An engineered protease that cleaves specifically after sulfated tyrosine

Angewandte Chemie - International Edition

Volumn 47, Issue 41, 2008, Pages 7861-7863

  Varadarajan, Navin ^a   Georgiou, George ^b   Iverson, Brent L ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b The University of Texas at Austin   (United States)

Author keywords

Post translational modification; Proteases; Protein engineering

Indexed keywords

AMINO ACIDS;

CATALYTIC ACTIVITIES; PEPTIDE SUBSTRATES; PHOSPHO-TYROSINE; POST-TRANSLATIONAL MODIFICATION; PROTEASES; PROTEIN ENGINEERING;

AMINES;

DRUG DERIVATIVE; OMPTIN OUTER MEMBRANE PROTEASE; PEPTIDE; SERINE PROTEINASE; TYROSINE; TYROSINE O-SULFATE; TYROSINE SULFATE;

ARTICLE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; PROTEIN ENGINEERING; PROTEIN PROCESSING;

PEPTIDES; PROTEIN ENGINEERING; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 54749158816     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200800736     Document Type: Article

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