Monoclonal antibodies to HPV-6 L1 virus-like particles identify conformational and linear neutralizing epitopes on HPV-11 in addition to type-specific epitopes on HPV-6

Virology

Volumn 224, Issue 2, 1996, Pages 477-486

  Christensen, Neil D ^a   Reed, Cynthia A ^a   Cladel, Nancy M ^a   Hall, Kathleen ^b   Leiserowitz, Gary S ^b  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; NONHUMAN; PAPILLOMA VIRUS; PRIORITY JOURNAL; VIRUS NEUTRALIZATION; VIRUS PARTICLE;

PAPILLOMAVIRUS;

EID: 0030588285     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.0554     Document Type: Article

References (40)

1. Berzofsky, J. A. (1985). Intrinsic and extrinsic factors in protein antigenic structure. Science 229, 932-940.
2. Breitburd, F., Kirnbauer, R., Hubbert, N. L., Nonnenmacher, B., TrinDinh-Desmarquet, C., Orth, G., Schiller, J. T., and Lowy, D. R. (1995). Immunization with viruslike particles from cottontail rabbit papillomavirus (CRPV) can protect against experimental CRPV infection. J. Virol. 69, 3959-3963.
3. Chandrachud, L. M., Grindlay, G. J., McGarvie, G. M., O'Neil, B. W., Wagner, E. R., Jarrett, W. F. H., and Campo, M. S. (1995). Vaccination of cattle with the N-terminus of L2 is necessary and sufficient for preventing infection by bovine papillomavirus-4. Virology 211, 204-208.
4. Christensen, N. D., Kreider, J. W., Cladel, N. M., Patrick, S. D., and Welsh, P. A. (1990). Monoclonal antibody-mediated neutralization of infectious human papillomavirus type 11. J. Virol. 64, 5678-5681.
5. Christensen, N. D., Kreider, J. W., Kan, N. C., and DiAngelo, S. L. (1991). The open reading frame L2 of cottontail rabbit papillomavirus contains antibody-inducing neutralizing epitopes. Virology 181, 572-579.
6. Christensen, N. D., Kirnbauer, R., Schiller, J. T., Ghim, S.-J., Schlegel, R., and Kreider, J. W. (1994). Human papillomavirus types 6 and 11 have antigenically distinct strongly immunogenic conformationally dependent neutralizing epitopes. Virology 205, 329-335.
7. Christensen, N. D., Reed, C. A., and Cladel, N. M. (1995). Induction of neutralizing antibodies to papillomaviruses by anti-idiotypic antibodies. Virology 210, 292-301.
8. Christensen, N. D., Dillner, J., Eklund, C., Carter, J. J., Wipf, G. C., Reed, C. A., Cladel, N. M., and Galloway, D. A. (1996). Surface conformational and linear epitopes on HPV-16 and HPV-18 L1 virus-like particles as defined by monoclonal antibodies. Virology, in press.
9. Christensen, N. D., and Kreider, J. W. (1991). Neutralization of CRPV infectivity by monoclonal antibodies that identify conformational epitopes on intact virions. Virus Res. 21, 169-179.
10. Christensen, N. D., and Kreider, J. W. (1993). Monoclonal antibody neutralization of BPV-1. Virus Res. 28, 195-202.
11. Clegg, J. C. S., Chanas, A. C., and Gould, E. A. (1983). Conformational changes in sindbis virus E1 glycoprotein induced by monoclonal antibody binding. J. Gen. Virol. 64, 1121-1126.
12. Cowsert, L. M., Lake, P., and Jenson, A. B. (1987). Topographical and conformational epitopes of bovine papillomavirus type 1 defined by monoclonal antibodies. J. Natl. Cancer Inst. 79, 1053-1058.
13. Dean, J., and Schechter, A. N. (1979). Conformation-specific antibodies to the a-chain COOH terminus of hemoglobin Ao. J. Biol. Chem. 254, 9185-9193.
14. Favre, M., Breitburd, F., Croissant, O., and Orth, G. (1975). Structural polypeptides of rabbit, bovine and human papillomaviruses. J. Virol. 15, 1239-1247.
15. Galfre, G., Howe, S. C., Milstein, C., Butcher, G. W., and Howard, J. C. (1977). Antibodies to major histocompatibility antigens produced by hybrid cell lines. Nature 266, 550-552.
16. Ghim, S., Christensen, N. D., Kreider, J. W., and Jensen, A. B. (1991). Comparison of neutralization of BPV-1 infection of C127 cells and bovine fetal skin xenografts. Int. J. Cancer 49, 285-289.
17. Hines, J. R., Ghim, S. J., Christensen, N. D., Kreider, J. W., Barnes, W. A., Schlegel, R., and Jenson, A. B. (1995). The expressed L1 proteins of HPV-1, HPV-6 and HPV-11 display type-specific epitopes with native conformation and reactivity with neutralizing and nonneutralizing antibodies. Pathobiology 62, 165-170.
18. Iverson, B. L., and Lerner, R. A. (1989). Sequence-specific peptide cleavage catalyzed by an antibody. Science 243, 1184-1188.
19. Jarrett, W. F. H., O'Neil, B. W., Gaukroger, J. M., Smith, K. T., Laird, H. M., and Campo, M. S. (1990). Studies on vaccination against papillomaviruses: The immunity after infection and vaccination with bovine papillomaviruses of different types. Vet. Rec. 126, 473-475.
20. Jenison, S. A., Firzlaff, J. M., Langenberg, A., and Galloway, D. A. (1988). Identification of immunoreactive antigens of human papillomavirus type 6b by using Escherichia coli-expressed fusion proteins. J. Virol. 62, 2115-2123.
21. Jenson, A. B., Rosenthal, J. D., Olson, C., Pass, F., Lancaster, W. D., and Shah, K. V. (1980). Immunologic relatedness of papillomaviruses from different species. J. Natl. Cancer Inst. 64, 495-500.
22. Kirnbauer, R., Booy, F., Cheng, N., Lowry, D. R., and Schiller, J. T. (1992). Papillomavirus L1 major capsid protein self-assembles into viruslike particles that are highly immunogenic. Proc. Natl. Acad. Sci. USA 89, 12180-12184.
23. Kreider, J. W., Howett, M. K., Wolfe, S. A., Bartlett, G. L., Zaino, R. J., Sedlacek, T. V., and Mortel, R. (1985). Morphological transformation in vivo of human uterine cervix with papillomavirus from condylomata acuminata. Nature 317, 639-641.
24. Lin, Y.-L., Borenstein, L. A., Selvakumar, R., Ahmed, R., and Wettstein, F. O. (1992). Effective vaccination against papilloma development by immunization with L1 or L2 structural protein of cottontail rabbit papillomavirus. Virology 187, 612-619.
25. Lin, Y.-L., Borenstein, L. A., Ahmed, R., and Wettstein, F. O. (1993). Cottontail rabbit papillomavirus L1 protein-based vaccines: Protection is achieved only with a full-length, nondenatured product. J. Virol. 67, 4154-4162.
26. Ludmerer, S. W., Benincasa, D., and Mark, G. E., III (1996). Two amino acid residues confer type-specificity to a neutralizing, conformationally dependent epitope on human papillomavirus type 11. J. Virol. 70, 4791-4794.
27. McCullough, K. C., Smale, C. J., Carpenter, W. C., Crowther, J. R., Brocchi, E., and De Simone, F. (1987). Conformational alteration in foot-and-mouth disease virus virion capsid structure after complexing with monospecific antibody. Immunology 60, 75-82.
28. Monod, J., Wyman, J., and Changeux, J.-P. (1965). On the nature of allosteric transitions: A plausible model. J. Mol. Biol. 12, 88-118.
29. Müller, M., Gissmann, L., Cristiano, R. J., Sun, X.-Y., Frazer, I. H., Jenson, A. B., Alonso, A., Zentgraf, H., and Zhou, J. (1995). Papillomavirus capsid binding and uptake by cells from different tissues and species. J. Virol. 69, 948-954.
30. Pilacinski, W. P., Glassman, D. L., Krzyzek, R. A., Sadowski, P. L., and Robbins, A. K. (1984). Cloning and expression in Escherichia coli of the bovine papillomavirus L1 and L2 open reading frames. BioTechniques 2, 356-360.
31. Rini, J. M., Schulze-Gahmen, U., and Wilson, I. A. (1992). Structural evidence for induced fit as a mechanism for antibody-antigen recognition. Science 255, 959-965.
32. Roden, R. B. S., Kirnbauer, R., Jenson, A. B., Lowry, D. R., and Schiller, J. T. (1994a). Interaction of papillomaviruses with the cell surface. J. Virol. 68, 7260-7266.
33. Roden, R. B. S., Weissinger, E. M., Henderson, D. W., Booy, F., Kirnbauer, R., Mushinski, J. F., Lowry, D. R., and Schiller, J. T. (1994b). Neutralization of bovine papillomavirus by antibodies to L1 and L2 capsid proteins. J. Virol. 68, 7570-7574.
34. Roden, R. B. S., Hubbert, N. L., Kirnbauer, R., Breitburd, F., Lowy, D. R., and Schiller, J. T. (1995). Papillomavirus L1 capsids agglutinate mouse erythrocytes through a proteinaceous receptor. J. Virol. 69, 5147-5151.
35. Roden, R. B. S., Hubbert, N. L., Kirnbauer, R., Christensen, N. D., Lowy, D. R., and Schiller, J. T. (1996). Assessment of the serological relatedness of genital human papillomaviruses by hemagglutination inhibition. J. Virol. 70, 3298-3301.
36. Rose, R. C., Bonnez, W., Da Rin, C., McCance, D. J., and Reichman, R. C. (1994). Serological differentiation of human papillomavirus types 11, 16 and 18 using recombinant virus-like particles. J. Gen. Virol. 75, 2445-2449.
37. Smith, L. H., Foster, C., Hitchcock, M. E., and Isseroff, R. (1993). In vitro HPV-11 infection of human foreskin. J. Invest. Dermatol. 101, 292-295.
38. Smith, L. H., Foster, C., Hitchcock, M. E., Leiserowitz, G. S., Hall, K., Isseroff, R., Christensen, N. D., and Kreider, J. W. (1995). Titration of HPV-11 infectivity and antibody neutralization can be measured in vitro. J. Invest. Dermatol. 105, 438-444.
39. Stanfield, R. L., Fieser, T. M., Lerner, R. A., and Wilson, I. A. (1990). Crystal structures of an antibody to a peptide and its complex with peptide at 2.8 A. Science 248, 712-719.
40. Volpers, C., Unckell, F., Schirmacher, P., Streeck, R. E., and Sapp, M. (1995). Binding and internalization of human papillomavirus type 33 virus-like particles by eukaryotic cells. J. Virol. 69, 3258-3264.