Mother-fetus transference of lead and Cadmium in rats: Involvement of metallothionein

Histology and Histopathology

Volumn 24, Issue 12, 2009, Pages 1523-1530

  Benitez, M A ^a   Mendez Armenta, M ^b   Montes, S ^b   Rembao, D ^b   Sanin, L H ^c   Rios, C ^b  

^a Research Center for Food and Development   (Mexico)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c UNIVERSIDAD AUTÓNOMA DE CHIHUAHUA   (Mexico)

Author keywords

Cadmium; Fetus; Lead; Metallothionein; Placenta; Transference

Indexed keywords

RATTUS;

CADMIUM; LEAD; METALLOTHIONEIN;

ANIMAL; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BIRTH WEIGHT; BLOOD; BRAIN; CALIBRATION; CATTLE; DOSE RESPONSE; DRUG EFFECT; FEMALE; FETOMATERNAL TRANSFUSION; FETUS; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; ORAL DRUG ADMINISTRATION; PLACENTA; PREGNANCY; QUALITY CONTROL; RAT; STANDARD;

ADMINISTRATION, ORAL; ANIMALS; BIRTH WEIGHT; BLOOD; BRAIN; CADMIUM; CALIBRATION; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FETUS; IMMUNOHISTOCHEMISTRY; LEAD; MATERNAL-FETAL EXCHANGE; METALLOTHIONEIN; PLACENTA; PREGNANCY; QUALITY CONTROL; RATS; REFERENCE STANDARDS; SPECTROPHOTOMETRY, ATOMIC;

EID: 73349123485     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Ali M.M., Murthy R.C. and Chandra S.V. (1986). Developmental and long-term neurobehavioural toxicity of low level in-utero cadmium exposure in rats. Neurobehav. Toxicol. Teratol. 8, 463-468.
2. Antonio M.T., Corredor L. and Leret M.L. (2003). Study of the activity of several brain enzyme like markers of the neurotoxicity induced by perinatal exposure to lead and/or cadmium. Toxicol. Lett. 143, 331-340.
3. Brako E.E., Wilson A.K., Johan M.M., Blum C.A., Cerny E.A., Williams K.L. and Bhattacharyya M.H. (2003). Cadmium pathways during gestation and lactation in control versus Metallothionein 1,2-knockout mice. Toxicol. Sci. 71, 154-163.
4. Butler-Walker J.B., Houseman J., Seddon L., McMullen E., Tofflemire K., Mills C., Corriveau A., Weber J.P., LeBlanc A., Walker M., Donaldson S.G. and Oostdam J.V. (2006). Maternal and umbilical cord blood levels of mercury, lead, cadmium, and essential trace elements in Arctic Canada. Environ. Res. 100, 295-318.
5. Carrington C.D., Sheehan D.M. and Bolger P.M. (1993). Hazard assessment of lead. Food Addit. Contam. 10, 325-335.
6. Conrad C.C., Walter C.A., Richardson A., Hanes M.A. and Grabowski D.T. (1997). Cadmium toxicity and distribution in metallothionein-I and-II deficient transgenic mice. J. Toxicol. Environ. Health. 52, 527-543.
7. Evans T.J., James-Kracke M.R., Kleiboeker S.B. and Casteel S.W. (2003). Lead enters Rcho-1 trophoblastic cells by calcium transport mechanisms and complexes with cytosolic calcium-binding proteins. Toxicol. Appl. Pharmacol. 186, 77-89.
8. Fuentes M., Torregrosa A., Mora R., Gotzens V., Corbella J. and Domingo J.L. (1996). Placental effects of lead in mice. Placenta 17, 371-376.
9. Galicia-Garcia V., Rojas-Lopez M., Rojas R., Olaiz G. and Rios C. (1997). Cadmium levels in maternal, cord and newborn in Mexico City. Toxicol. Lett. 91, 57-61.
10. Goyer R.A. (1990). Transplacental transport of lead. Environ. Health Perspect. 89,101-105.
11. Goyer R.A. and Cherian M.G. (1992). Role of metallothionein in human placenta and rats exposed to cadmium. IARC Sci. Publ. 118, 239-247.
12. Goyer R.A., Haust M.D. and Cherian M.G. (1992). Cellular localization of Metallothionein in human term placenta. Placenta 13, 349-355.
13. Goyer R.A. (1993). Lead toxicity: current concerns. Environ. Health Perspect. 100, 177-187.
14. Gude M.N., Roberts T.C., Kalionis B. and King G.R. (2004). Growth and function of the normal human placenta. Thromb. Res. 114, 397-407.
15. Henson M.C. and Chedrese P.J. (2004). Endocrine disruption by cadmium, a common environmental toxicant with paradoxical effects on reproduction. Exp. Biol. Med. 229, 383-392.
16. Ishitobi H. and Watanabe C. (2005). Effects of low-dose perinatal cadmium exposure on tissue zinc and copper concentrations in neonatal mice and on the reproductive development of female offspring. Toxicol. Lett. 159, 38-46.
17. Itoh N., Fujita Y., Nakanishi H., Kawai Y., Mayumi T., Hwang G.S., Min K., Onosaka S., Muto N. and Tanaka K. (1996). Binding of Cd to metallothionein in the placenta of Cd-treated mouse. J. Toxicol. Sci. 21, 19-27.
18. Iyengar G.V. and Rapp A. (2001). Human placenta as a 'dual' biomarker for monitoring fetal and maternal environment with special reference to potentially toxic trace elements. Part 3: toxic trace elements in placenta and placenta as a biomarker for these elements. Sci. Total Environ. 280, 221-238.
19. Jauniaux E. and Burton G.J. (2007). Morphological and biological effects of maternal exposure to tobacco smoke on the feto-placental unit. Early Hum Dev. 83, 699-706.
20. Kawai M., Swan K.F., Green A.E., Edwards D.E., Anderson M.B. and Henson M.C. (2002). Placental endocrine disruption induced by cadmium effects on P450 cholesterol side-chain cleavage and 3'-Hydroxysteroid dehydrogenase enzymes in cultured human trophoblasts. Biol. Reprod. 67, 178-183.
21. Kuriwaki J., Nishijo M., Honda R., Tawara K., Nakagawa H., Hori E. and Nishijo H. (2005). Effects of cadmium exposure during pregnancy on trace elements in fetal rat liver and kidney. Toxicol. Lett. 156, 369-376.
22. Lafond J., Hamel A., Tasker L., Vaillancourt C. and Mergler D. (2004). Low environmental contamination by lead in pregnant women: effect on calcium transfer in human placental syncytiotrophoblasts. J. Toxicol. Environ. Health A 67, 1069-1079.
23. Lau J.C., Joseph M.G. and Cherian M.G. (1998). Role of placental metallothionein in maternal to fetal transfer of cadmium in genetically altered mice. Toxicology 127, 167-178.
24. Levin A.A., Kilpper R.W. and Miller R.K. (1987). Fetal toxicity of cadmium chloride. The pharmacokinetics in the pregnant wistar rat. Teratology 36, 163-170.
25. Little B.B., Snell L.M., Johnston W.L., Knoll R.A. and Buschang P.H. (1990). Blood lead levels and growth status in children. Am. J. Hum. Biol. 2, 265-269.
26. Nampoothiri P.L. and Gupta S. (2008). Biochemical effects of gestational coexposure to lead and cadmium on reproductive performance, placenta, and ovary. J. Biochem. Mol. Toxicol. 22, 337-344.
27. Nordberg M. and Nordberg G.F. (2000). Toxicological aspects of metallothionein. Cell. Mol. Biol. (Noisy-le-grand) 46, 451-463.
28. Osman K., Akesson A., Berglund M., Bremme K., Schütz A., Ask K. and Vahter M. (2000). Toxic and essential elements in placentas of Swedish women. Clin. Biochem. 33, 131-138.
29. Peereboom-Stegeman J.H., Van der Velde W.J. and Dessing J.W. (1983). Influence of cadmium on placental structure. Ecotoxicol. Environ. Saf. 7, 79-86.
30. Petersson-Grawe K. and Oskarsson A. (2000). Cadmium in milk and mammary gland in rats and mice. Arch. Toxicol. 73, 519-527.
31. Rojas P. and Rios C. (1997). Metallothionein inducers protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice. Neurochem. Res. 22, 17-22.
32. Ronco A.M., Arguello G., Muñoz L., Gras M. and Llanos M.N. (2005). Metals content in placentas from moderate cigarette consumers: correlation with new born birth weight. Biometals 18, 233-241.
33. Ronco A.M., Garrido F. and Llanos M.N. (2006). Smoking specifically induces metallothionein-2 isoform in human placenta at term. Toxicology 223, 46-53.
34. Salvatori F., Talassi C.B., Salzgeber S.A., Spinosa H.S. and Bernardi M.M. (2004). Embryotoxic and long-term effects of cadmium exposure during embryogenesis in rats. Neurotoxicol. Teratol. 26, 673-680.
35. Shennan D.B. and Boyd C.A. (1988). Placental handling of trace elements. Placenta 9, 333-343.
36. Sorkun H.C., Bir F., Akbulut M., Divrikli U., Erken G., Demirhan H., Duzcan E., Elci L., Celik I. and Yozgatli U. (2007). The effects of air pollution and smoking on placental cadmium, zinc concentration and metallothionein expression. Toxicology 238, 15-22.
37. Sorell T.L. and Graziano J.H. (1990). Effect of oral cadmium exposure during pregnancy on maternal and fetal zinc metabolism in the rat. Toxicol. Appl. Pharmacol. 102, 537-545.
38. Stoeppler M. and Brandt K. (1980). Determination of cadmium in whole blood and urine by electrothermal atomicabsorption spectrophotometry. Fresenius Z. Anal. Chem. 300, 372-380.
39. Trottier B., Athot J., Ricard A.C. and Lafond J. (2002). Maternal-fetal distribution of cadmium in the guinea pig following a low dose inhalation exposure. Toxicol. Lett. 129, 189-197.
40. Villeda-Hernandez J., Méndez-Armenta M., Barroso-Moguel R., Trejo-Solis M.C., Guevara J. and Rios C (2006). Morphometric analysis of brain lesions in rat fetuses prenatally exposed to low-level lead acetate: correlation with lipid peroxidation. Histol. Histopathol. 21, 609-617.
41. Wade J.V., Agrawal P.R. and Poisner A.M. (1986) Induction of metallothionein in a human trophoblast cell line by cadmium and zinc. Life Sci. 39, 1361-1366.
42. Wier P.J., Miller R.K., Maulik D. and DiSant'Agnese P.A. (1990). Toxicity of cadmium in the perfused human placenta. Toxicol. Appl. Pharmacol. 105, 156-171.