Topical nicotinamide modulates cellular energy metabolism and provides broad-spectrum protection against ultraviolet radiation-induced immunosuppression in humans

British Journal of Dermatology

Volumn 161, Issue 6, 2009, Pages 1357-1364

  Sivapirabu, G ^a   Yiasemides, E ^a   Halliday, G M ^a   Park, J ^a   Damian, D L ^a  

^a ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Delayed type hypersensitivity; Niacin; Photoprotection; Skin cancer; Vitamin B3

Indexed keywords

NICOTINAMIDE; PROTEIN P53; SUCCINATE DEHYDROGENASE;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; CELL CULTURE; CELL METABOLISM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG MECHANISM; ENERGY METABOLISM; ERYTHEMA; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNE DEFICIENCY; IMMUNOSTIMULATION; KERATINOCYTE; MALE; METABOLIC REGULATION; NORMAL HUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; RADIATION PROTECTION; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; TUBERCULIN TEST; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION; UPREGULATION;

ADMINISTRATION, TOPICAL; ADULT; AGED; ANIMALS; APOPTOSIS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOSUPPRESSION; MALE; MICE; MIDDLE AGED; NIACINAMIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN; SKIN NEOPLASMS; SUNSCREENING AGENTS; ULTRAVIOLET RAYS; YOUNG ADULT;

EID: 72649087596     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2009.09244.x     Document Type: Article

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