(3R,5S,7as)-(3,5-bis(4-fluorophenyl)tetrahydro-1h-oxazolo[3,4-c] oxazol-7a-yl)methanol, a novel neuroprotective agent

Journal of Medicinal Chemistry

Volumn 52, Issue 23, 2009, Pages 7537-7543

  Desino, Kelly E ^a   Ansar, Sabah ^a   Georg, Gunda I ^a   Himes, Richard H ^a   Michaelis, Mary Lou ^a   Powell, Douglas R ^a   Reiff, Emily A ^a   Telikepalli, Hanumaiah ^a   Audus, Kenneth L ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

(3,5 BIS(4 FLUOROPHENYL)TETRAHYDRO 1H OXAZOLO[3,4 C]OXAZOL 7A YL)METHANOL; AMYLOID BETA PROTEIN; HYDROGEN PEROXIDE; NEUROPROTECTIVE AGENT; OXAZOLE DERIVATIVE; PACLITAXEL; PARAQUAT; STAUROSPORINE; THAPSIGARGIN; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; EMBRYO; ENDOTHELIUM CELL; IN VITRO STUDY; MICROTUBULE; MICROTUBULE ASSEMBLY; MICROVASCULATURE; NERVE CELL; NERVE CELL NETWORK; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN BINDING; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CATTLE; CELL DEATH; CELLS, CULTURED; MICROTUBULES; NEURONS; NEUROPROTECTIVE AGENTS; OXAZOLES; PERMEABILITY; PROTEIN BINDING; PROTEIN STABILITY; RATS; RHODAMINE 123; STEREOISOMERISM;

EID: 72549088746     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900254k     Document Type: Article

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