Characterization of P2X7 purinergic receptors and their function in rat lacrimal gland

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 12, 2009, Pages 5681-5689

  Hodges, Robin R ^a   Vrouvlianis, Joanna ^a   Shatos, Marie A ^a   Dartt, Darlene A ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3' O (4 BENZOYLBENZOYL)ADENOSINE TRIPHOSPHATE; A 438079; BRILLIANT BLUE; CALCIUM ION; FURA 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXIDASE; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2X7 RECEPTOR INHIBITOR; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; CALCIUM; MAPK1 PROTEIN, RAT; PURINERGIC P2 RECEPTOR;

ACINAR CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DUCTAL CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FLUORESCENCE IMAGING; IMMUNOFLUORESCENCE; LACRIMAL GLAND; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL MEMBRANE; FLUORESCENT ANTIBODY TECHNIQUE; LACRIMAL APPARATUS; MALE; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANIMALS; BLOTTING, WESTERN; CALCIUM; CELL MEMBRANE; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FURA-2; LACRIMAL APPARATUS; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 73349083977     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-3670     Document Type: Article

References (28)

1. Hodges RR, Dartt DA. Regulatory pathways in lacrimal gland epithelium. Int Rev Cytol. 2003;231:129-196.
2. Dartt DA, Baker AK, Vaillant C, et al. Vasoactive intestinal polypeptide stimulation of protein secretion from rat lacrimal gland acini. Am J Physiol. 1984;247(pt 1):G502-G509.
3. Dartt DA, Dicker DM, Ronco LV, et al. Lacrimal gland inositol trisphosphate isomer and inositol tetrakisphosphate production. Am J Physiol. 1990;259(pt 1):G274-G281.
4. Hodges RR, Dicker DM, Rose PE, et al. Alpha 1-adrenergic and cholinergic agonists use separate signal transduction pathways in lacrimal gland. Am J Physiol. 1992;262(pt 1):G1087-G1096.
5. 2+, Pyk2, and c-Src in agonist activation of rat lacrimal gland p42/p44 MAPK. Invest Ophthalmol Vis Sci. 2006;47(8):3352-3359.
6. Ota I, Zoukhri D, Hodges RR, et al. Alpha 1-adrenergic and cholinergic agonists activate MAPK by separate mechanisms to inhibit secretion in lacrimal gland. Am J Physiol Cell Physiol. 2003;284(1): C168-C178.
7. Hodges RR, Shatos MA, Tarko RS, et al. Nitric oxide and cGMP mediate alpha1D-adrenergic receptor-stimulated protein secretion and p42/p44 MAPK activation in rat lacrimal gland. Invest Ophthalmol Vis Sci. 2005;46(8):2781-2789.
8. Burnstock G. Purine and pyrimidine receptors. Cell Mol Life Sci. 2007;64(12):1471-1483.
9. Dubyak GR. Go it alone no more-P2X7 joins the society of heteromeric ATP-gated receptor channels. Mol Pharmacol. 2007; 72(6):1402-1405.
10. Bianco F, Pravettoni E, Colombo A, et al. Astrocyte-derived ATP induces vesicle shedding and IL-1/3 release from microglia. J Immunol. 2005;174(11):7268-7277.
11. Surprenant A, Rassendren F, Kawashima E, et al. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science. 1996;272(5262):735-738.
12. Donnelly-Roberts DL, Jarvis MF. Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states. Br J Pharmacol. 2007; 151(5):571-579.
13. Shibuya I, Tanaka K, Hattori Y, et al. Evidence that multiple P2X purinoceptors are functionally expressed in rat supraoptic neurones. J Physiol. 1999;514(pt 2):351-367.
14. Hodges RR, Horikawa Y, Rios JD, et al. Effect of protein kinase C and Ca(2+) on p42/p44 MAPK, Pyk2, and Src activation in rat conjunctival goblet cells. Exp Eye Res. 2007;85(6):836-844.
15. Tepavcevic V, Hodges RR, Zoukhri D, et al. Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland. Invest Ophthalmol Vis Sci. 2003;44(3):1075-1081.
16. McMillian MK, Soltoff SP, Cantley LC, et al. Two distinct cytosolic calcium responses to extracellular ATP in rat parotid acinar cells. Br J Pharmacol. 1993;108(2):453-461.
17. Nakamoto T, Brown DA, Catalan MA, et al. Purinergic P2X7 receptors mediate ATP-induced saliva secretion by the mouse submandibular gland. J Biol Chem. 2009;284(8):4815-4822.
18. Michel AD, Chessell IP, Humphrey PP. Ionic effects on human recombinant P2X7 receptor function. Naunyn Schmiedebergs Arch Pharmacol. 1999;359(2):102-109.
19. Jerdeva GV, Wu K, Yarber FA, et al. Actin and non-muscle myosin II facilitate apical exocytosis of tear proteins in rabbit lacrimal acinar epithelial cells. J Cell Sci. 2005;118(pt 20):4797-4812.
20. Li X, Gorodeski GI. Apically sorted P2X7 receptors mediate puri-nergic-induced pore formation preferentially in apical domains of the plasma membrane. Nucleosides Nucleotides Nucleic Acids. 2006;25(9-11):1045-1049.
21. Richardson PJ, Brown SJ. ATP release from affinity-purified rat cholinergic nerve terminals. J Neurochem. 1987;48(2):622-630.
22. Fitz JG. Regulation of cellular ATP release. Trans Am Clin Climatol Assoc. 2007;118:199-208.
23. Wan J, Ristenpart WD, Stone HA. Dynamics of shear-induced ATP release from red blood cells. Proc Natl Acad Sci U S A. 2008; 105(43):16432-16437.
24. Franco R, Panayiotidis MI, de la Paz LD. Autocrine signaling involved in cell volume regulation: the role of released transmitters and plasma membrane receptors. J Cell Physiol. 2008;216(1):14-28.
25. Elliott JI, Higgins CF. Major histocompatibility complex class I shedding and programmed cell death stimulated through the proinflammatory P2X7 receptor: a candidate susceptibility gene for NOD diabetes. Diabetes. 2004;53(8):2012-2017.
26. Taylor SR, Gonzalez-Begne M, Dewhurst S, et al. Sequential shrinkage and swelling underlie P2X7-stimulated lymphocyte phospha-tidylserine exposure and death. J Immunol. 2008;180(1):300-308.
27. Rampe D, Wang L, Ringheim GE. P2X7 receptor modulation of beta-amyloid- and LPS-induced cytokine secretion from human macrophages and microglia. J Neuroimmunol. 2004;147(1-2):56-61.
28. Edman MC, Andersson SV, Delbro D, et al. Functional expression of the adenosine A1 receptor in rabbit lacrimal gland. Exp Eye Res. 2008;86(1):110-117.