovascular risk factors in HIV-1 infected patients using carotid intima-media thickness measurement. Ann Med 34 (2002) 55-63
9. Hsue P.Y., Lo J.C., Franklin A., et al. Progression of atherosclerosis as assessed by carotid intima-media thickness in patients with HIV infection. Circulation 109 (2004) 1603-1608
10. Mangili A., Gerrior J., Tang A.M., et al. Risk of cardiovascular disease in a cohort of HIV-infected adults: a study using carotid intima-media thickness and coronary artery calcium score. Clin Infect Dis 43 (2006) 1482-1489
11. Currier J.S., Kendall M.A., Henry W.K., et al. Progression of carotid artery intima-media thickening in HIV-infected and uninfected adults. AIDS 21 (2007) 1137-1145
12. Stein J.H., Klein M.A., Bellehumeur J.L., et al. Use of human immunodeficiency virus-1 protease inhibitors is associated with atherogenic lipoprotein changes and endothelial dysfunction. Circulation 104 (2001) 257-262
13. Schillaci G., De Socio G.V., Pucci G., et al. Aortic stiffness in untreated adult patients with human immunodeficiency virus infection. Hypertension 52 (2008) 308-313
14. van Vonderen M.G., Smulders Y.M., Stehouwer C.D., et al. Carotid intima-media thickness and arterial stiffness in HIV-infected patients: the role of HIV, antiretroviral therapy, and lipodystrophy. J Acquir Immune Defic Syndr (2009)
15. Acevedo M., Sprecher D.L., Calabrese L., et al. Pilot study of coronary atherosclerotic risk and plaque burden in HIV patients: 'a call for cardiovascular prevention'. Atherosclerosis 163 (2002) 349-354
16. Meng Q., Lima J.A., Lai H., et al. Coronary artery calcification, atherogenic lipid changes, and increased erythrocyte volume in black injection drug users infected with human immunodeficiency virus-1 treated with protease inhibitors. Am Heart J 144 (2002) 642-648
17. Talwani R., Falusi O.M., Mendes de Leon C.F., et al. Electron beam computed tomography for assessment of coronary artery disease in HIV-infected men receiving antiretroviral therapy. J Acquir Immune Defic Syndr 30 (2002) 191-195
18. Lai S., Lima J.A., Lai H., et al. Human immunodeficiency virus 1 infection, cocaine, and coronary calcification. Arch Intern Med 165 (2005) 690-695
19. Robinson F.P., Hoff J.A., and Kondos G.T. Coronary artery calcium in HIV-infected men treated with highly active antiretroviral therapy. J Cardiovasc Nurs 20 (2005) 149-154
20. Mangili A., Jacobson D.L., Gerrior J., et al. Metabolic syndrome and subclinical atherosclerosis in patients infected with HIV. Clin Infect Dis 44 (2007) 1368-1374
21. Kingsley L.A., Cuervo-Rojas J., Munoz A., et al. Subclinical coronary atherosclerosis, HIV infection and antiretroviral therapy: Multicenter AIDS Cohort Study. AIDS 22 (2008) 1589-1599
22. Sankatsing R.R., de Groot E., Jukema J.W., et al. Surrogate markers for atherosclerotic disease. Curr Opin Lipidol 16 (2005) 434-441
23. Rumberger J.A., Brundage B.H., Rader D.J., and Kondos G. Electron beam computed tomographic coronary calcium scanning: a review and guidelines for use in asymptomatic persons. Mayo Clin Proc 74 (1999) 243-252
24. Schmermund A., Baumgart D., Gorge G., et al. Measuring the effect of risk factors on coronary atherosclerosis: coronary calcium score versus angiographic disease severity. J Am Coll Cardiol 31 (1998) 1267-1273
25. Greenland P., LaBree L., Azen S.P., Doherty T.M., and Detrano R.C. Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals. JAMA 291 (2004) 210-215
26. Guaraldi G., Orlando G., Squillace N., et al. Multidisciplinary approach to the treatment of metabolic and morphologic alterations of HIV-related lipodystrophy. HIV Clin Trials 7 (2006) 97-106
27. Human immunodeficiency virus (HIV) infection codes and new codes for Kaposi's sarcoma. MMWR Recomm Rep 1991;40:1-18.
28. Matthews D.R., Hosker J.P., Rudenski A.S., et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1985) 412-419
29. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001;285:2486-97.
30. Lichtenstein K.A., Ward D.J., Moorman A.C., et al. Clinical assessment of HIV-associated lipodystrophy in an ambulatory population. AIDS 15 (2001) 1389-1398
31. Agatston A.S., Janowitz W.R., Hildner F.J., et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15 (1990) 827-832
32. Casau N.C. Perspective on HIV infection and aging: emerging research on the horizon. Clin Infect Dis 41 (2005) 855-863
33. Pischon T., Boeing H., Hoffmann K., et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med 359 (2008) 2105-2120
34. Joy T., Keogh H.M., Hadigan C., et al. Relation of body composition to body mass index in HIV-infected patients with metabolic abnormalities. J Acquir Immune Defic Syndr 47 (2008) 174-184
35. Lai S., Lai H., Meng Q., et al. Effect of cocaine use on coronary calcium among black adults in Baltimore, Maryland. Am J Cardiol 90 (2002) 326-328
36. Raggi P., Khan A., Arepali C., and Stillman A.E. Coronary artery calcium scoring in the age of CT angiography: what is its role?. Curr Atheroscler Rep 10 (2008) 438-443