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Volumn 83, Issue 24, 2009, Pages 12692-12701

Identification of B-cell epitopes on virus-like particles of cutaneous alpha-human papillomaviruses

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; MONOCLONAL ANTIBODY; WART VIRUS VACCINE;

EID: 72849121998     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01582-09     Document Type: Article
Times cited : (16)

References (58)
  • 1
    • 31144451594 scopus 로고    scopus 로고
    • HPV-associated skin disease
    • Akgul, B., J. C. Cooke, and A. Storey. 2006. HPV-associated skin disease. J. Pathol. 208:165-175.
    • (2006) J. Pathol. , vol.208 , pp. 165-175
    • Akgul, B.1    Cooke, J.C.2    Storey, A.3
  • 2
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 3
    • 33947586116 scopus 로고    scopus 로고
    • Developing an HPV vaccine to prevent cervical cancer and genital warts
    • DOI 10.1016/j.vaccine.2007.01.013, PII S0264410X07000357
    • Bryan, J. T. 2007. Developing an HPV vaccine to prevent cervical cancer and genital warts. Vaccine 25:3001-3006. (Pubitemid 46482731)
    • (2007) Vaccine , vol.25 , Issue.16 SPEC. ISS , pp. 3001-3006
    • Bryan, J.T.1
  • 4
    • 0346688642 scopus 로고    scopus 로고
    • Efficient intracellular assembly of papillomaviral vectors
    • Buck, C. B., D. V. Pastrana, D. R. Lowy, and J. T. Schiller. 2004. Efficient intracellular assembly of papillomaviral vectors. J. Virol. 78:751-757.
    • (2004) J. Virol. , vol.78 , pp. 751-757
    • Buck, C.B.1    Pastrana, D.V.2    Lowy, D.R.3    Schiller, J.T.4
  • 5
    • 70349664875 scopus 로고    scopus 로고
    • Production of papillomavirus-based gene transfer vectors
    • Buck, C. B., and C. D. Thompson. 2007. Production of papillomavirus-based gene transfer vectors. Curr. Protoc. Cell Biol. 37:26.1.1-26.1.19.
    • (2007) Curr. Protoc. Cell Biol. , vol.37
    • Buck, C.B.1    Thompson, C.D.2
  • 7
    • 0142124135 scopus 로고    scopus 로고
    • Identification of a Human Papillomavirus Type 16-Specific Epitope on the C-Terminal Arm of the Major Capsid Protein L1
    • DOI 10.1128/JVI.77.21.11625-11632.2003
    • Carter, J. J., G. C. Wipf, S. F. Benki, N. D. Christensen, and D. A. Galloway. 2003. Identification of a human papillomavirus type 16-specific epitope on the C-terminal arm of the major capsid protein L1. J. Virol. 77:11625-11632. (Pubitemid 37271661)
    • (2003) Journal of Virology , vol.77 , Issue.21 , pp. 11625-11632
    • Carter, J.J.1    Wipf, G.C.2    Benki, S.F.3    Christensen, N.D.4    Galloway, D.A.5
  • 8
    • 34548677936 scopus 로고    scopus 로고
    • A prospective pilot study of antibodies against human papillomaviruses and cutaneous squamous cell carcinoma nested in the Oxford component of the European Prospective Investigation into Cancer and Nutrition
    • Casabonne, D., K. M. Michael, T. Waterboer, M. Pawlita, O. Forslund, R. D. Burk, R. C. Travis, T. J. Key, and R. Newton. 2007. A prospective pilot study of antibodies against human papillomaviruses and cutaneous squamous cell carcinoma nested in the Oxford component of the European Prospective Investigation into Cancer and Nutrition. Int. J. Cancer 121:1862-1868.
    • (2007) Int. J. Cancer , vol.121 , pp. 1862-1868
    • Casabonne, D.1    Michael, K.M.2    Waterboer, T.3    Pawlita, M.4    Forslund, O.5    Burk, R.D.6    Travis, R.C.7    Key, T.J.8    Newton, R.9
  • 9
    • 0031583860 scopus 로고    scopus 로고
    • Phylogenetic analysis of the human papillomavirus type 2 (HPV-2), HPV-27, and HPV-57 group, which is associated with common warts
    • Chan, S. Y., S. H. Chew, K. Egawa, E. I. Grussendorf-Conen, Y. Honda, A. Rubben, K. C. Tan, and H. U. Bernard. 1997. Phylogenetic analysis of the human papillomavirus type 2 (HPV-2), HPV-27, and HPV-57 group, which is associated with common warts. Virology 239:296-302.
    • (1997) Virology , vol.239 , pp. 296-302
    • Chan, S.Y.1    Chew, S.H.2    Egawa, K.3    Grussendorf-Conen, E.I.4    Honda, Y.5    Rubben, A.6    Tan, K.C.7    Bernard, H.U.8
  • 10
    • 0035896012 scopus 로고    scopus 로고
    • Papillomavirus capsid protein expression in Escherichia coli: Purification and assembly of HPV11 and HPV16 L1
    • Chen, X. S., G. Casini, S. C. Harrison, and R. L. Garcea. 2001. Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1. J. Mol. Biol. 307:173-182.
    • (2001) J. Mol. Biol. , vol.307 , pp. 173-182
    • Chen, X.S.1    Casini, G.2    Harrison, S.C.3    Garcea, R.L.4
  • 11
    • 0033696899 scopus 로고    scopus 로고
    • Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16
    • Chen, X. S., R. L. Garcea, I. Goldberg, G. Casini, and S. C. Harrison. 2000. Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16. Mol. Cell 5:557-567. (Pubitemid 30950045)
    • (2000) Molecular Cell , vol.5 , Issue.3 , pp. 557-567
    • Chen, X.S.1    Garcea, R.L.2    Goldberg, I.3    Casini, G.4    Harrison, S.C.5
  • 12
    • 0035694879 scopus 로고    scopus 로고
    • Hybrid papillomavirus L1 molecules assemble into virus-like particles that reconstitute conformational epitopes and induce neutralizing antibodies to distinct HPV types
    • Christensen, N. D., N. M. Cladel, C. A. Reed, L. R. Budgeon, M. E. Embers, D. M. Skulsky, W. L. McClements, S. W. Ludmerer, and K. U. Jansen. 2001. Hybrid papillomavirus L1 molecules assemble into virus-like particles that reconstitute conformational epitopes and induce neutralizing antibodies to distinct HPV types. Virology 291:324-334.
    • (2001) Virology , vol.291 , pp. 324-334
    • Christensen, N.D.1    Cladel, N.M.2    Reed, C.A.3    Budgeon, L.R.4    Embers, M.E.5    Skulsky, D.M.6    McClements, W.L.7    Ludmerer, S.W.8    Jansen, K.U.9
  • 13
    • 0030245737 scopus 로고    scopus 로고
    • Surface conformational and linear epitopes on HPV-16 and HPV-18 L1 virus-like particles as defined by monoclonal antibodies
    • Christensen, N. D., J. Dillner, C. Eklund, J. J. Carter, G. C. Wipf, C. A. Reed, N. M. Cladel, and D. A. Galloway. 1996. Surface conformational and linear epitopes on HPV-16 and HPV-18 L1 virus-like particles as defined by monoclonal antibodies. Virology 223:174-184.
    • (1996) Virology , vol.223 , pp. 174-184
    • Christensen, N.D.1    Dillner, J.2    Eklund, C.3    Carter, J.J.4    Wipf, G.C.5    Reed, C.A.6    Cladel, N.M.7    Galloway, D.A.8
  • 14
    • 0027930718 scopus 로고
    • Assembled baculovirus-expressed human papillomavirus type 11 L1 capsid protein viruslike particles are recognized by neutralizing monoclonal antibodies and induce high titres of neutralizing antibodies
    • Christensen, N. D., R. Hopfl, S. L. DiAngelo, N. M. Cladel, S. D. Patrick, P. A. Welsh, L. R. Budgeon, C. A. Reed, and J. W. Kreider. 1994. Assembled baculovirus-expressed human papillomavirus type 11 L1 capsid protein viruslike particles are recognized by neutralizing monoclonal antibodies and induce high titres of neutralizing antibodies. J. Gen. Virol. 75(Pt. 9):2271-2276.
    • (1994) J. Gen. Virol. , vol.75 , Issue.PART 9 , pp. 2271-2276
    • Christensen, N.D.1    Hopfl, R.2    DiAngelo, S.L.3    Cladel, N.M.4    Patrick, S.D.5    Welsh, P.A.6    Budgeon, L.R.7    Reed, C.A.8    Kreider, J.W.9
  • 15
    • 0028080322 scopus 로고
    • Human papillomavirus types 6 and 11 have antigenically distinct strongly immunogenic conformationally dependent neutralizing epitopes
    • Christensen, N. D., R. Kirnbauer, J. T. Schiller, S. J. Ghim, R. Schlegel, A. B. Jenson, and J. W. Kreider. 1994. Human papillomavirus types 6 and 11 have antigenically distinct strongly immunogenic conformationally dependent neutralizing epitopes. Virology 205:329-335.
    • (1994) Virology , vol.205 , pp. 329-335
    • Christensen, N.D.1    Kirnbauer, R.2    Schiller, J.T.3    Ghim, S.J.4    Schlegel, R.5    Jenson, A.B.6    Kreider, J.W.7
  • 16
    • 0025008146 scopus 로고
    • Monoclonal antibody-mediated neutralization of infectious human papillomavirus type 11
    • Christensen, N. D., J. W. Kreider, N. M. Cladel, S. D. Patrick, and P. A. Welsh. 1990. Monoclonal antibody-mediated neutralization of infectious human papillomavirus type 11. J. Virol. 64:5678-5681. (Pubitemid 20364570)
    • (1990) Journal of Virology , vol.64 , Issue.11 , pp. 5678-5681
    • Christensen, N.D.1    Kreider, J.W.2    Cladel, N.M.3    Patrick, S.D.4    Welsh, P.A.5
  • 17
    • 0030588285 scopus 로고    scopus 로고
    • Monoclonal antibodies to HPV-6 L1 virus-like particles identify conformational and linear neutralizing epitopes on HPV-11 in addition to typespecific epitopes on HPV-6
    • Christensen, N. D., C. A. Reed, N. M. Cladel, K. Hall, and G. S. Leiserowitz. 1996. Monoclonal antibodies to HPV-6 L1 virus-like particles identify conformational and linear neutralizing epitopes on HPV-11 in addition to typespecific epitopes on HPV-6. Virology 224:477-486.
    • (1996) Virology , vol.224 , pp. 477-486
    • Christensen, N.D.1    Reed, C.A.2    Cladel, N.M.3    Hall, K.4    Leiserowitz, G.S.5
  • 18
    • 0042345044 scopus 로고    scopus 로고
    • Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: A meta-analysis
    • DOI 10.1038/sj.bjc.6601024
    • Clifford, G. M., J. S. Smith, T. Aguado, and S. Franceschi. 2003. Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: a meta-analysis. Br. J. Cancer 89:101-105. (Pubitemid 36897943)
    • (2003) British Journal of Cancer , vol.89 , Issue.1 , pp. 101-105
    • Clifford, G.M.1    Smith, J.S.2    Aguado, T.3    Franceschi, S.4
  • 19
    • 0036284220 scopus 로고    scopus 로고
    • Identification of two cross-neutralizing linear epitopes within the L1 major capsid protein of human papillomaviruses
    • Combita, A. L., A. Touze, L. Bousarghin, N. D. Christensen, and P. Coursaget. 2002. Identification of two cross-neutralizing linear epitopes within the L1 major capsid protein of human papillomaviruses. J. Virol. 76:6480-6486.
    • (2002) J. Virol. , vol.76 , pp. 6480-6486
    • Combita, A.L.1    Touze, A.2    Bousarghin, L.3    Christensen, N.D.4    Coursaget, P.5
  • 24
    • 33646058566 scopus 로고    scopus 로고
    • Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: Follow-up from a randomised control trial
    • Harper, D. M., E. L. Franco, C. M. Wheeler, A. B. Moscicki, B. Romanowski, C. M. Roteli-Martins, D. Jenkins, A. Schuind, S. A. Costa Clemens, and G. Dubin. 2006. Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial. Lancet 367:1247-1255.
    • (2006) Lancet , vol.367 , pp. 1247-1255
    • Harper, D.M.1    Franco, E.L.2    Wheeler, C.M.3    Moscicki, A.B.4    Romanowski, B.5    Roteli-Martins, C.M.6    Jenkins, D.7    Schuind, A.8    Costa Clemens, S.A.9    Dubin, G.10
  • 25
    • 0036208342 scopus 로고    scopus 로고
    • Human papillomaviruses and nonmelanoma skin cancer
    • Harwood, C. A., and C. M. Proby. 2002. Human papillomaviruses and nonmelanoma skin cancer. Curr. Opin. Infect. Dis. 15:101-114.
    • (2002) Curr. Opin. Infect. Dis. , vol.15 , pp. 101-114
    • Harwood, C.A.1    Proby, C.M.2
  • 27
    • 0027050013 scopus 로고
    • Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic
    • Kirnbauer, R., F. Booy, N. Cheng, D. R. Lowy, and J. T. Schiller. 1992. Papillomavirus L1 major capsid protein self-assembles into virus-like particles that are highly immunogenic. Proc. Natl. Acad. Sci. USA 89:12180-12184.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 12180-12184
    • Kirnbauer, R.1    Booy, F.2    Cheng, N.3    Lowy, D.R.4    Schiller, J.T.5
  • 28
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler, G., and C. Milstein. 1975. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256:495-497.
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 29
    • 0028899667 scopus 로고
    • Cutaneous warts and tumours in immunosuppressed patients
    • Leigh, I. M., and M. T. Glover. 1995. Cutaneous warts and tumours in immunosuppressed patients. J. R. Soc. Med. 88:61-62.
    • (1995) J. R. Soc. Med. , vol.88 , pp. 61-62
    • Leigh, I.M.1    Glover, M.T.2
  • 30
    • 0031936604 scopus 로고    scopus 로고
    • Intercapsomeric disulfide bonds in papillomavirus assembly and disassembly
    • Li, M., P. Beard, P. A. Estes, M. K. Lyon, and R. L. Garcea. 1998. Intercapsomeric disulfide bonds in papillomavirus assembly and disassembly. J. Virol. 72:2160-2167. (Pubitemid 28100772)
    • (1998) Journal of Virology , vol.72 , Issue.3 , pp. 2160-2167
    • Li, M.1    Beard, P.2    Estes, P.A.3    Lyon, M.K.4    Garcea, R.L.5
  • 31
    • 0029941003 scopus 로고    scopus 로고
    • Two amino acid residues confer type specificity to a neutralizing, conformationally dependent epitope on human papillomavirus type 11
    • Ludmerer, S. W., D. Benincasa, and G. E. Mark III. 1996. Two amino acid residues confer type specificity to a neutralizing, conformationally dependent epitope on human papillomavirus type 11. J. Virol. 70:4791-4794.
    • (1996) J. Virol. , vol.70 , pp. 4791-4794
    • Ludmerer, S.W.1    Benincasa, D.2    Mark III, G.E.3
  • 32
    • 0030896195 scopus 로고    scopus 로고
    • A neutralizing epitope of human papillomavirus type 11 is principally described by a continuous set of residues which overlap a distinct linear, surface-exposed epitope
    • Ludmerer, S. W., D. Benincasa, G. E. Mark III, and N. D. Christensen. 1997. A neutralizing epitope of human papillomavirus type 11 is principally described by a continuous set of residues which overlap a distinct linear, surface-exposed epitope. J. Virol. 71:3834-3839.
    • (1997) J. Virol. , vol.71 , pp. 3834-3839
    • Ludmerer, S.W.1    Benincasa, D.2    Mark III, G.E.3    Christensen, N.D.4
  • 33
    • 0034688151 scopus 로고    scopus 로고
    • HPV11 mutant virus-like particles elicit immune responses that neutralize virus and delineate a novel neutralizing domain
    • Ludmerer, S. W., W. L. McClements, X. M. Wang, J. C. Ling, K. U. Jansen, and N. D. Christensen. 2000. HPV11 mutant virus-like particles elicit immune responses that neutralize virus and delineate a novel neutralizing domain. Virology 266:237-245.
    • (2000) Virology , vol.266 , pp. 237-245
    • Ludmerer, S.W.1    McClements, W.L.2    Wang, X.M.3    Ling, J.C.4    Jansen, K.U.5    Christensen, N.D.6
  • 34
    • 0023091932 scopus 로고
    • Baculovirus expression vectors: The requirements for high level expression of proteins, including glycoproteins
    • Matsuura, Y., R. D. Possee, H. A. Overton, and D. H. Bishop. 1987. Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins. J. Gen. Virol. 68(Pt. 5):1233-1250.
    • (1987) J. Gen. Virol. , vol.68 , Issue.PART 5 , pp. 1233-1250
    • Matsuura, Y.1    Possee, R.D.2    Overton, H.A.3    Bishop, D.H.4
  • 35
    • 0035950614 scopus 로고    scopus 로고
    • A novel human papillomavirus type 6 neutralizing domain comprising two discrete regions of the major capsid protein L1
    • McClements, W. L., X. M. Wang, J. C. Ling, D. M. Skulsky, N. D. Christensen, K. U. Jansen, and S. W. Ludmerer. 2001. A novel human papillomavirus type 6 neutralizing domain comprising two discrete regions of the major capsid protein L1. Virology 289:262-268.
    • (2001) Virology , vol.289 , pp. 262-268
    • McClements, W.L.1    Wang, X.M.2    Ling, J.C.3    Skulsky, D.M.4    Christensen, N.D.5    Jansen, K.U.6    Ludmerer, S.W.7
  • 37
    • 0023605321 scopus 로고
    • A comparison of spleen and lymph node cells as fusion partners for the raising of mono-clonal antibodies after different routes of immunisation
    • Mirza, I. H., T. J. Wilkin, M. Cantarini, and K. Moore. 1987. A comparison of spleen and lymph node cells as fusion partners for the raising of mono-clonal antibodies after different routes of immunisation. J. Immunol. Methods 105:235-243.
    • (1987) J. Immunol. Methods , vol.105 , pp. 235-243
    • Mirza, I.H.1    Wilkin, T.J.2    Cantarini, M.3    Moore, K.4
  • 44
    • 33748334303 scopus 로고    scopus 로고
    • Codon optimized expression of HPV 16 E6 renders target cells susceptible to E6-specific CTL recognition
    • Samorski, R., L. Gissmann, and W. Osen. 2006. Codon optimized expression of HPV 16 E6 renders target cells susceptible to E6-specific CTL recognition. Immunol. Lett. 107:41-49.
    • (2006) Immunol. Lett. , vol.107 , pp. 41-49
    • Samorski, R.1    Gissmann, L.2    Osen, W.3
  • 45
    • 0031777693 scopus 로고    scopus 로고
    • Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines
    • Sapp, M., C. Fligge, I. Petzak, J. R. Harris, and R. E. Streeck. 1998. Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines. J. Virol. 72:6186-6189. (Pubitemid 28283413)
    • (1998) Journal of Virology , vol.72 , Issue.7 , pp. 6186-6189
    • Sapp, M.1    Fligge, C.2    Petzak, I.3    Harris, J.R.4    Streeck, R.E.5
  • 46
    • 0015641518 scopus 로고
    • Denaturation of lysozyme by Freund's complete adjuvant
    • Scibienski, R. J. 1973. Denaturation of lysozyme by Freund's complete adjuvant. J. Immunol. 111:114-120.
    • (1973) J. Immunol. , vol.111 , pp. 114-120
    • Scibienski, R.J.1
  • 47
    • 0036805546 scopus 로고    scopus 로고
    • HPV antibody detection by ELISA with capsid protein L1 fused to glutathione S-transferase
    • DOI 10.1016/S0166-0934(02)00134-9, PII S0166093402001349
    • Sehr, P., M. Muller, R. Hopfl, A. Widschwendter, and M. Pawlita. 2002. HPV antibody detection by ELISA with capsid protein L1 fused to glutathione S-transferase. J. Virol. Methods 106:61-70. (Pubitemid 35279650)
    • (2002) Journal of Virological Methods , vol.106 , Issue.1 , pp. 61-70
    • Sehr, P.1    Muller, M.2    Hopfl, R.3    Widschwendter, A.4    Pawlita, M.5
  • 48
    • 0035400487 scopus 로고    scopus 로고
    • A generic capture ELISA for recombinant proteins fused to glutathione S-transferase: Validation for HPV serology
    • DOI 10.1016/S0022-1759(01)00376-3, PII S0022175901003763
    • Sehr, P., K. Zumbach, and M. Pawlita. 2001. A generic capture ELISA for recombinant proteins fused to glutathione S-transferase: validation for HPV serology. J. Immunol. Methods 253:153-162. (Pubitemid 32522523)
    • (2001) Journal of Immunological Methods , vol.253 , Issue.1-2 , pp. 153-162
    • Sehr, P.1    Zumbach, K.2    Pawlita, M.3
  • 49
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper, C. M., and W. E. Paul. 1987. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944-947.
    • (1987) Science , vol.236 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 51
    • 14044250981 scopus 로고    scopus 로고
    • Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo
    • Tannous, B. A., D. E. Kim, J. L. Fernandez, R. Weissleder, and X. O. Breakefield. 2005. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol. Ther. 11:435-443.
    • (2005) Mol. Ther. , vol.11 , pp. 435-443
    • Tannous, B.A.1    Kim, D.E.2    Fernandez, J.L.3    Weissleder, R.4    Breakefield, X.O.5
  • 52
    • 43949083734 scopus 로고    scopus 로고
    • A direct comparison of human papillomavirus type 16 L1 particles reveals a lower immunogenicity of capsomeres than viruslike particles with respect to the induced antibody response
    • DOI 10.1128/JVI.02482-07
    • Thönes, N., A. Herreiner, L. Schädlich, K. Piuko, and M. Müller. 2008. A direct comparison of human papillomavirus type 16 L1 particles reveals a lower immunogenicity of capsomeres than viruslike particles with respect to the induced antibody response. J. Virol. 82:5472-5485. (Pubitemid 351705254)
    • (2008) Journal of Virology , vol.82 , Issue.11 , pp. 5472-5485
    • Thones, N.1    Herreiner, A.2    Schadlich, L.3    Piuko, K.4    Muller, M.5
  • 55
    • 31944441629 scopus 로고    scopus 로고
    • Suppression of non-specific binding in serological Luminex assays
    • DOI 10.1016/j.jim.2005.11.008, PII S0022175905004023
    • Waterboer, T., P. Sehr, and M. Pawlita. 2006. Suppression of non-specific binding in serological Luminex assays. J. Immunol. Methods 309:200-204. (Pubitemid 43190816)
    • (2006) Journal of Immunological Methods , vol.309 , Issue.1-2 , pp. 200-204
    • Waterboer, T.1    Sehr, P.2    Pawlita, M.3


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