Purification and biological activity of the thrombin-like substance isolated from Bothrops insularis venom

Toxicon

Volumn 49, Issue 3, 2007, Pages 329-338

  Braga, Marcus Davis Machado ^a   Martins, Alice Maria Costa ^a   de Menezes, Dalgimar Bezerra ^a   Barbosa, Paulo Sergio Ferreira ^a   Evangelista, Janaina Serra Azul Monteiro ^a   Toyama, Marcos Hikari ^b   Toyama, Daniela Oliveira ^b   Fonteles, Manassés Claudino ^c   Monteiro, Helena Serra Azul ^a  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c MACKENZIE PRESBYTERIAN UNIVERSITY   (Brazil)

Author keywords

Biological activity; Bothrops insularis; Renal activity; Thrombin like substance

Indexed keywords

2 DIETHYLAMINOETHANOL; BENZAMIDINE; BOTHROPS INSULARIS VENOM; CHLORIDE; GLUCOSE; LECTIN; POTASSIUM; SNAKE VENOM; THROMBIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CELL ISOLATION; CHROMATOGRAPHY; CONTROLLED STUDY; FRACTIONATION; GLOMERULUS FILTRATION RATE; INSULIN RELEASE; ISOLATION AND PURIFICATION; KIDNEY FUNCTION; KIDNEY TUBULE ABSORPTION; KIDNEY VASCULAR RESISTANCE; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PERFUSION PRESSURE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SODIUM ABSORPTION; URINE FLOW RATE;

ANIMALS; BLOOD COAGULATION; BOTHROPS; CELLS, CULTURED; CHLORIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROTALID VENOMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLOMERULAR FILTRATION RATE; HEMOSTATICS; INSULIN; INSULIN-SECRETING CELLS; KIDNEY; KIDNEY TUBULES; LECTINS; MALE; PERFUSION; RATS; RATS, WISTAR; URINATION; VASCULAR RESISTANCE;

BOTHROPS INSULARIS; BOTHROPS JARARACA; RATTUS; RATTUS NORVEGICUS;

EID: 33846585382     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.10.005     Document Type: Article

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