Anti-inflammatory and anti-asthmatic effects of Viola mandshurica W. Becker (VM) ethanolic (EtOH) extract on airway inflammation in a mouse model of allergic asthma

Journal of Ethnopharmacology

Volumn 127, Issue 1, 2010, Pages 159-164

  Lee, Mee Young ^a,c   Yuk, Ji Eun ^a   Kwon, Ok Kyoung ^a   Kim, Hui Seong ^a,b   Oh, Sei Ryang ^a   Lee, Hyeong Kyu ^a   Ahn, Kyung Seop ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Airway hyperresponsiveness; Asthma; Cytokine; Eosinophilia; Viola mandshurica W. Becker

Indexed keywords

ALCOHOL; ANTIASTHMATIC AGENT; ANTIINFLAMMATORY AGENT; CYTOKINE; DEXAMETHASONE; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 4; OVALBUMIN; PLACEBO; PLANT EXTRACT; UNCLASSIFIED DRUG; VIOLA MANDSHURICA EXTRACT;

ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; EOSINOPHILIA; FEMALE; HISTOPATHOLOGY; IMMUNOGLOBULIN BLOOD LEVEL; LUNG LAVAGE; MEDICINAL PLANT; MOUSE; MUCUS SECRETION; NONHUMAN; RESPIRATORY TRACT INFLAMMATION; VIOLA MANDSHURICA;

ANIMALS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASTHMA; BRONCHI; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; EOSINOPHILIA; ETHANOL; FEMALE; HYPERSENSITIVITY, DELAYED; IMMUNOGLOBULIN E; INFLAMMATION; INTERLEUKINS; KOREA; MICE; MICE, INBRED BALB C; MUCUS; OVALBUMIN; PHYTOTHERAPY; PLANT EXTRACTS; PLANTS, MEDICINAL; RANDOM ALLOCATION; VIOLA;

MUS; VIOLA MANDSHURICA;

EID: 72449130406     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.09.033     Document Type: Article

References (31)

1. Barnesn J.B. Pathophysiology of asthma. In: Barnes P.J., Rodger I.W., and Thomson N.C. (Eds). Asthma: Basic Mechanisms and Clinical Management (1998), Academic Press, London 487-506
2. Bisset L.R., and Schmid-Grendelmeier P. Chemokines and their receptors in the pathogenesis of allergic asthma: progress and perspective. Current Opinion in Pulmonary Medicine 11 (2005) 35-42
3. Brightling C.E., Symon F.A., Birring S.S., Bradding P., Pavord I.D., and Wardlaw A.J. Th2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis. The Journal of Allergy and Clinical Immunology 110 (2002) 899-905
4. Bukstein D., Kraft M., Liu A.H., and Peters S.P. Asthma end points and outcomes: what have we learned?. The Journal of Allergy and Clinical Immunology 118 (2006) S1-S15
5. Busse W.W., and Lemanske Jr. R.F. Asthma. The New England Journal of Medicine 344 (2001) 350-362
6. Collins P.D., Marleau S., Griffiths-Johnson D.A., Jose P.J., and Williams T.J. Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo. The Journal of Experimental Medicine 182 (1995) 1169-1174
7. Daigle I., and Simon H.U. Alternative functions for TRAIL receptors in eosinophils and neutrophils. Swiss Medical Weekly 131 (2001) 231-237
8. Djukanovic R., Roche W.R., Wilson J.W., Beasley C.R., Twentyman O.P., Howarth R.H., and Holgate S.T. Mucosal inflammation in asthma. The American Review of Respiratory Disease 142 (1990) 434-457
9. Elias J.A., Lee C.G., Zheng T., Ma B., Homer R.J., and Zhu Z. New insights into the pathogenesis of asthma. The Journal of Clinical Investigation 111 (2003) 291-297
10. Farahi N., Cowburn A.S., Upton P.D., Deighton J., Sobolewski A., Gherardi E., Morrell N.W., and Chilvers E.R. Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells. Journal of Immunology 179 (2007) 1264-1273
11. Fish S.C., Donaldson D.D., Goldman S.J., Williams C.M., and Kasaian M.T. IgE generation and mast cell effector function in mice deficient in IL-4 and IL-13. Journal of Immunology 74 (2005) 7716-7724
12. Fujisawa T., Kato Y., Nagase H., Atsuta J., Terada A., Iguchi K., Kamiya H., Morita Y., Kitaura M., Kawasaki H., Yoshie O., and Hirai K. Chemokines induce eosinophil degranulation through CCR-3. The Journal of Allergy and Clinical Immunology 106 (2000) 507-513
13. Herrick C.A., and Bottomly K. To respond or not to respond: T cells in allergic asthma. Nature Reviews Immunology 3 (2003) 405-412
14. Hoshino M., Nakamura Y., Sim J., Shimojo J., and Isogai S. Bronchial subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation. The Journal of Allergy and Clinical Immunology 102 (1998) 783-788
15. Issekutz A.C., and Sapru K. Modulation of adjuvant arthritis in the rat by 2-methoxyestradiol: an effect independent of anti-angiogenic action. International Immunopharmacology 8 (2008) 708-716
16. Lee B.W., and Kim D.H. Inhibitory effect of Violae herba extract on inflammatory cytokine production by IL-1β and TNF-α in cultured human synovial cells. The Korean Journal of Hepatology 18 (2003) 89-96
17. Leroy B., Falmagne P., and Wattiez R. Sample preparation of bronchoalveolar lavage fluid. Methods in Molecular Biology 425 (2008) 67-75
18. Lewis J.A., Rao K.M.K., Castranova V., Vallyathan V., Dennis W.E., and Knechtges P.L. Proteomic analysis of bronchoalveolar lavage fluid: effect of acute exposure to diesel exhaust particles in rats. Environmental Health Perspectives 115 (2007) 756-763
19. Lukacs N.W. Role of chemokines in the pathogenesis of asthma. Nature Reviews Immunology 1 (2001) 108-116
20. Mosmann T.R., and Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunology Today 17 (1996) 138-146
21. Mosmann T.R., Cherwinski H., Bond M.W., Gieldin M.A., and Coffman R.L. Two types of murine T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. Journal of Immunology 136 (1986) 2348-2357
22. Myou S., Leff A.R., You S., Boetticher E., Tong J., Meliton A.Y., Liu J., Munoz N.M., and Ahu X. Blockade of inflammation and airway hyperresponsiveness in immune-sensitized mice by dominant-negative phosphoinositide 3-kinase-TAT. The Journal of Experimental Medicine 198 (2003) 1573-1582
23. Ngoc L.P., Gold D.R., Tzianabos A.O., Weiss S.T., and Celedon J.C. Cytokines, allergy, and asthma. Current Opinion in Allergy and Clinical Immunology 5 (2005) 161-166
24. Pounds J.G., Flora J.W., Adkins J.N., Lee K.M., Rana G.S.J.B., Sengupta T., Smith R.D., and McKinney W.J. Characterization of the mouse bronchoalveolar lavage proteome by micro-capillary LC-FTICR mass spectrometry. Journal of Chromatography 864 (2008) 95-101
25. Sanderson C.J. Interleukin-5: an eosinophil growth and activation factor. Developments in Biological Standardization 69 (1988) 23-29
26. Sanderson C.J. Interleukin-5, eosinophils, and disease. Blood 79 (1992) 3101-3109
27. Shimizu T., Shimizu S., Hattori R., and Majima Y. A mechanism of antigen-induced goblet cell degranulation in the nasal epithelium of sensitized rats. The Journal of Allergy and Clinical Immunology 112 (2003) 119-125
28. Wardlaw S., Dunnette G.J., Gleich J.V., Collins A.B., and Kay. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. The American Review of Respiratory Disease 137 (1988) 62-69
29. Wills-Karp. Interleukin-13 in asthma pathogenesis. Immunological Reviews 202 (2004) 175-190
30. Yamaguchi Y., Suda T., Suda J., Eguchi M., Miura Y., Harada N., Tominaga A., and Takatu K. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. The Journal of Experimental Medicine 167 (1988) 43-56
31. Yook C.S., Lee W.C., and Moon C.K. Studies on flavonoid glycoside of the leaves of Viola diamantica. Hankok YoungyangYakHak Hoeji 33 (1989) 124-128