Value of the identification of microsatellite instability in colorectal cancer

Clinical and Translational Oncology

Volumn 11, Issue 7, 2009, Pages 465-469

  Shaw, Antonio Barrasa ^a   López Guerrero, José Antonio ^a   Fons, Ana Calatrava ^a   García Casado, Zaida ^a   Olavarrieta, Vicente Alapont ^a   Mánez, Jorge Campos ^a   Albaladejo, Carlos Vázquez ^a  

^a INSTITUTO VALENCIANO DE ONCOLOGÍA   (Spain)

Author keywords

Colorectal cancer; Fluoropyrimidines; Microsatellite instability; Prognosis

Indexed keywords

MICROSATELLITE DNA; TUMOR MARKER;

AGED; ARTICLE; COLORECTAL TUMOR; DISEASE FREE SURVIVAL; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MICROSATELLITE INSTABILITY; MIDDLE AGED; PATHOLOGY; PROGNOSIS;

AGED; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE REPEATS; MIDDLE AGED; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 73349134664     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-009-0386-y     Document Type: Article

References (35)

1. Rodriguez-Bigas MA, Boland CR, Hamilton SR et al (1998) A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting highlights and Bethesda guidelines. J Natl Cancer Inst 89:1758-1762. Comment in: J Natl Cancer Inst 1998;90:939-940
2. Perucho M (1996) Cancer of the microsatellite mutator phenotype. Biol Chem 377:675-684
3. Sinicrope FA, Rego RL, Foster N et al (2006) Microsatellite instability accounts for tumour site-related differences in clinicopathologic variables and prognosis in human colon cancers. Am J Gastroenterol 101:2818-2825
4. Jo WS, Carethers JM (2006) Chemotherapeutic implications in microsatellite unstable colorectal cancer. Cancer Biomark 2:51-60
5. Casado E, De Castro J, Belda-Iniesta C et al (2007) Molecular markers in colorectal cancer: Genetic bases for a customised treatment. Clin Transl Oncol 9:549-554
6. Umetani N, Sasaki S, Watanabe T et al (2000) Diagnostic primer sets for microsatellite instability optimized for a minimal amount of damaged DNA from colorectal tissue samples. Ann Surg Oncol 7:276-280
7. Marsoni S (2001) International Multicenter Pooled Analysis of Colon Cancer Trials Investigators. Efficacy of adjuvant fluorouracil and leucovorin in stage B2 and C colon cancer. International Multicenter Pooled Analysis of Colon Cancer Trials Investigators. Semin Oncol 28[1 Suppl 1]:14-19
8. Wolmark N, Colangelo L, Wieand S (2001) National Surgical Adjuvant Breast and Bowel Project trials in colon cancer. Semin Oncol 28[1 Suppl 1]:9-13
9. Aranda E, Abad A, Carrato A et al TTD Group (2006) Guides for adjuvant treatment of colon cancer. TTD Group (Spanish Cooperative Group for Gastrointestinal Tumour Therapy). Clin Transl Oncol 8:98-102
10. Chang SC, Lin JK, Yang SH et al (2006) Relationship between genetic alterations and prognosis in sporadic colorectal cancer. Int J Cancer 118:1721-1727
11. Lim SB, Jeong SY, Lee MR et al (2004) Prognostic significance of microsatellite instability in sporadic colorectal cancer. Int J Colorectal Dis 19:533-537
12. Ward RL, Cheong K, Ku SL et al (2003) Adverse prognostic effect of methylation in colorectal cancer is reversed by microsatellite instability. J Clin Oncol 21:3729-3736
13. Bubb VJ, Curtis LJ, Cunningham C et al (1996) Microsatellite instability and the role of hMSH2 in sporadic colorectalcancer. Oncogene 12:2641-2649
14. Chen WS, Chen JY, Liu JM et al (1997) Microsatellite instability in sporadic-colon-cancer patients with and without liver metastases. Int J Cancer 74:470-474
15. Halling KC, French AJ, McDonnell SK et al (1999) Microsatellite instability and 8p allelic imbalance in stage B2 and C colorectal cancers. J Natl Cancer Inst 91:1295-1303
16. Sinicrope FA, Rego RL, Halling KC et al (2006) Prognostic impact of microsatellite instability and DNA ploidy in human colon carcinoma patients. Gastroenterology 131:729-737
17. Lanza G, Gafà R, Santini A et al (2006) Immunohistochemical test for MLH1 and MSH2 expression predicts clinical outcome in stage II and III colorectal cancer patients. J Clin Oncol 24:2359-2367
18. Westra JL, Plukker JT, Buys CH, Hofstra RM (2004) Genetic alterations in locally advanced stage II/III colon cancer: A search for prognostic markers. Clin Colorectal Cancer 4:252-259
19. Benatti P, Gafà R, Barana D et al (2005) Microsatellite instability and colorectal cancer prognosis. Clin Cancer Res 11:8332-8340. Erratum in: Clin Cancer Res 2006;12:3868-3869
20. Carethers JM, Smith EJ, Behling CA et al (2004) Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer. Gastroenterology 126:394-401
21. Jover R, Zapater P, Castells A et al Gastrointestinal Oncology Group of the Spanish Gastroenterological Association (2006) Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer. Gut 55:848-855
22. Ricciardiello L, Ceccarelli C, Angiolini G et al (2005) High thymidylate synthase expression in colorectal cancer with microsatellite instability: Implications for chemotherapeutic strategies. Clin Cancer Res 11:4234-4240
23. Lamberti C, Lundin S, Bogdanow M et al (2007) Microsatellite instability did not predict individual survival of unselected patients with colorectal cancer. Int J Colorectal Dis 22:145-152
24. Wang C, van Rijnsoever M, Grieu F et al (2003) Prognostic significance of microsatellite instability and Ki-ras mutation type in stage II colorectal cancer. Oncology 64:259-265
25. Westra JL, Schaapveld M, Hollema H et al (2005) Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients. J Clin Oncol 23:5635-5643
26. Malesci A, Laghi L, Bianchi P et al (2007) Reduced likelihood of metastases in patients with microsatellite-unstable colorectal cancer. Clin Cancer Res 13:3831-3839
27. Hemminki A, Mecklin JP, Järvinen H et al (2000) Microsatellite instability is a favorable prognostic indicator in patients with colorectal cancer receiving chemotherapy. Gastroenterology 119:921-928
28. Elsaleh H, Powell B, McCaul K et al (2001) P53 alteration and microsatellite instability have predictive value for survival benefit from chemotherapy in stage III colorectal carcinoma. Clin Cancer Res 7:1343-1349
29. Watanabe T, Wu TT, Catalano PJ et al (2001) Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 344:1196-1206
30. Ribic CM, Sargent DJ, Moore MJ et al (2003) Tumour microsatellite- instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 349:247-257
31. Barratt PL, Seymour MT, Stenning SP et al; UKCCCR AXIS trial collaborators (2002) Adjuvant X-ray and Fluorouracil Infusion Study. DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: A molecular study. Lancet 360:1381-1391
32. Storojeva I, Boulay JL, Heinimann K et al (2005) Prognostic and predictive relevance of microsatellite instability in colorectal cancer. Oncol Rep 14:241-249
33. Kim GP, Colangelo LH, Wieand HS et al National Cancer Institute (2007) Prognostic and predictive roles of high-degree microsatellite instability in colon cancer: A National Cancer Institute-National Surgical Adjuvant Breast and Bowel Project Collaborative Study. J Clin Oncol 25:767-772
34. Popat S, Hubner R, Houlston RS (2005) Systematic review of microsatellite instability and colorectal cancer prognosis. J Clin Oncol 23:609-618
35. des Guetz G, Mariani P, Cucherousset J et al (2007) Microsatellite instability and sensitivitiy to FOLFOX treatment in metastatic colorectal cancer. Anticancer Res 27:2715-2719