Simultaneous SIL-TAL1 RT-PCR detection of all tal(d) deletions and identification of novel tal(d) variants

British Journal of Haematology

Volumn 99, Issue 4, 1997, Pages 901-907

  Delabesse, Eric ^a,b   Bernard, Muriel ^a   Landman Parker, Judith ^c   Davi, Frederic ^d   Leboeuf, Daniel ^b   Varet, Bruno ^a   Valensi, Francoise ^b   Macintyre, Elizabeth A ^a,b  

^a CNRS   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

^c ARMAND TROUSSEAU HOSPITAL   (France)

^d PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Molecular diagnostics; PCR; SIL TAL1; T ALL; tal(d)

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ARTICLE; CANCER SCREENING; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; GENE DELETION; GENETIC ANALYSIS; HUMAN; LEUKEMOGENESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHOOL CHILD; SITE DIRECTED MUTAGENESIS; SOUTHERN BLOTTING; T CELL LEUKEMIA;

EID: 0031456951     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.4833286.x     Document Type: Article

References (26)

1. Aplan, P.D., Johnson, B.E., Russell, E., Chervinsky, D.S. & Kirsch, I.R. (1995) Cloning and characterization of TCTA, a gene located at the site of a t(1;3) translocation. Cancer Research. 55, 1917-1921.
2. Aplan, P.D., Lombardi, D.P., Ginsberg, A.M., Cossman, J., Bertness, V.L. & Kirsch, I. (1990) Disruption of the human SCL locus by 'illegitimate' V-(D)-J recombinase activity. Science, 250, 1426-1429.
3. Aplan, P.D., Lombardi, D.P., Reeman, G.H., Sather, H.N., Hammond, G.D. & Kirsch, I. (1992a) Involvement of the putative hematopoietic transcription factor SCL in T-cell acute lymphoblastic leukemia. Blood, 79, 1327-1333.
4. Aplan, P.D., Raimondi, S.C. & Kirsch, I.R. (1992b) Disruption of the SCL gene by a t(1;3) translocation in a patient with T-cell acute lymphoblastic leukemia. Journal of Experimental Medicine, 176, 1305-1310.
5. Baer, R. (1993) TAL1, TAL2 and LYL1: a family of basic helix-loophelix proteins implicated in T-cell acute leukaemia. Seminars in Cancer Biology, 4, 341-347.
6. Bash, R.O., Crist, W.M., Shuster, J.J., Link, M.P., Amylon, M., Pullen, J., Carroll, A.J., Buchanan, G.R., Smith, R.G. & Baer, R. (1993) Clinical features and outcome of T-cell acute lymphoblastic leukemia in childhood with respect to alterations at the TAL1 locus: a Pediatric Oncology Group study. Blood, 81, 2110-2117.
7. Bash, R.O., Hall, S., Timmons, C.F., Crist, W.M., Amylon, M., Smith, R.G. & Baer, R. (1995) Does activation of the TAL1 gene occur in a majority of patients with T-cell acute lymphoblastic leukemia? A Pediatric Oncology Group Study. Blood, 86, 666-676.
8. Begley, C.G., Aplan, P.A., Davey, M.P., Nakahara, K., Tchorz, K., Kurtzberg, J., Hershfield, M.S., Haynes, B.F., Cohen, D.I., Waldmann, T.A. & Kirsch, I. (1989) Chromosomal translocation in a human leukemic stem-cell line disrupts the T cell antigen receptor δ-chain diversity region and results in a previously unreported fusion transcript. Proceedings of the National Academy of Sciences of the United States of America, 86, 2031-2035.
9. Bernard, O., Guglielmi, P., Jonveaux, P., Cherif, D., Gisselbrecht, S., Mauchauffé, M., Berger, R., Larsen, C.-J. & Mathieu-Mahul, D. (1990) Two distinct mechanisms for the SCL gene activation in the t(1;14) translocations of T cell leukemias. Genes, Chromosomes and Cancer, 1, 194-208.
10. Bernard, O., Lecointe, N., Jonveaux, P., Souyri, M., Mauchauffé, M., Berger, R., Larsen, C.-J. & Mathieu-Mahul, D. (1991) Two site-specific deletions and t(1;14) translocation restricted to human T-cell acute leukemias disrupt the 5′ part of the TAL1 gene. Oncogene, 6, 1477-1488.
11. Breit, T.M., Beishuizen, A., Ludwig, W.D., Mol, E.J., Adriaansen, H.J., Vanwering, E.R. & van Dongen, J.J.M. (1993a) TAL1 deletions in T-cell acute lymphoblastic leukemia as PCR target for detection of minimal residual disease. Leukemia. 7, 2004-2011.
12. Breit, T.M., Mol, E.J., Wolverstettero, I.L.M., Ludwig, W.D., Vanwering, E.R. & van Dongen, J.J.M. (1993b) Site-specific deletions involving the TAL1 and SIL genes are restricted to cells of the T-cell receptor alpha/beta lineage: T-cell receptor-delta gene deletion mechanism affects multiple genes. Journal of Experimental Medicine, 177, 965-977.
13. Brown, L., Cheng, J.-T., Chen, Q., Siciliano, M., Crist, W., Buchanan, G. & Baer, R. (1990) Site specific recombination of the TAL1 gene is a common occurrence in human T cell leukemia. EMBO Journal, 9, 3343-3351.
14. Chen, Q., Cheng, J.-Y., Tsai, L.-H., Schneider, N., Buchanan, G., Carroll, A., Crist, W., Ozanne, B., Siciliano, M. & Baer, R. (1990) The TAL gene undergoes chromosome translocation in a T cell leukemia and potentially encodes a helix-loop-helix protein. EMBO Journal, 9, 415-424.
15. Fitzgerald, T.J., Neale, G.A.M., Raimondi, S.C. & Goorha, R.M. (1991) c-TAL, a helix-loop-helix, is juxtaposed to the T-cell receptor β chain gene by a reciprocal translocation t(1;7)(p32;q35). Blood, 78, 2686-2695.
16. Huang, W., Kuang, S.Q., Huang, Q.H., Dong, S., Zhang, T., Gu, L.J., Ching, L.M., Chen, S.J., Chang, L.C. & Chen, Z. (1995) RT/PCR detection of SIL-TAL1 fusion mRNA in Chinese T-cell acute lymphoblastic leukemia (T-ALL). Cancer Genetics and Cytogenetics, 81, 76-82.
17. Jonsson, A.G., Kitchens, R.L., Baer, R.J., Buchanan, G.R. & Smith, R.G. (1991) Rearrangements of the TAL1 locus as clonal markers for T-cell acute lymphoblastic leukemia. Journal of Clinical Investigation, 87, 2029-2035.
18. Kallianpur, A.R., Jordan, J.E. & Brandt, S.J. (1994) The SCL/Tal-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood, 83, 1200-1208.
19. Macintyre, E.A., Smit, L., Ritz, J., Kirsch, I.R. & Strominger, J.L. (1992) Disruption of the SCL locus in T-lymphoid malignancies correlates with Commitment to the T-cell receptor-αβ lineage. Blood, 80, 1511-1520.
20. Mouthon, M.A., Bernard, O., Mitjavila, M.T., Romeo, P.H., Vainchenker, W. & Mathieu-Mahul, D. (1993) Expression of TAL1 and GATA-binding proteins during human hematopoiesis. Blood, 81, 647-655.
21. Nichols, J. & Nimer, S.D. (1992) Transcription factors, translocations, and leukemia. Blood, 80, 2953-2963.
22. Poirel, H., Rack, K., Delabesse, E., Radford-Weiss, I., Troussard, X., Debert, C., Leboeuf, D., Bastard, C., Picard, F., Veil-Buzyn, A., Flandrin, G., Bernard, O. & Macintyre, E. (1996) Incidence and characterziation of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5. Blood, 87, 2496-2505.
23. Poirel, H., Radford-Weiss, I., Rack, K., Troussard, X., Veil, A., Valensi, F., Picard, F., Guesnu, M., Leboeuf, D., Melle, J., Dreyfus, F., Flandrin, G. & Macintyre, E. (1995) Detection of the chromosome 16 CBF beta-MYH11 fusion transcript in myelomonocytic leukemias. Blood, 85, 1313-1322.
24. Romana, S.P., Mauchauffe, M., Le, C.M., Chumakov, I., Le, P.D., Berger, R. & Bernard, O.A. (1995) The t(12;21) of acute lymphoblastic leukemia results in a TEL-AML1 gene fusion. Blood, 85, 3662-3670.
25. Stock, W., Westbrook, C.A., Sher, D.A., Dodge, R., Sobol, R.E., Wurster-Hill, D., Davey, F.R., Larson, R.A., Le Beau, M.M., Aplan, P.D., Frankel, S.R., Stewart, C.C. & Bloomfield, C.D. (1995) Low incidence of TAL1 gene rearrangements in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B study (8762). Clinical Cancer Research, 1, 459-465.
26. Visvader, J. & Begley, C.G. (1991) Helix-loop-helix genes translocated in lymphoid leukemia. Trends in Biochemical Sciences, 16, 330-333.