Sinus floor augmentation with simultaneous implant placement using Choukroun's platelet-rich fibrin as the sole grafting material: A radiologic and histologic study at 6 months

Journal of Periodontology

Volumn 80, Issue 12, 2009, Pages 2056-2064

  Mazor, Ziv ^a   Horowitz, Robert A ^b   Del Corso, Marco ^a   Prasad, Hari S ^c   Rohrer, Michael D ^c   Ehrenfest, David M Dohan ^d  

^a New York University ^*

^b NEW YORK UNIVERSITY   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Blood platelets; Bone regeneration; Dental implants; Fibrin; Maxillary sinus; Wound healing

Indexed keywords

EID: 72749109620     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2009.090252     Document Type: Article

References (45)

1. Browaeys H, Bouvry P, De Bruyn H. A literature review on biomaterials in sinus augmentation procedures. Clin Implant Dent Relat Res 2007;9:166-177.
2. Shulman LB, Jensen OT. Sinus Graft Consensus Conference. Introduction. Int J Oral Maxillofac Implants 1998;13(Suppl.):5-6.
3. Geurs NC, Wang IC, Shulman LB, Jeffcoat MK. Retrospective radiographic analysis of sinus graft and implant placement procedures from the Academy of Osseointegration Consensus Conference on Sinus Grafts. Int J Periodontics Restorative Dent 2001;21: 517-523.
4. Jensen OT, Shulman LB, Block MS, Iacono VJ. Report of the Sinus Consensus Conference of 1996. Int J Oral Maxillofac Implants 1998;13(Suppl.):11-45.
5. Wallace SS, Froum SJ. Effect of maxillary sinus augmentation on the survival of endosseous dental implants. A systematic review. Ann Periodontol 2003;8: 328-343.
6. Peleg M, Garg AK, Mazor Z. Predictability of simultaneous implant placement in the severely atrophic posterior maxilla: A 9-year longitudinal experience study of 2132 implants placed into 731 human sinus grafts. Int J Oral Maxillofac Implants 2006;21:94-102.
7. Peleg M, Mazor Z, Chaushu G, Garg AK. Sinus floor augmentation with simultaneous implant placement in the severely atrophic maxilla. J Periodontol 1998;69: 1397-1403.
8. Peleg M, Mazor Z, Garg AK. Augmentation grafting of the maxillary sinus and simultaneous implant placement in patients with 3 to 5 mm of residual alveolar bone height. Int J Oral Maxillofac Implants 1999;14: 549-556.
9. Summers RB. A new concept in maxillary implant surgery: The osteotome technique. Compendium 1994;15:152, 154-156, 158 passim; quiz 162.
10. Horowitz RA. The use of osteotomes for sinus augmentation at the time of implant placement. Compend Contin Educ Dent 1997;18:441-447, 450-442; quiz 454.
11. Nedir R, Bischof M, Vazquez L, Szmukler-Moncler S, Bernard JP. Osteotome sinus floor elevation without grafting material: A 1-year prospective pilot study with ITI implants. Clin Oral Implants Res 2006;17:679-686.
12. Fermergard R, Astrand P. Osteotome sinus floor elevation and simultaneous placement of implants-a 1-year retrospective study with Astra Tech implants. Clin Implant Dent Relat Res 2008;10:62-69.
13. Diss A, Dohan DM, Mouhyi J, Mahler P. Osteotome sinus floor elevation using Choukroun's platelet-rich fibrin as grafting material: A 1-year prospective pilot study with microthreaded implants. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:572-579.
14. Jeong SM, Choi BH, Li J, Xuan F. A retrospective study of the effects of sinus membrane elevation on bone formation around implants placed in the maxillary sinus cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;107:364-368.
15. Lundgren S, Cricchio G, Palma VC, Salata LA, Sennerby L. Sinus membrane elevation and simultaneous insertion of dental implants: A new surgical technique in maxillary sinus floor augmentation. Periodontol 2000 2008;47:193-205.
16. Thor A, Sennerby L, Hirsch JM, Rasmusson L. Bone formation at the maxillary sinus floor following simultaneous elevation of the mucosal lining and implant installation without graft material: An evaluation of 20 patients treated with 44 Astra Tech implants. J Oral Maxillofac Surg 2007;65:64-72.
17. Hatano N, Sennerby L, Lundgren S. Maxillary sinus augmentation using sinus membrane elevation and peripheral venous blood for implant-supported rehabilitation of the atrophic posterior maxilla: Case series. Clin Implant Dent Relat Res 2007;9:150-155.
18. Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: From pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol 2009;27: 158-167.
19. Choukroun J, Adda F, Schoeffler C, Vervelle A. An opportunity in perio-implantology: The PRF (in French). Implantodontie 2001;42:55-62.
20. Dohan DM, Choukroun J, Diss A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part I: Technological concepts and evolution. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e37-e44.
21. Dohan DM, Choukroun J. PRP, cPRP, PRF, PRG, PRGF, FC ⋯ How to find your way in the jungle of platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:305-306.
22. Dohan DM, Choukroun J, Diss A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part II: Platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e45-e50.
23. Dohan DM, Choukroun J, Diss A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part III: Leucocyte activation: A new feature for platelet concentrates? Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e51-e55.
24. Dohan Ehrenfest DM, Diss A, Odin G, Doglioli P, Hippolyte MP, Charrier JB. In vitro effects of Choukroun's PRF (platelet-rich fibrin) on human gingival fibroblasts, dermal prekeratinocytes, preadipocytes, and maxillofacial osteoblasts in primary cultures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009;108:341-352
25. Dohan Ehrenfest DM, de Peppo GM, Doglioli P, Sammartino G. Slow release of growth factors and thrombospondin-1 in Choukroun's platelet-rich fibrin (PRF): A gold standard to achieve for all surgical platelet concentrates technologies. Growth Factors 2009;27:63-69.
26. Soadoun AP, Touati B. Soft tissue recession around implants: Is it still unavoidable? - Part II. Pract Proced Aesthet Dent 2007;19:81-87, quiz 88.
27. Choukroun J, Diss A, Simonpieri A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part IV: Clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:e56-e60.
28. Choukroun J, Diss A, Simonpieri A, et al. Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part V: Histologic evaluations of PRF effects on bone allograft maturation in sinus lift. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:299-303.
29. Charrier JB, Monteil JP, Albert S, Collon S, Bobin S, Dohan Ehrenfest DM. Relevance of Choukroun's platelet-rich fibrin(PRF) and SMAS flap in primary reconstruction after superficial or subtotal parotidectomy in patients with focal pleiomorphic adenoma: A new technique. Rev Laryngol Otol Rhinol (Bord) 2008;129:313-318.
30. Choukroun JI, Braccini F, Diss A, Giordano G, Doglioli P, Dohan DM. Influence of platelet rich fibrin (PRF) on proliferation of human preadipocytes and tympanic keratinocytes: A new opportunity in facial lipostructure (Coleman's technique) and tympanoplasty (in French)? Rev Laryngol Otol Rhinol (Bord) 2007;128: 27-32.
31. Braccini F, Dohan DM. The relevance of Choukroun's platelet rich fibrin (PRF) during facial aesthetic lipostructure (Coleman's technique): Preliminary results (in French). Rev Laryngol Otol Rhinol (Bord) 2007;128:255-260.
32. Simonpieri A, Dohan D. The relevance of PRF during complex bimaxillary rehabilitations, using multiple bone grafts, post-avulsion implantations and immediate loading: A case report (in French). Implant 2005;11:33-47.
33. Simonpieri A, Del Corso M, Sammartino G, Dohan Ehrenfest DM. The relevance of Choukroun's plateletrich fibrin and metronidazole during complex maxillary rehabilitations using bone allograft. Part I: A new grafting protocol. Implant Dent 2009;18:102-111.
34. Simonpieri A, Del Corso M, Sammartino G, Dohan Ehrenfest DM. The relevance of Choukroun's plateletrich fibrin(PRF) and metronidazole during complex maxillary rehabilitations using bone allograft. Part II: Implant surgery, prosthodontics and survival. Implant Dent 2009;18:220-229.
35. Scharf DR, Tarnow DP. Success rates of osseointegration for implants placed under sterile versus clean conditions. J Periodontol 1993;64:954-956.
36. Dohan DM, Del Corso M, Charrier JB. Cytotoxicity analyses of Choukroun's platelet-rich fibrin (PRF) on a wide range of human cells: The answer to a commercial controversy. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:587-593.
37. Leclercq P, Zenati C,Amr S, DohanDM. Ultrasonic bone cut part 1: State-of-the-art technologies and common applications. J Oral Maxillofac Surg 2008;66:177-182. (Pubitemid 350245698)
38. Leclercq P, Zenati C, Dohan DM. Ultrasonic bone cut part 2: State-of-the-art specific clinical applications. J Oral Maxillofac Surg 2008;66:183-188. (Pubitemid 350245697)
39. Donath K, Breuner G. A method for the study of undecalcified bones and teeth with attached soft tissues. The Sage-Schliff (sawing and grinding) technique. J Oral Pathol 1982;11:318-326.
40. Rohrer MD, Schubert CC. The cutting-grinding technique for histologic preparation of undecalcified bone and bone-anchored implants. Improvements in instrumentation and procedures. Oral Surg Oral Med Oral Pathol 1992;74:73-78.
41. Misch CE, Perel ML, Wang HL, et al. Implant success, survival, and failure: The International Congress of Oral Implantologists (ICOI) Pisa Consensus Conference. Implant Dent 2008;17:5-15.
42. Sul SH, Choi BH, Li J, Jeong SM, Xuan F. Histologic changes in the maxillary sinus membrane after sinus membrane elevation and the simultaneous insertion of dental implants without the use of grafting materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:e1-e5.
43. Sul SH, Choi BH, Li J, Jeong SM, Xuan F. Effects of sinus membrane elevation on bone formation around implants placed in the maxillary sinus cavity: An experimental study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008;105:684-687.
44. van Hinsbergh VW, Collen A, Koolwijk P. Role of fibrin matrix in angiogenesis. Ann N Y Acad Sci 2001;936:426-437.
45. Clark RA. Fibrin and wound healing. Ann N Y Acad Sci 2001;936:355-367.