Single-molecule analysis of the human telomerase RNA·dyskerin interaction and the effect of dyskeratosis congenita mutations

Biochemistry

Volumn 48, Issue 46, 2009, Pages 10858-10865

  Ashbridge, Beth ^a   Orte, Angel ^a,d   Yeoman, Justin A ^a,e   Kirwan, Michael ^c   Vulliamy, Tom ^c   Dokal, Inderjeet ^c   Klenerman, David ^a   Balasubramanian, Shankar ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF GRANADA   (Spain)

^e UNIVERSITY OF AGRICULTURAL SCIENCES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL DOMINANTS; BIOPHYSICAL ANALYSIS; CLINICAL GENETICS; COINCIDENCE DETECTION; DIRECT INTERACTIONS; HUMAN TELOMERASE; RESEARCH PROBLEMS; SINGLE-MOLECULE; SINGLE-MOLECULE ANALYSIS; SUB-DOMAINS; TELOMERASE; TWO-COLOR;

COINCIDENCE CIRCUITS; RNA;

NUCLEIC ACIDS;

DYSKERIN; MUTANT PROTEIN; RNA; TELOMERASE;

ARTICLE; CONTROLLED STUDY; DYSKERATOSIS CONGENITA; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN RNA BINDING; RNA ANALYSIS;

AMINO ACID SUBSTITUTION; BINDING SITES; CELL CYCLE PROTEINS; CELL LINE; DNA RESTRICTION ENZYMES; DYSKERATOSIS CONGENITA; HUMANS; MICROSCOPY, CONFOCAL; MUTATION; NUCLEAR PROTEINS; POINT MUTATION; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; RNA; SIGNAL PROCESSING, COMPUTER-ASSISTED; SPECTROMETRY, FLUORESCENCE; TELOMERASE; TRANSFECTION;

EID: 72749119233     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901373e     Document Type: Article

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