A novel allele of myosin VIIa reveals a critical function for the C-terminal FERM domain for melanosome transport in retinal pigment epithelial cells

Journal of Neuroscience

Volumn 29, Issue 50, 2009, Pages 15810-15818

  Schwander, Martin ^a   Lopes, Vanda ^b,c   Sczaniecka, Anna ^a   Gibbs, Daniel ^b,f   Lillo, Concepcion ^b,g   Delano, David ^d   Tarantino, Lisa M ^e   Wiltshire, Tim ^e   Williams, David S ^b,c   Müller, Ulrich ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c JULES STEIN EYE INSTITUTE   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^f SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^g UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; MYOSIN VIIA;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MATURATION; CELL TRANSPORT; COMPARATIVE STUDY; CONTROLLED STUDY; EPITHELIUM CELL; GENETIC SCREENING; HAIR CELL; HEARING IMPAIRMENT; INNER EAR; MELANOSOME; MOUSE; MUTATION; NEUROBIOLOGY; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA SPLICING; TISSUE SPECIFICITY; WILD TYPE;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; AUDITORY PERCEPTION; BIOLOGICAL TRANSPORT; CYTOSKELETAL PROTEINS; MELANOSOMES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, NEUROLOGIC MUTANTS; MOLECULAR SEQUENCE DATA; MYOSINS; PROTEIN STRUCTURE, TERTIARY; RETINAL PIGMENT EPITHELIUM; USHER SYNDROMES;

EID: 72449137658     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4876-09.2009     Document Type: Article

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