Proteases that can distinguish among different post-translational forms of tyrosine engineered using multicolor flow cytometry

Journal of the American Chemical Society

Volumn 131, Issue 50, 2009, Pages 18186-18190

  Varadarajan, Navin ^a   Pogson, Mark ^b   Georgiou, George ^a,b   Iverson, Brent L ^b  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-NITROTYROSINE; CRITICAL STEPS; E. COLI; HIGH THROUGHPUT SCREENING; MULTI-COLOR ASSAY; MUTANT LIBRARIES; PHOSPHOTYROSINE; POST-TRANSLATIONAL MODIFICATIONS; SUBSTRATE SPECIFICITY;

AMINES; AMINO ACIDS; ENZYME ACTIVITY; ENZYMES; ESCHERICHIA COLI; FLOW CYTOMETRY; LIBRARIES; PEPTIDES; THROUGHPUT; TRANSPORT PROPERTIES;

SUBSTRATES;

3 NITROTYROSINE; ENZYME VARIANT; OMPT PROTEIN; OUTER MEMBRANE PROTEIN; PEPTIDE LIBRARY; PHOSPHOSERINE; PHOSPHOTYROSINE; PROTEINASE; SULFOTYROSINE; TYROSINE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ISOLATION; ENZYME SPECIFICITY; ESCHERICHIA COLI; FLOW CYTOMETRY; FLUORESCENCE; HIGH THROUGHPUT SCREENING; NONHUMAN; PROTEIN ENGINEERING; PROTEIN HYDROLYSIS; PROTEIN PROCESSING; PROTEOMICS;

AMINO ACID SEQUENCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLOW CYTOMETRY; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PEPTIDE LIBRARY; PEPTIDES; PLASMIDS; PROTEIN ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 72449167941     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja907803k     Document Type: Article

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