Reversed phase HPLC determination of zidovudine in rat plasma and its pharmacokinetics after a single intranasal dose administration

Biological Research

Volumn 42, Issue 3, 2009, Pages 357-364

  Mainardes, Rubiana M ^a   Gremião, Maria Palmira D ^b  

^a UNIVERSIDADE ESTADUAL DO CENTRO OESTE   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

AZT; Intranasal delivery; Pharmacokinetics; RP HPLC; Validation

Indexed keywords

ADMINISTRATION, INTRANASAL; ANIMALS; ANTI-RETROVIRAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MALE; RATS; RATS, WISTAR; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY, ULTRAVIOLET; ZIDOVUDINE;

RATTUS;

EID: 73349096602     PISSN: 07169760     EISSN: 07176287     Source Type: Journal    
DOI: 10.4067/S0716-97602009000300010     Document Type: Article

References (29)

1. ALNOUTI Y, LEWIS SR, WHITE CA, BARTLETT MG (2005) Simultaneous determination of zidovudine and lamivudine from rat tissues by liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom 19: 503-508
2. ALNOUTI Y, WHITE CA, BARTLETT MG (2004) Simultaneous quantitation of zidovudine and zidovudine monophosphate from plasma, amniotic fluid and tissues by micellar capillary electrophoresis. Biomed Chromatogr 18: 523-531
3. ALNOUTI Y, WHITE CA, BARTLETT MG (2004) Simultaneous determination of zidovudine and lamivudine from rat plasma, amniotic fluid and tissues by HPLC. Biomed Chromatogr 18: 641-647
4. ANVISA. Agência Nacional de Vigilância Sanitária (ANVISA). Resolução RE no 899, de 29 de maio de 2003. Diário Oficial da União, Brasília, DF, 02 Maio 2003
5. AYMARD G, LEGRAND M, TRICHEREAU N, DIQUET B (2000) Determination of twelve antiretroviral agents in human plasma sample using reversed-phase high-performance liquid chromatography. J Chromatogr B: Biomed Sci Appl 744: 227-240
6. BAIG MV, GAPSE GS, RAJU SA (2001). Spectrophotometric Determination of Lamivudine. Asian J Chem 13: 185-189
7. BLUM MR, LIAO SHT, GOOD SS, MIRANDA P (1988). Pharmacokinetics and bioavailability of zidovudine in humans. Am. J. Med 85: 189-194
8. BRITISH PHARMACOPOEIA. LONDON: THE STATIONERY OFFICE, 2001. v. 2, p.A437-A8
9. CHIEN YW, WEARLEY LL (1989) Aids and chemotherapy. Drugs of Today 25: 19-25
10. CLARK TN, WHITE CA, CHU CK, BARTLETT MG (2001) Determination of 3'-Azido-2',3' Dideoxyuridine (AZDU) in Maternal Plasma, Amniotic Fluid, Fetal and Placental Tissues by High Performance Liquid Chromatography. J Chromatog B: Biomed Sci Appl 755: 165-172
11. CLERQ ED (2004) Antiviral drugs in current clinical use. J Clin Virol 30: 115-133
12. ERK N (2004) Derivative-differential UV spectrophotometry and compensation technique for the simultaneous determination of zidovudine and lamivudine in human serum. Pharmazie 59: 106-111 International Conference on Harmonisation (ICH); Validation of Analytical Procedures: Text and Methodology, Q2 (R1), 2005
13. KENNEY KB, WRING SA, CARR RM, WELLS GN, DUNN JA (2000) Simultaneous determination of zidovudine and lamivudine in human serum using HPLC with tandem mass spectrometry. J Pharm Biomed Anal 22: 967-983
14. LEFEBVRE I, PUY JY, PERRIN C, PÉRIGAUD C (2007) Quantification of zidovudine and its monophosphate in cell extracts by on-line solid-phase extraction coupled to liquid chromatography. J Chromatog B: Anal Tech Biomed Life Sci 858: 2-7
15. LEWIS SR, WHITE CA, BARTLETT MG (2007) Simultaneous Determination of Abacavir and Zidovudine From Rat Tissues Using HPLC With Ultraviolet Detection. J Chromatog B 850: 45-52. J Chromatog B: Anal Tech Biomed Life Sci 850: 45-52
16. MANDAL TK, TENJARLA S (1996) Preparation of biodegradable microcapsules of zidovudine using solvent evaporation: Effect of the modification of aqueous phase. Int J Pharm 137: 187-197
17. MARCHEI E, VALVO L, PACIFICI R, PELLEGRINI M, TOSSINI G, ZUCCARO P (2002) Simultaneous determination of zidovudine and nevirapine in human plasma by RP-LC. J Pharm Biomed Anal 29: 1081-1088
18. MOLEMA G, JANSEN RW, VISSER J, MEIJER DK (1992) Simultaneous analysis of azidothymidine and its mono-, di- and triphosphate derivatives in biological fluids, tissue and cultured cells by a rapid high-performance liquid chromatographic method. J Chromatog 579: 107-114
19. MUDIGONDA K, JUKANTI R, APTE SS, KISHAN V, MAURYA S, KANDIKERE V, NIROGI R (2008) Rapid and simple liquid chromatography tandem mass spectrometry method for the quantification of zidovudine in rat plasma. Biomed Chromatog 22: 20-27
20. OH, SY, JEONG SY, PARK TG, LEE JH (1998) Enhanced transdermal delivery of AZT (Zidovudine) using iontophoresis and penetration enhancer. J Control Release 51: 161-168
21. PEREIRA AS, KENNEY KB, COHEN MS, HALL JE, ERON JJ, TIDWELL RR, DUNN JA (2000) Simultaneous determination of lamivudine and zidovudine concentrations in human seminal plasma using high-performance liquid chromatography and tandem mass spectrometry. J Chromatog B: Biomed Sci Appl 742: 173-183
22. RAMACHANDRAN G, HEMANTHKUMAR AK, KUMARASWAMI V, SWAMINATHAN S (2006) A simple and rapid liquid chromatography method for simultaneous determination of zidovudine and nevirapine in plasma. J Chromatog B: Anal Tech Biomed Life Sci 843: 339-344
23. SCHRIVE I, PLASSE JC (1994) Quantification of zidovudine and one of its metabolites in plasma and urine by solid-phase extraction and highperformance liquid chromatography. J Chromatog B: Biomed Sci Appl 657: 233-237
24. SHAH VP, MIDHA KK, DIGHE S, MC GILVERAY IJ, SKELLY JP, YACOBI A et al (1992) Analytical methods validation: Bioavailability, bioequivalence and pharmacokinetic studies. Int J Pharm 82: 1-7
25. TAN X, BOUDINOT FD (2000) Simultaneous determination of zidovudine and its monophosphate in mouse plasma and peripheral red blood cells by high-performance liquid chromatography. J Chromatog B: Biomed Sci Appl 740: 281-287
26. TARINAS A, TÁPANES, RD, FERRER, G, PÉREZ, J (2007) Validation of high-performance liquid chromatography methods for determination of zidovudine, stavudine, lamivudine and indinavir in human plasma. Farm Hosp 31: 243-247
27. THOMAS NS, PANCHAGNULA R (2003) Transdermal delivery of zidovudine: effect of vehicles on permeation across rat skin and their mechanism of action. Eur J Pharm Sci 18: 71-79
28. USP. United States Pharmacopeia. 27th. ed. Rockville: United States Pharmacopeial Convention, 2004. p. 2622-2625
29. YARCHOAN R, MITSUYA H, MYERS CE, BRODER S (1989) Clinical pharmacology of 3'-azido-2,3-dideoxythymidine (zidovudine) and related dideoxynucleosides. New Engl J Med 321: 726-738.