Noradrenergic lesion of the locus coeruleus increases apomorphine-induced circling behavior and the firing activity of substantia nigra pars reticulata neurons in a rat model of Parkinson's disease

Brain Research

Volumn 1310, Issue , 2010, Pages 189-199

  Wang, Yong ^a   Zhang, Qiao Jun ^b   Liu, Jian ^a,c   Ali, Umar ^a   Gui, Zhen Hua ^a   Hui, Yan Ping ^b   Chen, Li ^a   Wu, Zhong Heng ^b   Li, Qiang ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b the Second Affiliated Hospital   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

Author keywords

Apomorphine; Circling behavior; Extracellular recording; Locus coeruleus; Parkinson's disease; Substantia nigra pars reticulata

Indexed keywords

APOMORPHINE; DESIPRAMINE; OXIDOPAMINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CIRCLING BEHAVIOR; CONTROLLED STUDY; HYPERACTIVITY; IN VIVO STUDY; LOCUS CERULEUS; MALE; MOTOR DYSFUNCTION; NERVE CELL EXCITABILITY; NONHUMAN; NORADRENERGIC SYSTEM; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SHAM PROCEDURE; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

ACTION POTENTIALS; ADRENERGIC AGENTS; ANIMALS; APOMORPHINE; DISEASE MODELS, ANIMAL; LOCUS COERULEUS; MALE; MOVEMENT; NEURONS; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; RATS; RATS, SPRAGUE-DAWLEY; STATISTICS, NONPARAMETRIC; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

RATTUS;

EID: 73149094500     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2009.10.070     Document Type: Article

References (62)

1. Alachkar A., Brotchie J., and Jones O. Alpha2-Adrenoceptor-mediated modulation of the release of GABA and noradrenaline in the rat substantia nigra pars reticulata. Neurosci. Lett. 395 (2006) 138-142
2. Azmitia E., and Segal M. An autoradiographic analysis of the differential ascending projections of the dorsal and median raphe nuclei in the rat. J. Comp. Neurol. 179 (1978) 641-667
3. Berretta N., Bernardi G., and Mercuri N. Alpha(1)-adrenoceptor-mediated excitation of substantia nigra pars reticulata neurons. Neuroscience 98 (2000) 599-604
4. Berridge C., and Waterhouse B. The locus coeruleus-noradrenergic system: modulation of behavioral state and state-dependent cognitive processes. Brain Res. Rev. 42 (2003) 33-84
5. Bertrand E., Lechowicz W., Szpak G., and Dymecki J. Qualitative and quantitative analysis of locus coeruleus neurons in Parkinson's disease. Folia Neuropathol. 35 (1997) 80-86
6. Blandini F., Nappi G., Tassorelli C., and Martignoni E. Functional changes of the basal ganglia circuitry in Parkinson's disease. Prog. Neurobiol. 62 (2000) 63-88
7. Breit S., Martin A., Lessmann L., Cerkez D., Gasser T., and Schulz J. Bilateral changes in neuronal activity of the basal ganglia in the unilateral 6-hydroxydopamine rat model. J. Neurosci. Res. 86 (2008) 1388-1396
8. Burbaud P., Gross C., Benazzouz A., Coussemacq M., and Bioulac B. Reduction of apomorphine-induced rotational behaviour by subthalamic lesion in 6-OHDA lesioned rats is associated with a normalization of firing rate and discharge pattern of pars reticulata neurons. Exp. Brain Res. 105 (1995) 48-58
9. Caillé S., Espejo E., Reneric J., Cador M., Koob G., and Stinus L. Total neurochemical lesion of noradrenergic neurons of the locus coeruleus does not alter either naloxone-precipitated or spontaneous opiate withdrawal nor does it influence ability of clonidine to reverse opiate withdrawal. J. Pharmacol. Exp. Ther. 290 (1999) 881-892
10. Chen L., Chan S., and Yung W. Rotational behavior and electrophysiological effects induced by GABA(B) receptor activation in rat globus pallidus. Neuroscience 114 (2002) 417-425
11. Chopin P., Colpaert F., and Marien M. Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J. Pharmacol. Exp. Ther. 288 (1999) 798-804
12. Deumens R., Blokland A., and Prickaerts J. Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp. Neurol. 175 (2002) 303-317
13. Devoto P., Flore G., Longu G., Pira L., and Gessa G. Origin of extracellular dopamine from dopamine and noradrenaline neurons in the medial prefrontal and occipital cortex. Synapse 50 (2003) 200-205
14. Devoto P., Flore G., Saba P., Castelli M., Piras A., Luesu W., Viaggi M., Ennas M., and Gessa G. 6-Hydroxydopamine lesion in the ventral tegmental area fails to reduce extracellular dopamine in the cerebral cortex. J. Neurosci. Res. 86 (2008) 1647-1658
15. Devoto P., Flore G., Saba P., Fà M., and Gessa G. Co-release of noradrenaline and dopamine in the cerebral cortex elicited by single train and repeated train stimulation of the locus coeruleus. BMC Neurosci. 6 (2005) 31-41
16. Donaldson I., Dolphin A., Jenner P., Pycock C., and Marsden C. Rotational behaviour produced in rats by unilateral electrolytic lesions of the ascending noradrenergic bundles. Brain Res. 138 (1977) 487-509
17. Díaz M., Barroso-Chinea P., Acevedo A., and González-Hernández T. Effects of dopaminergic cell degeneration on electrophysiological characteristics and GAD65/GAD67 expression in the substantia nigra: different action on GABA cell subpopulations. Mov. Disord. 18 (2003) 254-266
18. Fedrowitz M., Lindemann S., Löscher W., and Gernert M. Altered spontaneous discharge rate and pattern of basal ganglia output neurons in the circling (ci2) rat mutant. Neuroscience 118 (2003) 867-878
19. Fulceri F., Biagioni F., Ferrucci M., Lazzeri G., Bartalucci A., Galli V., Ruggieri S., Paparelli A., and Fornai F. Abnormal involuntary movements (AIMs) following pulsatile dopaminergic stimulation: severe deterioration and morphological correlates following the loss of locus coeruleus neurons. Brain Res. 1135 (2007) 219-229
20. Galvan A., and Wichmann T. Pathophysiology of parkinsonism. Clin. Neurophysiol. 119 (2008) 1459-1474
21. Gesi M., Soldani P., Giorgi F., Santinami A., Bonaccorsi I., and Fornai F. The role of the locus coeruleus in the development of Parkinson's disease. Neurosci. Biobehav. Rev. 24 (2000) 655-668
22. Grimbergen Y., Langston J., Roos R., and Bloem B. Postural instability in Parkinson's disease: the adrenergic hypothesis and the locus coeruleus. Expert. Rev. Neurother. 9 (2009) 279-290
23. Hanrott K., Gudmunsen L., O'Neill M., and Wonnacott S. 6-Hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase C delta. J. Biol. Chem. 281 (2006) 5373-5382
24. Jones B., and Moore R. Ascending projections of the locus coeruleus in the rat. II. Autoradiographic study. Brain Res. 127 (1977) 25-53
25. Kish S., Shannak K., and Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications. N. Engl. J. Med. 318 (1988) 876-880
26. Kondoh T., Bannai M., Nishino H., and Torii K. 6-Hydroxydopamine-induced lesions in a rat model of hemi-Parkinson's disease monitored by magnetic resonance imaging. Exp. Neurol. 192 (2005) 194-202
27. Lategan A., Marien M., and Colpaert F. Effects of locus coeruleus lesions on the release of endogenous dopamine in the rat nucleus accumbens and caudate nucleus as determined by intracerebral microdialysis. Brain Res. 523 (1990) 134-138
28. Lategan A., Marien M., and Colpaert F. Suppression of nigrostriatal and mesolimbic dopamine release in vivo following noradrenaline depletion by DSP-4: a microdialysis study. Life Sci. 50 (1992) 995-999
29. Lee A., Wissekerke A., Rosin D., and Lynch K. Localization of alpha2C-adrenergic receptor immunoreactivity in catecholaminergic neurons in the rat central nervous system. Neuroscience 84 (1998) 1085-1096
30. Lee C., Abercrombie E., and Tepper J. Pallidal control of substantia nigra dopaminergic neuron firing pattern and its relation to extracellular neostriatal dopamine levels. Neuroscience 129 (2004) 481-489
31. Lee C., Sauer H., and Bjorklund A. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience 72 (1996) 641-653
32. 2 agonist in hemiparkinsonian rats after repeated administration of apomorphine. J. Korean Med. Sci. 16 (2001) 636-642
33. Lindvall O., and Björklund A. The organization of the ascending catecholamine neuron systems in the rat brain as revealed by the glyoxylic acid fluorescence method. Acta Physiol. Scand. Suppl. 412 (1974) 1-48
34. Löscher W., Rohlfs A., and Rundfeldt C. Reduction in firing rate of substantia nigra pars reticulata neurons by valproate: influence of different types of anesthesia in rats. Brain Res. 702 (1995) 133-144
35. Marin C., Aguilar E., and Bonastre M. Effect of locus coeruleus denervation on levodopa-induced motor fluctuations in hemiparkinsonian rats. J. Neural. Transm. 115 (2008) 1133-1139
36. 1 receptors on striatonigral terminals via a pertussis toxin-sensitive coupling pathway. J. Neurosci. 14 (1994) 4494-4506
37. Mavridis M., Degryse A., Lategan A., Marien M., and Colpaert F. Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: a possible role for the locus coeruleus in the progression of Parkinson's disease. Neuroscience 41 (1991) 507-523
38. Morency M., Stewart R., and Beninger R. Circling behavior following unilateral microinjections of cocaine into the medial prefrontal cortex: dopaminergic or local anesthetic effect?. J. Neurosci. 7 (1987) 812-818
39. Murer M., Riquelme L., Tseng K., and Pazo J. Substantia nigra pars reticulata single unit activity in normal and 6-OHDA-lesioned rats: effects of intrastriatal apomorphine and subthalamic lesions. Synapse 27 (1997) 278-293
40. Parent A., Côté P., and Lavoie B. Chemical anatomy of primate basal ganglia. Prog. Neurobiol. 46 (1995) 131-197
41. 2-like dopamine receptors synergistically activate rotation and c-fos expression in the dopamine-depleted striatum in a rat model of Parkinson's disease. J. Neurosci. 12 (1992) 3729-3742
42. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 5th ed (2005), Elsevier Academic Press, New York
43. Pelled G., Bergman H., and Goelman G. Functional magnetic resonance imaging studies of the rat model of Parkinson's disease. Proc. Intl. Soc. Mag. Reson. Med. 8 (2000) 922
44. Pycock C., Donaldson I., and Marsden C. Circling behaviour produced by unilateral lesions in the region of the locus coeruleus in rats. Brain Res. 97 (1975) 317-329
45. 2 dopamine agonists on turning behaviour in rats. Brain Res. 384 (1986) 387-390
46. Rohlfs A., Nikkhah G., Rosenthal C., Rundfeldt C., Brandis A., Samii M., and Löscher W. Hemispheric asymmetries in spontaneous firing characteristics of substantia nigra pars reticulata neurons following a unilateral 6-hydroxydopamine lesion of the rat nigrostriatal pathway. Brain Res. 761 (1997) 352-356
47. Rommelfanger K., Edwards G., Freeman K., Liles L., Miller G., and Weinshenker D. Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice. Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 13804-13809
48. Rommelfanger K., Mitrano D., Smith Y., and Weinshenker D. Light and electron microscopic localization of alpha-1 adrenergic receptor immunoreactivity in the rat striatum and ventral midbrain. Neuroscience 158 (2009) 1530-1540
49. Rommelfanger K., and Weinshenker D. Norepinephrine: the redheaded stepchild of Parkinson's disease. Biochem. Pharmacol. 74 (2007) 177-190
50. Rückert N., Bubser M., and Schmidt W. 6-Hydroxydopamine lesion of locus coeruleus and the antiparkinsonian potential of NMDA-receptor antagonists in rats. J. Neural. Transm. 104 (1997) 363-377
51. Schwarting R., and Huston J. The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments. Prog. Neurobiol. 50 (1996) 275-331
52. Schwarting R., and Huston J. Unilateral 6-hydroxydopamine lesions of meso-striatal dopamine neurons and their physiological sequelae. Prog. Neurobiol. 49 (1996) 215-266
53. Srinivasan J., and Schmidt W. Potentiation of parkinsonian symptoms by depletion of locus coeruleus noradrenaline in 6-hydroxydopamine-induced partial degeneration of substantia nigra in rats. Eur. J. Neurosci. 17 (2003) 2586-2592
54. A receptor-mediated inhibition of rat substantia nigra dopaminergic neurons by pars reticulata projection neurons. J. Neurosci. 15 (1995) 3092-3103
55. Thiel A., Hilker R., Kessler J., Habedank B., Herholz K., and Heiss W. Activation of basal ganglia loops in idiopathic Parkinson's disease: a PET study. J. Neural. Transm. 110 (2003) 1289-1301
56. Vanderwolf C., and Baker G. The role of brain noradrenaline in cortical activation and behavior: a study of lesions of the locus coeruleus, medial thalamus and hippocampus-neocortex and of muscarinic blockade in the rat. Behav. Brain Res. 78 (1996) 225-234
57. Vila M., Levy R., Herrero M., Ruberg M., Faucheux B., Obeso J., Agid Y., and Hirsch E. Consequences of nigrostriatal denervation on the functioning of the basal ganglia in human and nonhuman primates: an in situ hybridization study of cytochrome oxidase subunit I mRNA. J. Neurosci. 17 (1997) 765-773
58. 1A receptor stimulation in the rat. Neuroscience 159 (2009) 850-861
59. Wang T., Zhang Q.J., Liu J., Wu Z.H., and Wang S. Firing activity of locus coeruleus noradrenergic neurons increases in a rodent model of Parkinsonism. Neurosci. Bull. 25 (2009) 15-20
60. Wichmann T., Bergman H., Starr P., Subramanian T., Watts R., and DeLong M. Comparison of MPTP-induced changes in spontaneous neuronal discharge in the internal pallidal segment and in the substantia nigra pars reticulata in primates. Exp. Brain Res. 125 (1999) 397-409
61. Ziegler M., and Szechtman H. Differences in the behavioral profile of circling under amphetamine and apomorphine in rats with unilateral lesions of the substantia nigra. Behav. Neurosci. 102 (1988) 276-288
62. Ziegler M., and Szechtman H. Relation between motor asymmetry and direction of rotational behaviour under amphetamine and apomorphine in rats with unilateral degeneration of the nigrostriatal dopamine system. Behav. Brain Res. 39 (1990) 123-133