Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells

Biomedicine and Pharmacotherapy

Volumn 64, Issue 1, 2010, Pages 54-57

  Pietkiewicz, P P ^a   Lutkowska, A ^a   Lianeri, M ^a   Jagodzinski, P P ^a  

^a POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Breast cancer; CXCL12; Tamoxifen

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; BISULFITE; STROMAL CELL DERIVED FACTOR 1; TAMOXIFEN;

ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA SEQUENCE; DRUG EFFECT; EPIGENETICS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; METASTASIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, HORMONAL; AZACITIDINE; BREAST NEOPLASMS; CELL LINE, TUMOR; CHEMOKINE CXCL12; CYTOSINE; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; SEQUENCE ANALYSIS, DNA; TAMOXIFEN;

EID: 73149111047     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2009.04.041     Document Type: Article

References (27)

1. Bleul C.C., Fuhlbrigge R.C., Casasnovas J.M., Aiuti A., and Springer T.A. A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1). J Exp Med 184 (1996) 1101-1109
2. Yong K., Fahey A., Reeve L., Nicholls C., Thomas N.S., Pizzey A., et al. Cord blood progenitor cells have greater transendothelial migratory activity and increased responses to SDF-1 and MIP-3beta compared with mobilized adult progenitor cells. Br J Haematol 107 (1999) 441-449
3. Hamada T., Möhle R., Hesselgesser J., Hoxie J., Nachman R.L., Moore M.A., et al. Transendothelial migration of megakaryocytes in response to stromal cell-derived factor 1 (SDF-1) enhances platelet formation. J Exp Med 188 (1998) 539-548
4. McGrath K.E., Koniski A.D., Maltby K.M., McGann J.K., and Palis J. Embryonic expression and function of the chemokine SDF-1 and its receptor CXCR4. Dev Biol 213 (1999) 442-456
5. Müller A., Homey B., Soto H., Ge N., Catron D., Buchanan M.E., et al. Involvement of chemokine receptors in breast cancer metastasis. Nature 410 (2001) 50-56
6. Luker K.E., and Luker G.D. Functions of CXCL12 and CXCR4 in breast cancer. Cancer Lett 238 (2006) 30-41
7. Hassan S., Baccarelli A., Salvucci O., and Basik M. Plasma stromal cell-derived factor-1: host derived marker predictive of distant metastasis in breast cancer. Clin Cancer Res 14 (2008) 446-454
8. Zhou W., Jiang Z., Liu N., Xu F., Wen P., Liu Y., et al. Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas. J Cancer Res Clin Oncol 135 (2009) 91-102
9. Zhou W., Jiang Z., Song X., Liu Y., and Wen P. Promoter hypermethylation-mediated down-regulation of CXCL12 in human astrocytoma. J Neurosci Res 86 (2008) 3002-3010
10. Sowińska A., and Jagodzinski P.P. RNA interference-mediated knockdown of DNMT1 and DNMT3B induces CXCL12 expression in MCF-7 breast cancer and AsPC1 pancreatic carcinoma cell lines. Cancer Lett 255 (2007) 153-159
11. Wendt M.K., Johanesen P.A., Kang-Decker N., Binion D.G., Shah V., and Dwinell M.B. Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. Oncogene 36 (2006) 4986-4997
12. Issa J.P. DNA methylation as a therapeutic target in cancer. Clin Cancer Res 13 (2007) 1634-1637
13. Key T.J., Appleby P.N., Reeves G.K., Roddam A., Dorgan J.F., Longcope C., et al. Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst 95 (2003) 1218-1226
14. Osborne C.K., Zhao H., and Fuqua S.A. Selective estrogen receptor modulators: structure, function, and clinical use. J Clin Oncol 18 (2000) 3172-3186
15. Katzenellenbogen B.S., Montano M.M., Ediger T.R., Sun J., Ekena K., Lazennec G., et al. Estrogen receptors: selective ligands, partners, and distinctive pharmacology. Recent Prog Horm Res 55 (2000) 163-193
16. Chomczyński P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
17. Szabo A., Perou C.M., Karaca M., Perreard L., Palais R., Quackenbush J.F., et al. Statistical modeling for selecting housekeeper genes. Genome Biol 5 (2004) R59
18. Frasor J., Chang E.C., Komm B., Lin C.Y., Vega V.B., Liu E.T., et al. Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome. Cancer Res 66 (2006) 7334-7340
19. Kang H., Watkins G., Parr C., Douglas-Jones A., Mansel R.E., and Jiang W.G. Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res 7 (2005) R402-R410
20. Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121 (2005) 335-348
21. Vlahakis S.R., Villasis-Keever A., Gomez T., Vanegas M., Vlahakis N., and Paya C.V. G protein-coupled chemokine receptors induce both survival and apoptotic signaling pathways. J Immunol 169 (2002) 5546-5554
22. Chang L., and Karin M. Mammalian MAP kinase signalling cascades. Nature 410 (2001) 37-40
23. Balkwill F. Chemokine biology in cancer. Semin Immunol 15 (2003) 49-55
24. Kubarek L, Kozłowska A, Przybylski M, Lianeri M, Jagodzinski PP. Down-regulation of CXCR4 expression by tamoxifen is associated with DNA methyltransferase 3B up-regulation in MCF-7 breast cancer cells. Biomed Pharmacother, doi:10.1016/j.biopha.2008.10.007.
25. Ooi S.K., and Bestor T.H. The colorful history of active DNA demethylation. Cell 133 (2008) 1145-1148
26. Kangaspeska S., Stride B., Métivier R., Polycarpou-Schwarz M., Ibberson D., Carmouche R.P., et al. Transient cyclical methylation of promoter DNA. Nature 452 (2008) 112-115
27. Métivier R., Gallais R., Tiffoche C., Le Péron C., Jurkowska R.Z., Carmouche R.P., et al. Cyclical DNA methylation of a transcriptionally active promoter. Nature 452 (2008) 45-50