Demethylbellidifolin prevents nitroglycerin tolerance via improved aldehyde dehydrogenase 2 activity

Planta Medica

Volumn 75, Issue 14, 2009, Pages 1476-1481

  Shi, Rui Zheng ^a   Li, Xiao Hui ^b   Jia, Su Jie ^b   Fu, Qiong Mei ^a   Chen, Yue Rong ^b   Chen, Jia ^a   Chen, An ^a   Li, Shi Xun ^a   Tan, Gui San ^b   Li, Yuan Jian ^b   Zhang, Guo Gang ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Aldehyde dehydrogenase 2; Demethylbellidifolin; Nitroglycerin tolerance; Reactive oxygen species

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2; ALPHA TOCOPHEROL; CYCLIC GMP; GLYCERYL TRINITRATE; NORBELLIDIFOLIN; PHENYLEPHRINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG INHIBITION; DRUG MECHANISM; DRUG TOLERANCE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; MALE; MEDICINAL PLANT; NONHUMAN; PRESSOR RESPONSE; RAT; SWERTIA; UMBILICAL VEIN; VASCULAR RING; VASODILATATION;

ALDEHYDE DEHYDROGENASE; ANIMALS; ANTIOXIDANTS; AORTA; CYCLIC GMP; DRUG TOLERANCE; ENDOTHELIAL CELLS; HERB-DRUG INTERACTIONS; HUMANS; MALE; MITOCHONDRIAL PROTEINS; NITROGLYCERIN; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SWERTIA; UMBILICAL VEINS; VASODILATOR AGENTS; XANTHENES;

RATTUS; SWERTIA;

EID: 73349127751     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1185774     Document Type: Article

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