An Automated 1536-Well Microplate Format Cytochrome P450 Inhibition Assay Using a Tecan Freedom EVO Workstation with Integrated Innovadyne Nanodrop II Dispenser

Journal of Laboratory Automation

Volumn 15, Issue 1, 2010, Pages 58-64

  Litten, Brett A ^a   Smith, Robin ^a   Banfield, Eleanor ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

1536 well microplate; automation; cytochrome P450; drug discovery; high throughput; inhibition; Innovadyne; Nanodrop; Tecan Freedom EVO

Indexed keywords

CYTOCHROME P450; DRUG DISCOVERY; HIGH THROUGHPUT; INHIBITION; MICROPLATES;

COST REDUCTION; DISPENSERS; THROUGHPUT;

AUTOMATION;

CYTOCHROME P450; CYTOCHROME P450 1A2; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; FLUVOXAMINE MALEATE; KETOCONAZOLE; MICONAZOLE; QUINIDINE; SULFAPHENAZOLE;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG SCREENING; ENZYME INHIBITION; IC 50; LABORATORY AUTOMATION; ROBOTICS; XENOBIOTIC METABOLISM;

EID: 72649097305     PISSN: 22110682     EISSN: 15402452     Source Type: Journal    
DOI: 10.1016/j.jala.2009.08.003     Document Type: Article

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