Polymorphic light eruption and skin cancer prevalence: Is one protective against the other?

British Journal of Dermatology

Volumn 159, Issue 6, 2008, Pages 1342-1347

  Lembo, S ^a,b   Fallon, J ^b   O'Kelly, P ^b   Murphy, G M ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b BEAUMONT HOSPITAL   (Ireland)

Author keywords

Immunosuppression; Photosensitivity disorders; Polymorphic light eruption; Skin neoplasms; Ultraviolet radiation

Indexed keywords

SUNSCREEN;

ADOLESCENT; ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CLINICAL TRIAL; CONTROL GROUP; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; IMMUNOSURVEILLANCE; MALE; PHOTODERMATOSIS; POLYMORPHIC LIGHT ERUPTION; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTECTIVE EQUIPMENT; RADIATION EXPOSURE; RISK REDUCTION; SKIN CANCER; SKIN PROTECTION; SUN EXPOSURE; ULTRAVIOLET RADIATION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; PHOTOSENSITIVITY DISORDERS; PREVALENCE; PROSPECTIVE STUDIES; QUESTIONNAIRES; SKIN NEOPLASMS; YOUNG ADULT;

EID: 56549097314     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2008.08734.x     Document Type: Article

References (28)

1. Pao C, Norris PG, Corbett M et al. Polymorphic light eruption: prevalence in Australia and England. Br J Dermatol 1994 130 : 62 4.
2. Hasan T, Ranki A, Jansen CT et al. Disease associations in a polymorphous light eruption. A long-term follow-up study of 94 patients. Arch Dermatol 1998 134 : 1081 5.
3. McGregor JM, Grabczynska S, Vaughan R et al. Genetic modeling of abnormal photosensitivity in families with polymorphic light eruption and actinic prurigo. J Invest Dermatol 2000 115 : 471 6.
4. Epstein S. Studies in abnormal human sensitivity to light. IV. Photoallergic concept of prurigo aestivalis. J Invest Dermatol 1942 5 : 289 98.
5. Norris PG, Morris J, McGibbon DM et al. Polymorphic light eruption: an immunopathological study of evolving lesions. Br J Dermatol 1989 120 : 173 83.
6. Norris PG, Barker JN, Allen MH et al. Adhesion molecule expression in polymorphic light eruption. J Invest Dermatol 1992 99 : 504 8.
7. Fisher MS, Kripke ML. Systemic alteration induced in mice by ultraviolet light irradiation and its relationship to ultraviolet carcinogenesis. 1977. Bull World Health Organ 2002 80 : 908 12.
8. Yoshikawa T, Rae V, Bruins-Slot W et al. Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans. J Invest Dermatol 1990 95 : 530 6.
9. Weitzen ML, Bonavida B. Mechanism of inhibition of human natural killer activity by ultraviolet radiation. J Immunol 1984 133 : 3128 32.
10. Duthie MS, Kimber I, Norval M. The effect of ultraviolet radiation on the immune system. Br J Dermatol 1999 140 : 995 1009.
11. de Gruijl FR. Ultraviolet radiation and tumor immunity. Methods 2002 28 : 122 9.
12. Toews GB, Bergstresser PR, Streilein JW. Epidermal Langerhans cell density determines whether contact hypersensitivity or unresponsiveness follows skin painting with DNFB. J Immunol 1980 124 : 445 53.
13. Palmer RA, Friedmann PS. Ultraviolet radiation causes less immunosuppression in patients with polymorphic light eruption than in controls. J Invest Dermatol 2004 122 : 291 4.
14. van de Pas CB, Kelly DA, Seed PT et al. Ultraviolet-radiation-induced erythema and suppression of contact hypersensitivity responses in patients with polymorphic light eruption. J Invest Dermatol 2004 122 : 295 9.
15. Palmer RA, Hawk JL, Young AR et al. The effect of solar-simulated radiation on the elicitation phase of contact hypersensitivity does not differ between controls and patients with polymorphic light eruption. J Invest Dermatol 2005 124 : 1308 12.
16. Kölgen W, van Weelden H, den Hengst S et al. CD11b+ cells and ultraviolet-B-resistant CD1a+ cells in skin of patients with polymorphous light eruption. J Invest Dermatol 1999 113 : 4 10.
17. Murphy GM, Norris PG, Young AR et al. Low-dose ultraviolet-B irradiation depletes human epidermal Langerhans cells. Br J Dermatol 1993 129 : 674 7.
18. Schornagel IJ, Sigurdosson V, Nijhuis EHJ et al. Decreased neutrophil skin infiltration after UVB exposure in patients with polymorphous light eruption. J Invest Dermatol 2004 123 : 202 6.
19. Moloney FJ, Comber H, O'Lorcain P et al. A population-based study of skin cancer incidence and prevalence in renal transplant recipients. Br J Dermatol 2006 154 : 498 504.
20. Offringa R, Vierboom MP, van der Burg SH et al. p53: a potential target antigen for immunotherapy of cancer. Ann NY Acad Sci 2000 910 : 223 36.
21. Dumaz N, van Kranen HJ, de Vries A et al. The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice. Carcinogenesis 1997 18 : 897 904.
22. Gibson GE, Codd MB, Murphy GM. Skin type distribution and skin disease in Ireland. Ir J Med Sci 1997 166 : 72 4.
23. The National Cancer Registry Ireland. Incidence, Mortality, Treatment and Survival. 2008. Available at: http://www.ncri.ie/ncri/index.shtml (last accessed 19 May 2008).
24. Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol 1988 124 : 869 71.
25. Powels AV, Murphy GM, Rutman AJ et al. Effect of simulated sunlight on Langerhans' cells in malignant melanoma patients. Acta Derm Venereol (Stockh) 1989 69 : 482 6.
26. Cavanagh LL, Sluyter R. Epidermal Langerhans cell induction of immunity against an ultraviolet-induced skin tumor. Immunology 1996 87 : 475 80.
27. Halliday GM, Reeve VE, Barnetson RS. Langerhans cells migration into ultraviolet light-induced squamous skin tumors is unrelated to anti-tumor immunity. J Invest Dermatol 1991 97 : 830 4.
28. Moloney FJ, Almarzouqi E, O'Kelly P et al. Sunscreen use before and after transplantation and assessment of risk factors associated with skin cancer development in renal transplant recipients. Arch Dermatol 2005 141 : 978 82.