Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP®) for the treatment of viper envenoming in sub-Saharan Africa

Toxicon

Volumn 55, Issue 2-3, 2010, Pages 369-374

  Segura, Álvaro ^a   Villalta, Mauren ^a   Herrera, María ^a   León, Guillermo ^a   Harrison, Robert ^b   Durfa, Nandul ^c   Nasidi, Abdusalami ^c   Calvete, Juan J ^d   Theakston, R David G ^b   Warrell, David A ^b,e   Gutiérrez, José María ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^c Federal Ministry of Health   (Nigeria)

^d INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Antivenom; Bitis sp; Coagulant activity; Echis sp; Hemorrhage; Lethality; Snake venoms; Snakebite; sub Saharan Africa

Indexed keywords

ECHITAB PLUS ICP; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG; VIPER VENOM;

AFRICA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD CLOTTING; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; ENVENOMATION; HORSE; IMMUNIZATION; LETHALITY; MOUSE; NECROSIS; NIGERIA; NONHUMAN; PRIORITY JOURNAL; SERODIAGNOSIS; SNAKE; TOXICITY;

AFRICA; ANIMALS; ANTIVENINS; BLOOD COAGULATION; HEMORRHAGE; INJECTIONS, INTRAVENOUS; LETHAL DOSE 50; MICE; NECROSIS; NEUTRALIZATION TESTS; SKIN; SNAKE BITES; SUBSTRATE SPECIFICITY; VIPER VENOMS; VIPERIDAE;

BITIS; BITIS ARIETANS; BITIS GABONICA; BITIS NASICORNIS; BITIS RHINOCEROS; ECHIS; ECHIS LEUCOGASTER; ECHIS OCELLATUS; ECHIS PYRAMIDUM LEAKEYI; EQUIDAE; NAJA NIGRICOLLIS; VIPERIDAE; VIPERINAE;

EID: 72749113534     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2009.08.010     Document Type: Article

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