Unscrupulous marketing of snake bite antivenoms in Africa and Papua New Guinea: choosing the right product-'What's in a name?'

Transactions of the Royal Society of Tropical Medicine and Hygiene

Volumn 102, Issue 5, 2008, Pages 397-399

  Warrell, David A ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Antivenom; Echis ocellatus; Oxyuranus scutellatus canni; Papua New Guinea; Snake bite; Snake taxonomy; West Africa

Indexed keywords

FAV AFRIQUE; SNAKE VENOM ANTISERUM; UNCLASSIFIED DRUG;

AFRICA; ARTICLE; ASIA; CONFUSION; DRUG LABELING; DRUG MANUFACTURE; DRUG MARKETING; DRUG MISUSE; DRUG SAFETY; ENVENOMATION; FATALITY; HEALTH CARE AVAILABILITY; HEALTH CARE DELIVERY; HUMAN; INDIA; MEDICAL DECISION MAKING; PAPUA NEW GUINEA; QUALITY CONTROL; SNAKE; SNAKEBITE; SPECIES DIFFERENCE;

AFRICA; ANIMALS; ANTIVENINS; BLOOD COAGULATION FACTORS; DRUG EVALUATION, PRECLINICAL; DRUG INDUSTRY; HEMORRHAGE; HEMOSTASIS; HUMANS; IMMUNOLOGIC FACTORS; MARKETING; PAPUA NEW GUINEA; RURAL HEALTH; SNAKE BITES; SPECIES SPECIFICITY; VIPER VENOMS; VIPERIDAE;

ECHIS OCELLATUS; ECHIS PYRAMIDUM; OXYURANUS SCUTELLATUS CANNI; SERPENTES;

EID: 41749101463     PISSN: 00359203     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trstmh.2007.12.005     Document Type: Article

References (23)

1. Chippaux J.P. Ophidian envenomations and emergencies in sub-Saharan Africa. Bull. Soc. Pathol. Exot. 98 (2005) 263-268 [in French]
2. 2 polyvalent equine antivenom for African snake bites in Benin. Am. J. Trop. Med. Hyg. 77 (2007) 538-546
3. Gutiérrez J.M., Rojas E., Quesada L., León G., Núñez J., Laing G.D., Sasa M., Renjifo J.M., Nasidi A., Warrell D.A., Theakston R.D., and Rojas G. Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa. Trans. R. Soc. Trop. Med. Hyg. 99 (2005) 468-475
4. Gutiérrez J.M., Theakston R.D., and Warrell D.A. Confronting the neglected problem of snake bite envenoming: the need for a global partnership. PLoS Med. 3 (2006) e150
5. Laing G.D., Harrison R.A., Theakston R.D., Renjifo J.M., Nasidi A., Gutierrez J.M., and Warrell D.A. Polyspecific snake antivenom may help in antivenom crisis. BMJ 326 (2003) 447
6. Laing G.D., Renjifo J.M., Ruiz F., Harrison R.A., Nasidi A., Gutierrez J.M., Rowley P.D., Warrell D.A., and Theakston R.D. A new Pan African polyspecific antivenom developed in response to the antivenom crisis in Africa. Toxicon 42 (2003) 35-41
7. Lalloo D.G., Trevett A.J., Saweri A., Naraqi S., Theakston R.D., and Warrell D.A. The epidemiology of snake bite in Central Province and National Capital District, Papua New Guinea. Trans. R. Soc. Trop. Med. Hyg. 89 (1995) 178-182
8. Lalloo D.G., Theakston R.D., and Warrell D.A. The African challenge. Lancet 359 (2002) 1527
9. McGain F., Limbo A., Williams D.J., Didei G., and Winkel K.D. Snakebite mortality at Port Moresby General Hospital, Papua New Guinea, 1992-2001. Med. J. Aust. 181 (2004) 687-691
10. Meyer W.P., Habib A.G., Onayade A.A., Yakubu A., Smith D.C., Nasidi A., Daudu I.J., Warrell D.A., and Theakston R.D. First clinical experiences with a new ovine Fab Echis ocellatus snake bite antivenom in Nigeria: randomized comparative trial with Institute Pasteur Serum (Ipser) Africa antivenom. Am. J. Trop. Med. Hyg. 56 (1997) 291-300
11. Nasidi, A., 2007. Snakebite as a serious public health problem for Nigeria and Africa. Presented at WHO Consultative Meeting on Rabies and Envenomings: A Neglected Public Health Issue, Geneva, Switzerland, 10 January 2007. http://www.who.int/bloodproducts/animal_sera/A.Nasidi.pdf [accessed 14 November 2007].
12. Papua New Guinea Post-Courier, 2007a. 'Caught out!', Port Moresby, 5th December 2007. http://www.postcourier.com.pg/20071205/news.htm [accessed 13 December 2007].
13. Papua New Guinea Post-Courier, 2007b. 'Snakebite serum stolen and peddled', Port Moresby, 25 June 2007. http://www.postcourier.com.pg/20070625/mohome.htm [accessed 13 December 2007].
14. Pitman C.R.S. The saw-scaled viper or carpet viper (Echis carinatus) in Africa and its bite. J. Herpetol. Ass. Afr. 9 (1973) 6-34
15. Stock R.P., Massougbodji A., Alagón A., and Chippaux J.P. Bringing antivenoms to Sub-Saharan Africa. Nat. Biotechnol. 25 (2007) 173-177
16. Theakston R.D., and Warrell D.A. Crisis in snake antivenom supply for Africa. Lancet 356 (2000) 2104
17. Theakston R.D., Warrell D.A., and Griffiths E. Report of a WHO workshop on the standardization and control of antivenoms. Toxicon 41 (2003) 541-557
18. Visser L.E., Kyei-Faried S., Belcher D.W., Geelhoed D.W., Schagen van Leeuwen J., and van Roosmalen J. Failure of a new antivenom to treat Echis ocellatus snake bite in rural Ghana: the importance of quality surveillance. Trans. R. Soc. Trop. Med. Hyg. 102 (2008) 445-450
19. Warrell D.A., and Arnett C. The importance of bites by the saw-scaled or carpet viper (Echis carinatus): epidemiological studies in Nigeria and a review of the world literature. Acta Trop. 33 (1976) 307-341
20. Warrell D.A., Davidson N.M., Ormerod L.D., Pope H.M., Watkins B.J., Greenwood B.M., and Ried H.A. Bites by the saw-scaled or carpet viper (Echis carinatus): trial of two specific antivenoms. Br. Med. J. 4 (1974) 437-440
21. Warrell D.A., Davidson N.McD., Greenwood B.M., Ormerod L.D., Pope H.M., Watkins B.J., and Prentice C.R. Poisoning by bites of the saw-scaled or carpet viper (Echis carinatus) in Nigeria. Q. J. Med. 46 (1977) 33-62
22. WHO, 2007a. Prequalification programme. A United Nations Programme managed by WHO. WHO, Geneva, Switzerland. http://www.who.int/prequal/ [accessed 14 November 2007].
23. WHO, 2007b. Rabies and Envenomings: A Neglected Public Health Issue-Consultative Meeting. WHO, Geneva, Switzerland. http://www.who.int/bloodproducts/animal_sera/rabies_envenomings/en/index.html [accessed 14 November 2007].