A large human domain antibody library combining heavy and light chain CDR3 diversity

Molecular Immunology

Volumn 47, Issue 4, 2010, Pages 912-921

  Chen, Weizao ^a   Zhu, Zhongyu ^a,b   Feng, Yang ^a   Dimitrov, Dimiter S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

Author keywords

Grafting; Human domain antibody; Library; Light chain CDR3; Phage display

Indexed keywords

ANTIBODY; DOMAIN ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; SCAFFOLD PROTEIN; SOMATOMEDIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIBODY AFFINITY; ANTIBODY LIBRARY; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ARTICLE; COMPLEMENTARITY DETERMINING REGION; COMPLEMENTARITY DETERMINING REGION 3; CONTROLLED STUDY; DRUG SYNTHESIS; ELUTION; FEMALE; FETUS; HEAVY CHAIN; HUMAN; HUMAN CELL; HUMAN TISSUE; LIGHT CHAIN; MALE; MOLECULAR SIZE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIGENS; BASE SEQUENCE; CLONING, MOLECULAR; COMPLEMENTARITY DETERMINING REGIONS; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; STAPHYLOCOCCAL PROTEIN A;

PLEURONECTIDAE;

EID: 72949111167     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.09.039     Document Type: Article

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