메뉴 건너뛰기




Volumn 69, Issue 1, 2010, Pages 38-50

Inosine monophosphate dehydrogenase variability in renal transplant patients on long-term mycophenolate mofetil therapy

Author keywords

IMPDH; Mycophenolic acid; Pharmacodynamics; Pharmacokinetics; Rejection; Renal transplant

Indexed keywords

INOSINATE DEHYDROGENASE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

EID: 72949123024     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2009.03542.x     Document Type: Article
Times cited : (38)

References (41)
  • 1
    • 0029917782 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolate mofetil (RS61443): A short review
    • Bullingham RE, Nicholls A, Hale M. Pharmacokinetics of mycophenolate mofetil (RS61443): a short review. Transplant Proc 1996 28 : 925 929.
    • (1996) Transplant Proc , vol.28 , pp. 925-929
    • Bullingham, R.E.1    Nicholls, A.2    Hale, M.3
  • 3
    • 0023697556 scopus 로고
    • Cloning and sequence analysis of the human and Chinese hamster inosine-5′-monophosphate dehydrogenase cDNAs
    • Collart FR, Huberman E. Cloning and sequence analysis of the human and Chinese hamster inosine-5′-monophosphate dehydrogenase cDNAs. J Biol Chem 1988 263 : 15769 15772.
    • (1988) J Biol Chem , vol.263 , pp. 15769-15772
    • Collart, F.R.1    Huberman, E.2
  • 5
    • 0001213543 scopus 로고    scopus 로고
    • Regulation of the human inosine monophosphate dehydrogenase type i gene. Utilization of alternative promoters
    • Gu JJ, Spychala J, Mitchell BS. Regulation of the human inosine monophosphate dehydrogenase type I gene. Utilization of alternative promoters. J Biol Chem 1997 272 : 4458 4466.
    • (1997) J Biol Chem , vol.272 , pp. 4458-4466
    • Gu, J.J.1    Spychala, J.2    Mitchell, B.S.3
  • 6
    • 0028967022 scopus 로고
    • Characterization of the human inosine-5′-monophosphate dehydrogenase type II gene
    • Zimmerman AG, Sphycala J, Mitchell BS. Characterization of the human inosine-5′-monophosphate dehydrogenase type II gene. J Biol Chem 1995 270 : 6808 6814.
    • (1995) J Biol Chem , vol.270 , pp. 6808-6814
    • Zimmerman, A.G.1    Sphycala, J.2    Mitchell, B.S.3
  • 7
    • 0034889041 scopus 로고    scopus 로고
    • Adverse gastrointestinal effects of mycophenolate mofetil: Aetiology, incidence and management
    • Behrend M. Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management. Drug Saf 2001 24 : 645 663.
    • (2001) Drug Saf , vol.24 , pp. 645-663
    • Behrend, M.1
  • 8
    • 33846591856 scopus 로고    scopus 로고
    • Noninfectious gastrointestinal (GI) complications of mycophenolic acid therapy: A consequence of local GI toxicity?
    • Arns W. Noninfectious gastrointestinal (GI) complications of mycophenolic acid therapy: a consequence of local GI toxicity? Transplant Proc 2007 39 : 88 93.
    • (2007) Transplant Proc , vol.39 , pp. 88-93
    • Arns, W.1
  • 9
    • 0042536429 scopus 로고    scopus 로고
    • Mycophenolate mofetil dose reduction and the risk of acute rejection after renal transplantation
    • Knoll GA, MacDonald I, Khan A, Van Walraven C. Mycophenolate mofetil dose reduction and the risk of acute rejection after renal transplantation. J Am Soc Nephrol 2003 14 : 2381 2386.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2381-2386
    • Knoll, G.A.1    MacDonald, I.2    Khan, A.3    Van Walraven, C.4
  • 11
    • 27644434992 scopus 로고    scopus 로고
    • The rationale for and limitation of therapeutic drug monitoring for mycophenolate mofetil in transplantation
    • van Gelder T, Shaw LM. The rationale for and limitation of therapeutic drug monitoring for mycophenolate mofetil in transplantation. Transplantation 2005 244 253.
    • (2005) Transplantation , pp. 244-253
    • Van Gelder, T.1    Shaw, L.M.2
  • 15
    • 33846072003 scopus 로고    scopus 로고
    • Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation
    • Kamar N, Glander P, Nolting J, Böhler T, Hambach P, Liefeldt L, Neumayer HH, Klupp J, Budde K. Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation. Transplant Proc 2006 38 : 2292 2294.
    • (2006) Transplant Proc , vol.38 , pp. 2292-2294
    • Kamar, N.1    Glander, P.2    Nolting, J.3    Böhler, T.4    Hambach, P.5    Liefeldt, L.6    Neumayer, H.H.7    Klupp, J.8    Budde, K.9
  • 16
    • 0033047817 scopus 로고    scopus 로고
    • Induction of inosine monophosphate dehydrogenase activity after long-term treatment with mycophenolate mofetil
    • Sanquer S, Breil M, Baron C, Dhamane D, Astier A, Lang P. Induction of inosine monophosphate dehydrogenase activity after long-term treatment with mycophenolate mofetil. Clin Pharmacol Ther 1999 65 : 640 648.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 640-648
    • Sanquer, S.1    Breil, M.2    Baron, C.3    Dhamane, D.4    Astier, A.5    Lang, P.6
  • 17
    • 32344446094 scopus 로고    scopus 로고
    • Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment
    • Vethe NT, Mandla R, Line PD, Midtvedt K, Hartmann A, Bergan S. Inosine monophosphate dehydrogenase activity in renal allograft recipients during mycophenolate treatment. Scand J Clin Lab Invest 2006 66 : 31 44.
    • (2006) Scand J Clin Lab Invest , vol.66 , pp. 31-44
    • Vethe, N.T.1    Mandla, R.2    Line, P.D.3    Midtvedt, K.4    Hartmann, A.5    Bergan, S.6
  • 18
    • 0035100813 scopus 로고    scopus 로고
    • Effect of mycophenolate mofetil therapy on inosine monophosphate dehydrogenase induction in red blood cells of heart transplant recipients
    • Weigel G, Griesmacher A, Zuckermann AO, Laufer G, Mueller MM. Effect of mycophenolate mofetil therapy on inosine monophosphate dehydrogenase induction in red blood cells of heart transplant recipients. Clin Pharmacol Ther 2001 69 : 137 144.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 137-144
    • Weigel, G.1    Griesmacher, A.2    Zuckermann, A.O.3    Laufer, G.4    Mueller, M.M.5
  • 20
    • 3142720312 scopus 로고    scopus 로고
    • Mycophenolate mofetil, an inhibitor of inosine monophosphate dehydrogenase, causes a paradoxical elevation of GTP in erythrocytes of renal transplant patients
    • Goldsmith D, Carrey EA, Edbury S, Smolenski RT, Jagodzinski P, Simmonds HA. Mycophenolate mofetil, an inhibitor of inosine monophosphate dehydrogenase, causes a paradoxical elevation of GTP in erythrocytes of renal transplant patients. Clin Sci 2004 107 : 63 8.
    • (2004) Clin Sci , vol.107 , pp. 63-8
    • Goldsmith, D.1    Carrey, E.A.2    Edbury, S.3    Smolenski, R.T.4    Jagodzinski, P.5    Simmonds, H.A.6
  • 23
    • 0036721306 scopus 로고    scopus 로고
    • Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus
    • Pawinski T, Hale M, Korecka M, Fitzimmons WE, Shaw LM. Limited sampling strategy for the estimation of mycophenolic acid area under the curve in adult renal transplant patients treated with concomitant tacrolimus. Clin Chem 2002 48 : 1497 1504.
    • (2002) Clin Chem , vol.48 , pp. 1497-1504
    • Pawinski, T.1    Hale, M.2    Korecka, M.3    Fitzimmons, W.E.4    Shaw, L.M.5
  • 24
    • 9644281481 scopus 로고    scopus 로고
    • Mycophenolic acid in diabetic renal transplant recipients. Pharmacokinetics and application of a limited sampling strategy
    • van Hest RM, Mathôt RA, Vulto AG, Le Meur Y, van Gelder T. Mycophenolic acid in diabetic renal transplant recipients. Pharmacokinetics and application of a limited sampling strategy. Ther Drug Monit 2004 26 : 620 625.
    • (2004) Ther Drug Monit , vol.26 , pp. 620-625
    • Van Hest, R.M.1    Mathôt, R.A.2    Vulto, A.G.3    Le Meur, Y.4    Van Gelder, T.5
  • 25
    • 38649102165 scopus 로고    scopus 로고
    • Stability of mycophenolic acid and glucuronide metabolites in human plasma and the impact of deproteinization methodology
    • de Loor H, Naesens M, Verbeke K, Vanrenterghem Y, Kuypers DR. Stability of mycophenolic acid and glucuronide metabolites in human plasma and the impact of deproteinization methodology. Clin Chim Acta 2008 389 : 87 92.
    • (2008) Clin Chim Acta , vol.389 , pp. 87-92
    • De Loor, H.1    Naesens, M.2    Verbeke, K.3    Vanrenterghem, Y.4    Kuypers, D.R.5
  • 26
    • 0029058395 scopus 로고
    • Mycophenolic acid binding to human serum albumin: Characterization and relation to pharmacodynamics
    • Nowak I, Shaw LM. Mycophenolic acid binding to human serum albumin: characterization and relation to pharmacodynamics. Clin Chem 1995 41 : 1011 1017.
    • (1995) Clin Chem , vol.41 , pp. 1011-1017
    • Nowak, I.1    Shaw, L.M.2
  • 27
    • 0031804284 scopus 로고    scopus 로고
    • Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography procedure
    • Shipkova M, Niedmann PD, Armstrong VW, Schütz E, Wieland E, Shaw LM, Oellerich M. Simultaneous determination of mycophenolic acid and its glucuronide in human plasma using a simple high-performance liquid chromatography procedure. Clin Chem 1998 44 : 1481 1488.
    • (1998) Clin Chem , vol.44 , pp. 1481-1488
    • Shipkova, M.1    Niedmann, P.D.2    Armstrong, V.W.3    Schütz, E.4    Wieland, E.5    Shaw, L.M.6    Oellerich, M.7
  • 28
    • 8844222031 scopus 로고    scopus 로고
    • Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry
    • Patel CG, Mendonza AE, Akhlaghi F, Majid O, Trull AK, Lee T, Holt DW. Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2004 813 : 287 294.
    • (2004) J Chromatogr B Analyt Technol Biomed Life Sci , vol.813 , pp. 287-294
    • Patel, C.G.1    Mendonza, A.E.2    Akhlaghi, F.3    Majid, O.4    Trull, A.K.5    Lee, T.6    Holt, D.W.7
  • 29
    • 0014387338 scopus 로고
    • Isolation of leucocytes from human blood. A two-phase system for removal of red cells with methylcellulose as erythrocyte-aggregating agent
    • Böyum A. Isolation of leucocytes from human blood. A two-phase system for removal of red cells with methylcellulose as erythrocyte-aggregating agent. Scand J Clin Lab Invest 1968 97 : 9 29.
    • (1968) Scand J Clin Lab Invest , vol.97 , pp. 9-29
    • Böyum, A.1
  • 34
    • 0034120621 scopus 로고    scopus 로고
    • Development and application of a high-performance liquid chromatography-based assay for determination of the activity of inosine 5′-monophosphate dehydrogenase in whole blood and isolated mononuclear cells
    • Albrecht W, Storck M, Pfetsch E, Martin W, Abendroth D. Development and application of a high-performance liquid chromatography-based assay for determination of the activity of inosine 5′-monophosphate dehydrogenase in whole blood and isolated mononuclear cells. Ther Drug Monit 2000 22 : 283 294.
    • (2000) Ther Drug Monit , vol.22 , pp. 283-294
    • Albrecht, W.1    Storck, M.2    Pfetsch, E.3    Martin, W.4    Abendroth, D.5
  • 36
    • 33947602357 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic comparison of enteric-coated mycophenolate sodium and mycophenolate mofetil in maintenance renal transplant patients
    • DOI 10.1111/j.1600-6143.2006.01693.x
    • Budde K, Bauer S, Hambach P, Hahn U, Röblitz H, Mai I, Diekmann F, Neumayer HH, Glander P. Pharmacokinetic and pharmacodynamic comparison of enteric-coated mycophenolate sodium and mycophenolate mofetil in maintenance renal transplant patients. Am J Transplant 2007 7 : 888 898. (Pubitemid 46481185)
    • (2007) American Journal of Transplantation , vol.7 , Issue.4 , pp. 888-898
    • Budde, K.1    Bauer, S.2    Hambach, P.3    Hahn, U.4    Roblitz, H.5    Mai, I.6    Diekmann, F.7    Neumayer, H.-H.8    Glander, P.9
  • 37
    • 0035086852 scopus 로고    scopus 로고
    • Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
    • van Gelder T, Klupp J, Barten MJ, Christians U, Morris RE. Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. Ther Drug Monit 2001 23 : 119 128.
    • (2001) Ther Drug Monit , vol.23 , pp. 119-128
    • Van Gelder, T.1    Klupp, J.2    Barten, M.J.3    Christians, U.4    Morris, R.E.5
  • 38
    • 2442716361 scopus 로고    scopus 로고
    • Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by Mrp2 in rats
    • Kobayashi M, Saitoh H, Kobayashi M, Tadano K, Takahashi Y, Hirano T. Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by Mrp2 in rats. J Pharmacol Exp Ther 2004 309 : 1029 1035.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 1029-1035
    • Kobayashi, M.1    Saitoh, H.2    Kobayashi, M.3    Tadano, K.4    Takahashi, Y.5    Hirano, T.6
  • 39
    • 0038246498 scopus 로고    scopus 로고
    • Mycophenolic acid pharmacodynamic and pharmacokinetics provide a basis for rational monitoring strategies
    • Shaw LM, Korecka M, Venkataramanan R, Golberg L, Bloom R, Brayman KL. Mycophenolic acid pharmacodynamic and pharmacokinetics provide a basis for rational monitoring strategies. Am J Transplant 2003 3 : 534 542.
    • (2003) Am J Transplant , vol.3 , pp. 534-542
    • Shaw, L.M.1    Korecka, M.2    Venkataramanan, R.3    Golberg, L.4    Bloom, R.5    Brayman, K.L.6
  • 41
    • 38349160259 scopus 로고    scopus 로고
    • Expression of inosine monophosphate dehydrogenase type i and type II after mycophenolate mofetil treatment: A 2-year follow-up in kidney transplantation
    • Sanquer S, Maison P, Tomkiewicz C, Macquin-Mavier I, Legendre C, Barouki R, Lang P. Expression of inosine monophosphate dehydrogenase type I and type II after mycophenolate mofetil treatment: a 2-year follow-up in kidney transplantation. Clin Pharmacol Ther 2008 83 : 328 335.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 328-335
    • Sanquer, S.1    Maison, P.2    Tomkiewicz, C.3    MacQuin-Mavier, I.4    Legendre, C.5    Barouki, R.6    Lang, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.