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Volumn 52, Issue 11, 2009, Pages 1081-1090

Metabonomic phenotype and identification of "heart blood stasis obstruction pattern" and "qi and yin deficiency pattern" of myocardial ischemia rat models

Author keywords

GC TOF MS; Heart blood stasis obstruction pattern; Metabonomics; Myocardial ischemia; Qi and yin deficiency pattern; Rat model

Indexed keywords

AMINO ACID; BIOLOGICAL MARKER;

EID: 73249141246     PISSN: 10069305     EISSN: 18622798     Source Type: Journal    
DOI: 10.1007/s11427-009-0136-y     Document Type: Article
Times cited : (27)

References (42)
  • 3
    • 0036913503 scopus 로고    scopus 로고
    • Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabolomics
    • Brindle J T, Antti H, Holmes E, et al. Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabolomics. Nat Med, 2002, 8: 1439-1444.
    • (2002) Nat Med , vol.8 , pp. 1439-1444
    • Brindle, J.T.1    Antti, H.2    Holmes, E.3
  • 4
    • 33644874718 scopus 로고    scopus 로고
    • Metabolomic identification of novel biomarkers of myocardial ischemia
    • Sabatine M S, Liu E, Morrow D A, et al. Metabolomic identification of novel biomarkers of myocardial ischemia. Circulation, 2005, 112: 3868-3875.
    • (2005) Circulation , vol.112 , pp. 3868-3875
    • Sabatine, M.S.1    Liu, E.2    Morrow, D.A.3
  • 5
    • 33845314350 scopus 로고    scopus 로고
    • Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors
    • Denkert C, Budczies J, Kind T, et al. Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors. Cancer Res, 2006, 66: 10795-10804.
    • (2006) Cancer Res , vol.66 , pp. 10795-10804
    • Denkert, C.1    Budczies, J.2    Kind, T.3
  • 6
    • 33748316468 scopus 로고    scopus 로고
    • Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS)
    • Yin P, Zhao X, Li Q, et al. Metabonomics study of intestinal fistulas based on ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS). J Proteome Res, 2006, 5: 2135-2143.
    • (2006) J Proteome Res , vol.5 , pp. 2135-2143
    • Yin, P.1    Zhao, X.2    Li, Q.3
  • 7
    • 33644835571 scopus 로고    scopus 로고
    • High performance liquid chromatography-mass spectrometry for metabonomics: Potential biomarkers for acute deterioration of liver function in chronic hepatitis B
    • Yang J, Zhao X, Liu X, et al. High performance liquid chromatography-mass spectrometry for metabonomics: potential biomarkers for acute deterioration of liver function in chronic hepatitis B. J Proteome Res, 2006, 5: 554-561.
    • (2006) J Proteome Res , vol.5 , pp. 554-561
    • Yang, J.1    Zhao, X.2    Liu, X.3
  • 8
    • 29144486833 scopus 로고    scopus 로고
    • Metabonomic study on the biochemical profiles of a hydrocortisone-induced animal model
    • Chen M, Zhao L, Jia W. Metabonomic study on the biochemical profiles of a hydrocortisone-induced animal model. J Proteome Res, 2005, 4: 2391-2396.
    • (2005) J Proteome Res , vol.4 , pp. 2391-2396
    • Chen, M.1    Zhao, L.2    Jia, W.3
  • 9
    • 21644479604 scopus 로고    scopus 로고
    • Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis
    • Wang C, Kong H, Guan Y, et al. Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass spectrometry and multivariate statistical analysis. Anal Chem, 2005, 77: 4108-4116.
    • (2005) Anal Chem , vol.77 , pp. 4108-4116
    • Wang, C.1    Kong, H.2    Guan, Y.3
  • 10
    • 41149099000 scopus 로고    scopus 로고
    • Symbiotic gut microbes modulate human metabolic phenotypes
    • Li M, Wang B, Zhang M, et al. Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci USA, 2008, 105: 2117-2122.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2117-2122
    • Li, M.1    Wang, B.2    Zhang, M.3
  • 11
    • 34249689721 scopus 로고    scopus 로고
    • Metabonomic study of syndrome of liver qi stagnation and spleen deficiency in rats (in Chinese)
    • Luo G H, Ding J, Yue G X, et al. Metabonomic study of syndrome of liver qi stagnation and spleen deficiency in rats (in Chinese). J Chinese Integr Med, 2007, 5: 307-313.
    • (2007) J Chinese Integr Med , vol.5 , pp. 307-313
    • Luo, G.H.1    Ding, J.2    Yue, G.X.3
  • 12
    • 41549089245 scopus 로고    scopus 로고
    • NMR-based metabonomics of "Qi vacuity blood stasis pattern" rat urine
    • Li L, Wang J N, Ren J X. NMR-based metabonomics of "Qi vacuity blood stasis pattern" rat urine. Chinese Sci Bull (in Chinese), 2007, 52: 1758-1762.
    • (2007) Chinese Sci Bull (in Chinese) , vol.52 , pp. 1758-1762
    • Li, L.1    Wang, J.N.2    Ren, J.X.3
  • 14
    • 0037728732 scopus 로고    scopus 로고
    • Changes of adrenomedullin and receptor activity modifying protein 2 (RAMP2) in myocardium and aorta in rats with isoproterenol-induced myocardial ischemia
    • Qi Y F, Shi Y R, Bu D F, et al. Changes of adrenomedullin and receptor activity modifying protein 2 (RAMP2) in myocardium and aorta in rats with isoproterenol-induced myocardial ischemia. Peptides, 2003, 24: 463-468.
    • (2003) Peptides , vol.24 , pp. 463-468
    • Qi, Y.F.1    Shi, Y.R.2    Bu, D.F.3
  • 15
    • 73249133432 scopus 로고
    • Research on pathological models of "blood stasis" (1)
    • Mao T M, Lin J H. Research on pathological models of "blood stasis" (1). J Beijing Med Univ (in Chinese), 1985, 17: 246-248.
    • (1985) J Beijing Med Univ (in Chinese) , vol.17 , pp. 246-248
    • Mao, T.M.1    Lin, J.H.2
  • 16
    • 73249142162 scopus 로고    scopus 로고
    • Study on normalization and standardization of animal models with TCM "pattern" myocardial ischemia (2)
    • Zhang C, Sheng X S, Lv R, et al. Study on normalization and standar-dization of animal models with TCM "pattern" myocardial ischemia (2). Shanghai J Trad Chinese Med (in Chinese), 2003, 37: 42-45.
    • (2003) Shanghai J Trad Chinese Med (in Chinese) , vol.37 , pp. 42-45
    • Zhang, C.1    Sheng, X.S.2    Lv, R.3
  • 17
    • 29344435772 scopus 로고    scopus 로고
    • Extraction and GC/MS analysis of the human blood plasma metabolome
    • A J Trygg J, Gullberg J, Johanssson A I, et al. Extraction and GC/MS analysis of the human blood plasma metabolome. Anal Chem, 2005, 77: 8086-8094.
    • (2005) Anal Chem , vol.77 , pp. 8086-8094
    • Trygg, A.J.J.1    Gullberg, J.2    Johanssson, A.I.3
  • 18
    • 24644481093 scopus 로고    scopus 로고
    • High-Throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses
    • Jonsson P, Johansson A I, Gullberg J, et al. High-Throughput data analysis for detecting and identifying differences between samples in GC/MS-based metabolomic analyses. Anal Chem, 2005, 77: 5635-5642.
    • (2005) Anal Chem , vol.77 , pp. 5635-5642
    • Jonsson, P.1    Johansson, A.I.2    Gullberg, J.3
  • 19
    • 33847369007 scopus 로고    scopus 로고
    • Chemometrics techniques for metabonomics
    • Trygg J, Lundstedt T. Chemometrics techniques for metabonomics. J Proteome Res, 2007, 6: 469-479.
    • (2007) J Proteome Res , vol.6 , pp. 469-479
    • Trygg, J.1    Lundstedt, T.2
  • 20
    • 84951601886 scopus 로고
    • Cross-validatory estimation of the number of components in factor and principal components models
    • Wold S. Cross-validatory estimation of the number of components in factor and principal components models. Technometrics, 1978, 20: 397-405.
    • (1978) Technometrics , vol.20 , pp. 397-405
    • Wold, S.1
  • 21
    • 73249122134 scopus 로고    scopus 로고
    • Beijing: People's Medical Publishing House
    • Wu W T. Biochemistry. Beijing: People's Medical Publishing House, 2001.
    • (2001) Biochemistry
    • Wu, W.T.1
  • 22
    • 0035350549 scopus 로고    scopus 로고
    • Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain
    • Silva A R, Ruschel C, Helegda C, et al. Inhibition of in vitro CO2 production and lipid synthesis by 2-hydroxybutyric acid in rat brain. Braz J Med Biol Res, 2001, 34: 627-631.
    • (2001) Braz J Med Biol Res , vol.34 , pp. 627-631
    • Silva, A.R.1    Ruschel, C.2    Helegda, C.3
  • 23
    • 0036016029 scopus 로고    scopus 로고
    • Beta-hydroxybutyrate, a cerebral function improving agent, protects rat brain against ischemic damage caused by permanent and transient focal cerebral ischemia
    • Suzuki M, Suzuki M, Kitamura Y, et al. Beta-hydroxybutyrate, a cerebral function improving agent, protects rat brain against ischemic damage caused by permanent and transient focal cerebral ischemia. Jpn J Pharmacol, 2002, 89: 36-43.
    • (2002) Jpn J Pharmacol , vol.89 , pp. 36-43
    • Suzuki, M.1    Suzuki, M.2    Kitamura, Y.3
  • 24
    • 0033931557 scopus 로고    scopus 로고
    • Increased plasma beta-hydroxybutyrate, preserved cerebral energy metabolism, and amelioration of brain damage during neonatal hypoxia ischemia with dexamethasone pretreatment
    • Dardzinski B J, Smith S L, Towfighi J, et al. Increased plasma beta-hydroxybutyrate, preserved cerebral energy metabolism, and amelioration of brain damage during neonatal hypoxia ischemia with dexamethasone pretreatment. Pediatr Res, 2000, 48: 248-255.
    • (2000) Pediatr Res , vol.48 , pp. 248-255
    • Dardzinski, B.J.1    Smith, S.L.2    Towfighi, J.3
  • 25
    • 0028929043 scopus 로고
    • Glutathione depletion in rested and exercised mice: Biochemical consequence and adaptation
    • Leeuwenburgh C, Ji L L. Glutathione depletion in rested and exercised mice: biochemical consequence and adaptation. Arch Biochem Biophys, 1995, 316: 941-949.
    • (1995) Arch Biochem Biophys , vol.316 , pp. 941-949
    • Leeuwenburgh, C.1    Ji, L.L.2
  • 26
    • 3042802690 scopus 로고    scopus 로고
    • Glutathione: An overview of biosynthesis and modulation
    • Anderson M E. Glutathione: an overview of biosynthesis and modulation. Chem Biol Interact, 1998, 111-112: 1-14.
    • (1998) Chem Biol Interact , vol.111-112 , pp. 1-14
    • Anderson, M.E.1
  • 27
    • 0020593579 scopus 로고
    • A relationship between ascorbic acid and threonic acid in guinea-pigs
    • Thomas M, Hughes R E. A relationship between ascorbic acid and threonic acid in guinea-pigs. Food Chem Toxicol, 1983, 21: 449-452.
    • (1983) Food Chem Toxicol , vol.21 , pp. 449-452
    • Thomas, M.1    Hughes, R.E.2
  • 28
    • 1942502303 scopus 로고    scopus 로고
    • Metabolomic differential display analysis of the white-rot basidiomycete Phanerochaete chrysosporium grown under air and 100% oxygen
    • Miura D, Tanaka H, Wariishi H. Metabolomic differential display analysis of the white-rot basidiomycete Phanerochaete chrysosporium grown under air and 100% oxygen. FEMS Microbiol Lett, 2004, 234: 111-116.
    • (2004) FEMS Microbiol Lett , vol.234 , pp. 111-116
    • Miura, D.1    Tanaka, H.2    Wariishi, H.3
  • 29
    • 0031785348 scopus 로고    scopus 로고
    • Glutamine, exercise and immune function. Links and possible mechanisms
    • Walsh N P, Blannin A K, Robson P J, et al. Glutamine, exercise and immune function. Links and possible mechanisms. Sports Med, 1998, 26: 177-191.
    • (1998) Sports Med , vol.26 , pp. 177-191
    • Walsh, N.P.1    Blannin, A.K.2    Robson, P.J.3
  • 30
    • 0027630609 scopus 로고
    • Relationship between aging and hydroxyproline content of serum in human being
    • Koyama K, Sato T, Omichi N, et al. Relationship between aging and hydroxyproline content of serum in human being. Ann Physiol Anthropol, 1993, 12: 243-249.
    • (1993) Ann Physiol Anthropol , vol.12 , pp. 243-249
    • Koyama, K.1    Sato, T.2    Omichi, N.3
  • 31
    • 39149133655 scopus 로고    scopus 로고
    • Time dependent effects of gentamicin on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in rat kidney tissues
    • Banday A A, Farooq N, Priyamvada S, et al, Time dependent effects of gentamicin on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in rat kidney tissues. Life Sci, 2008, 82: 450-459.
    • (2008) Life Sci , vol.82 , pp. 450-459
    • Banday, A.A.1    Farooq, N.2    Priyamvada, S.3
  • 32
    • 42149191548 scopus 로고    scopus 로고
    • Melatonin protects against endosulfan-induced oxidative tissue damage in rats
    • Omurtag G Z, Tozan A, Sehirli A O, et al, Melatonin protects against endosulfan-induced oxidative tissue damage in rats. J Pineal Res, 2008, 44: 432-438.
    • (2008) J Pineal Res , vol.44 , pp. 432-438
    • Omurtag, G.Z.1    Tozan, A.2    Sehirli, A.O.3
  • 33
    • 23244438118 scopus 로고    scopus 로고
    • A review of the possible relevance of inositol and the phosphatidylinositol second messenger system (PI-cycle) to psychiatric disorders-focus on magnetic resonance spectroscopy (MRS) studies
    • Kim H, McGrath B M, Silverstone P H. A review of the possible relevance of inositol and the phosphatidylinositol second messenger system (PI-cycle) to psychiatric disorders-focus on magnetic resonance spectroscopy (MRS) studies. Hum Psychopharmacol, 2005, 20: 309-326.
    • (2005) Hum Psychopharmacol , vol.20 , pp. 309-326
    • Kim, H.1    McGrath, B.M.2    Silverstone, P.H.3
  • 34
    • 73249115415 scopus 로고    scopus 로고
    • Mechanism of sleep deprivation and progress in traditional Chinese medicine and materia medica intervention
    • Xing Y L, Yu L Z. Mechanism of sleep deprivation and progress in traditional Chinese medicine and materia medica intervention. Pharmacol Clin Chinese Mater Med (in Chinese), 2003, 19: 47-49.
    • (2003) Pharmacol Clin Chinese Mater Med (in Chinese) , vol.19 , pp. 47-49
    • Xing, Y.L.1    Yu, L.Z.2
  • 35
    • 41549110333 scopus 로고    scopus 로고
    • Metabonomics and its application prospect in TCM study
    • Wang G J, Zha W B, Hao H P, et al. Metabonomics and its application prospect in TCM study. Clin J Nat Med (in Chinese), 2008, 6: 89-97.
    • (2008) Clin J Nat Med (in Chinese) , vol.6 , pp. 89-97
    • Wang, G.J.1    Zha, W.B.2    Hao, H.P.3
  • 36
    • 41449092621 scopus 로고    scopus 로고
    • Metabonomics in research of natural drugs and traditional Chinese medicines
    • Liu C X, Ci D Y, Wan R Z, et al. Metabonomics in research of natural drugs and traditional Chinese medicines. Clin J Nat Med (in Chinese), 2008, 6: 82-88.
    • (2008) Clin J Nat Med (in Chinese) , vol.6 , pp. 82-88
    • Liu, C.X.1    Ci, D.Y.2    Wan, R.Z.3
  • 37
    • 33845738448 scopus 로고    scopus 로고
    • Pharmacodynamics and its biochemical mechanism of Uncaria-stem Mistura for hyperactivity syndrome by metabonomic method
    • Huang Y R, Wei G L, Long H, et al. Pharmacodynamics and its biochemical mechanism of Uncaria-stem Mistura for hyperactivity syndrome by metabonomic method. Chinese Trad Herb Drugs (in Chinese), 2005, 36: 398-402.
    • (2005) Chinese Trad Herb Drugs (in Chinese) , vol.36 , pp. 398-402
    • Huang, Y.R.1    Wei, G.L.2    Long, H.3
  • 39
    • 34948835721 scopus 로고    scopus 로고
    • Metabolic regulatory net-work alterations in response to acute cold stress and ginsenoside intervention
    • Wang X Y, Su M M, Qiu Y P, et al. Metabolic regulatory net-work alterations in response to acute cold stress and ginsenoside intervention. J Proteome Res, 2007, 6: 3449-3455.
    • (2007) J Proteome Res , vol.6 , pp. 3449-3455
    • Wang, X.Y.1    Su, M.M.2    Qiu, Y.P.3
  • 40
    • 34147133923 scopus 로고    scopus 로고
    • A pharmaco-metabonomic study on the therapeutic basis and metabolic effects of Epimedium brevicornum Maxim. on hydrocortisone-induced rat using UPLC-MS
    • Li F M, Lu X M, Liu H P, et al. A pharmaco-metabonomic study on the therapeutic basis and metabolic effects of Epimedium brevicornum Maxim. on hydrocortisone-induced rat using UPLC-MS. Biomed Chromatogr, 2007, 21: 397-405.
    • (2007) Biomed Chromatogr , vol.21 , pp. 397-405
    • Li, F.M.1    Lu, X.M.2    Liu, H.P.3
  • 41
    • 41549130870 scopus 로고    scopus 로고
    • Study on the mechanism of action of Liuwei and Bawei Dihuang decoction by metabonomics
    • Jiang N, Zhou W X, Zhang Y X. Study on the mechanism of action of Liuwei and Bawei Dihuang decoction by metabonomics. Pharmacol Clin Chinese Mater Med (in Chinese), 2007, 23: 45.
    • (2007) Pharmacol Clin Chinese Mater Med (in Chinese) , vol.23 , pp. 45
    • Jiang, N.1    Zhou, W.X.2    Zhang, Y.X.3
  • 42
    • 36949005678 scopus 로고    scopus 로고
    • Investigations into metabonomic profiling of spontaneously hypertension rat (SHR) and metabolic effects of total ginsenoside on SHR using GC/MS
    • Lu Y H, Wang G J, Huang Q, et al. Investigations into metabonomic profiling of spontaneously hypertension rat (SHR) and metabolic effects of total ginsenoside on SHR using GC/MS. Chin J Nat Med (in Chinese), 2007, 11: 443-447.
    • (2007) Chin J Nat Med (in Chinese) , vol.11 , pp. 443-447
    • Lu, Y.H.1    Wang, G.J.2    Huang, Q.3


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