Role of serotonin in thromboxane A2-induced coronary chemoreflex

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 3 53-3, 2003, Pages

  Wacker, M J ^a   Wilhelm, H L ^a   Gomez, S E ^a   Floor, E ^a   Orr, J A ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Anesthetized rabbit; Pheylbiguanide; Tropisetron; U 46619; Vagal afferent units

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; SEROTONIN; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR STIMULATING AGENT; TROPISETRON;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; HEART RATE; MALE; MEASUREMENT; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RABBIT; RECEPTOR UPREGULATION; SEROTONIN BLOOD LEVEL; SEROTONIN RELEASE; VAGUS NERVE;

EID: 0037370754     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00617.2002     Document Type: Article

References (47)

1. Azami J, Fozard JR, Round AA, and Wallis DI. The depolarizing action of 5-hydroxytryptamine on rabbit vagal primary afferent and sympathetic neurons and its selective blockade by MDL 72222. Naunyn Schmiedebergs Arch Pharmacol 328: 423-429, 1985.
2. q. Biochem J 291: 235-240, 1993.
3. Bell LB, O'Hagan KP, and Clifford PS. Cardiac but not pulmonary receptors mediate depressor response to IV phenyl biguanide in conscious rabbits. Am J Physiol Regul Integr Comp Physiol 264: R1050-R1057, 1993.
4. Bley KR, Eglen RM, and Wong EHF. Characterization of 5-hydroxytryptamine-induced depolarizations in rat isolated vagus nerve. Eur J Pharmacol 260: 139-147, 1994.
5. 2 mimetic. Am J Physiol Heart Circ Physiol 266: H2320-H2326, 1994.
6. 4 receptor mediating depolarization of the rat isolated vagus nerve. Naunyn Schmiedebergs Arch Pharmacol 352: 74-78, 1995.
7. 2 on some isolated smooth muscle preparations. Br J Pharmacol 73: 773-778, 1981.
8. Coleridge JCG and Coleridge HM. Chemoreflex regulation of the heart. In: Handbook of Physiology. The Cardiovascular System. The Heart. Bethesda, MD: Am Physiol Soc, 1979, sect. 2, vol. I, chapt. 18, p. 653-676.
9. Coleridge JCG, Coleridge HM, and Kidd C. Cardiac receptors in the dog, with particular reference to two types of afferent endings in the ventricular wall. J Physiol 174: 323-339, 1964.
10. 3 receptors. Pharmacol Toxicol 79: 32-39, 1996.
11. Elliot P, Seemungal BM, and Wallis DI. Antagonism of the effects of 5-hydroxytryptamine on the rabbit isolated vagus nerve by BRL 43694 and metoclopramide. Naunyn Schmiedebergs Arch Pharmacol 341: 503-509, 1990.
12. 3 receptors in the heart and lungs of unanesthetized rabbits. Clin Exp Pharmacol Physiol 17: 665-679, 1990.
13. Fozard JR. MDL 72222: a potent and highly selective antagonist at neuronal 5-hydroxytryptamine receptors. Naunyn Schmiedebergs Arch Pharmacol 326: 36-44, 1984.
14. 3 receptor antagonists and anti-emetic mechanisms of action. Anticancer Drugs 3: 79-85, 1992.
15. Fu LW and Longhurst JC. Reflex pressor response to arterial phenylbiguanide: role of abdominal sympathetic visceral afferents. Am J Physiol Heart Circ Physiol 275: H2025-H2035, 1998.
16. Fu LW and Longhurst JC. Role of 5-HT3 receptors in activation of abdominal sympathetic C fibre afferents during ischemia in cats. J Physiol 509: 729-740, 1998.
17. Fu LW and Longhurst JC. Role of activated platelets in excitation of cardiac afferents during myocardial ischemia in cats. Am J Physiol Heart Circ Physiol 282: H100-H109, 2002.
18. 2 stimulates ischemically sensitive cardiac afferents (Abstract). FASEB J 16: A830, 2002.
19. Hainsworth R. Reflexes from the heart. Physiol Rev 71: 617-658, 1991.
20. Hamberg M, Svensson J, and Samuelsson B. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci USA 72: 2994-2998, 1975.
21. Higashi H and Nishi S. 5-Hydroxytryptamine receptors of visceral primary afferent neurons on rabbit nodose ganglia. J Physiol 323: 543-567, 1982.
22. Hintze TH. Reflex regulation of the circulation after stimulation of cardiac receptors by prostaglandins. Fed Proc 46: 73-80, 1987.
23. 2 receptor isoforms in human platelets. J Clin Invest 97: 949-956, 1996.
24. Hirsh PD, Hillis LD, Campbell WB, Firth BG, and Willerson JT. Release of prostaglandins and thromboxanes into the coronary circulation in patients with ischemic heart disease. N Engl J Med 304: 685-691, 1981.
25. 3H]ICS 205-930 labels 5-HT3 recognition sites in membranes of cat and rabbit vagus nerve and superior cervical ganglion. Naunyn Schmiedebergs Arch Pharmacol 340: 396-402, 1989.
26. Ireland SJ and Tyers MB. Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br J Pharmacol 90: 229-238, 1987.
27. Kaufman MP, Baker DG, Coleridge HM, and Coleridge JCG. Stimulation by bradykinin of afferent vagal c-fibers with chemosensitive endings in the heart and aorta of the dog. Circ Res 46: 476-484, 1980.
28. LeBreton GC, Venton DL, Enke SE, and Halushka PV. 13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor. Proc Natl Acad Sci USA 76: 4097-4101, 1979.
29. Leone M, Silvestrini B, Palmery M, and Cheng CY. Identification of multiple biological factors in rabbit serum that modulate dopamine-mediated aortic constriction. Biochem Int 6: 1079-1090, 1992.
30. Longhurst JC, Tjen-ALooi SC, and Fu LW. Cardiac sympathetic afferent activation provoked by myocardial ischemia and reperfusion. Ann NY Acad Sci 940: 74-95, 2001.
31. 3H]iloprost. Neuroscience 65: 493-503, 1995.
32. Mayer GS and Shoup RE. Simultaneous multiple electrode liquid chromatographic-electrochemical assay for catecholamines, indoleamines, and metabolites in brain tissue. J Chromatogr 255: 533-544, 1983.
33. Meller ST, Lewis SJ, Brody MJ, and Gebhart GF. Vagal afferent-mediated inhibition of a nociceptive reflex by iv serotonin in the rat II Role of 5-HT receptor subtypes. Brain Res 585: 71-86, 1992.
34. 2, and prostacyclin. Pharmacol Rev 30: 293-331, 1975.
35. Montalescot G, Drobinski G, Maclouf J, maillet F, Salloum J, Ankri A, Kazatchkine M, Eugene L, Thomas D, and Grosgoeat Y. Evaluation of thromboxane production and complement activation during myocardial ischemia in patients with angina pectoris. Circulation 84: 2054-2062, 1991.
36. Orr JA, Ernst M, Carrithers J, and Shirer HW. Cardiopulmonary responses to HCl infusion are mediated by thromboxane A2 but not by serotonin. Respir Physiol 80: 203-218, 1990.
37. Paasonen MK. Release of 5-hydroxytryptamine from blood platelets. J Pharm Pharmacol 17: 681-697, 1956.
38. 3 receptors of rabbit nodose ganglion neurons in culture. Br J Pharmacol 110: 665-676, 1993.
39. 4 receptor. Naunyn Schmiedebergs Arch Pharmacol 346: 496-503, 1992.
40. Rizzi CA, Coccini T, Onori L, Manzo L, Tonini M. Benzimidazolone derivatives: a new class of 5-hydroxytryptamine4 receptor agonists with prokinetic and acetylcholine releasing properties in the guinea pig ileum. J Pharmacol Exp Ther 261: 412-419, 1992.
41. Sun S, Wang W, and Schultz HD. Activation of cardiac afferents by arachidonic acid: relative contributions of metabolic pathways. Am J Physiol Heart Circ Physiol 281: H93-H104, 2001.
42. 2 analogues in human platelets. J Biol Chem 265: 6836-6844, 1989.
43. 2 receptor mRNA expression in rat sensory ganglia neurons (Abstract). FASEB J 16: A832, 2002.
44. Ustinova EE and Schultz HD. Activation of cardiac vagal afferents in ischemia and reperfusion; prostaglandins versus oxygen-derived free radicals. Circ Res 74: 904-911, 1994.
45. 2 mimetic evokes a bradycardia mediated by stimulation of cardiac vagal afferent nerves. Am J Physiol Heart Circ Physiol 282: H482-H490, 2002.
46. 3 receptor-mediated cardiovascular responses in the conscious rabbit: evidence for 5-HT release from platelets. J Cardiovasc Pharmacol 13: 557-564, 1989.
47. Yoshioka M, Ikeda T, Abe M, Togashi H, Minami M, and Saito H. Pharmacological characterization of 5-hydroxytryptamine-induced excitation of afferent cervical vagus nerve in anaesthetized rats. Br J Pharmacol 106: 544-549, 1992.