Measuring Progression of Coronary Atherosclerosis with Computed Tomography: Searching for Clarity Among Shades of Gray

Journal of Cardiovascular Computed Tomography

Volumn 3, Issue SUPPL.2, 2009, Pages

  Priester, Tiffany C ^a   Litwin, Sheldon E ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

Atherosclerosis; Cardiovascular computed tomography; Coronary artery disease; Plaque

Indexed keywords

ALENDRONIC ACID; ALPHA TOCOPHEROL; AMILORIDE PLUS HYDROCHLOROTHIAZIDE; ASCORBIC ACID; ATORVASTATIN; CERIVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NICOTINIC ACID; NIFEDIPINE; PRAVASTATIN; SIMVASTATIN; VITAMIN B GROUP;

ARTERY CALCIFICATION; ATHEROSCLEROTIC PLAQUE; CALCIFICATION; CARDIOVASCULAR RISK; CLINICAL ASSESSMENT; CLINICAL TRIAL; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; CORONARY RISK; DISEASE COURSE; DRUG MEGADOSE; HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REMISSION; REVIEW; SCORING SYSTEM;

ALGORITHMS; CALCINOSIS; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; HUMANS; RADIOGRAPHIC IMAGE ENHANCEMENT; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 72249121502     PISSN: 19345925     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jcct.2009.10.011     Document Type: Review

References (57)

1. Rumberger J.A. The promise of quantitative computed tomography coronary angiography and noninvasive segmental coronary plaque quantification: pushing the "edge". J Am Coll Cardiol 47 (2006) 678-680
2. Leber A.W., Knez A., von Ziegler F., Becker A., Nikolaou K., Paul S., Wintersperger B., Reiser M., Becker C.R., Steinbeck G., and Boekstegers P. Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography: a comparative study with quantitative coronary angiography and intravascular ultrasound. J Am Coll Cardiol 46 (2005) 147-154
3. Budoff M.J., Shaw L.J., Liu S.T., Weinstein S.R., Mosler T.P., Tseng P.H., Flores F.R., Callister T.Q., Raggi P., and Berman D.S. Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients. J Am Coll Cardiol 49 (2007) 1860-1870
4. Mintz G.S., Pichard A.D., Popma J.J., Kent K.M., Satler L.F., Bucher T.A., and Leon M.B. Determinants and correlates of target lesion calcium in coronary artery disease: a clinical, angiographic and intravascular ultrasound study. J Am Coll Cardiol 29 (1997) 268-274
5. Budoff M.J., and Gul K.M. Expert review on coronary calcium. Vasc Health Risk Manag 4 (2008) 315-324
6. Naghavi M., Falk E., Hecht H.S., Jamieson M.J., Kaul S., Berman D., Fayad Z., Budoff M.J., Rumberger J., Naqvi T.Z., Shaw L.J., Faergeman O., Cohn J., Bahr R., Koenig W., Demirovic J., Arking D., Herrera V.L., Badimon J., Goldstein J.A., Rudy Y., Airaksinen J., Schwartz R.S., Riley W.A., Mendes R.A., Douglas P., and Shah P.K. From vulnerable plaque to vulnerable patient-Part III: Executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report. Am J Cardiol 98 (2006) 2H-15H
7. Arad Y., Goodman K.J., Roth M., Newstein D., and Guerci A.D. Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: the St. Francis Heart Study. J Am Coll Cardiol 46 (2005) 158-165
8. Sangiorgi G., Rumberger J.A., Severson A., Edwards W.D., Gregoire J., Fitzpatrick L.A., and Schwartz R.S. Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology. J Am Coll Cardiol 31 (1998) 126-133
9. Gopal A., Nasir K., Ahmadi N., Gul K., Tiano J., Flores M., Young E., Witteman A.M., Holland T.C., Flores F., Mao S.S., and Budoff M.J. Cardiac computed tomographic angiography in an outpatient setting: an analysis of clinical outcomes over a 40-month period. J Cardiovasc Comput Tomogr 3 (2009) 90-95
10. Min J.K., Shaw L.J., Devereux R.B., Okin P.M., Weinsaft J.W., Russo D.J., Lippolis N.J., Berman D.S., and Callister T.Q. Prognostic value of multidetector coronary computed tomographic angiography for prediction of all-cause mortality. J Am Coll Cardiol 50 (2007) 1161-1170
11. Agatston A.S., Janowitz W.R., Hildner F.J., Zusmer N.R., Viamonte Jr. M., and Detrano R. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol 15 (1990) 827-832
12. Yoon H.C., Greaser III L.E., Mather R., Sinha S., McNitt-Gray M.F., and Goldin J.G. Coronary artery calcium: alternate methods for accurate and reproducible quantitation. Acad Radiol 4 (1997) 666-673
13. Callister T.Q., Cooil B., Raya S.P., Lippolis N.J., Russo D.J., and Raggi P. Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method. Radiology 208 (1998) 807-814
14. Schmermund A., Baumgart D., Mohlenkamp S., Kriener P., Pump H., Gronemeyer D., Seibel R., and Erbel R. Natural history and topographic pattern of progression of coronary calcification in symptomatic patients: An electron-beam CT study. Arterioscler Thromb Vasc Biol 21 (2001) 421-426
15. Mowatt G., Cummins E., Waugh N., Walker S., Cook J., Jia X., Hillis G.S., and Fraser C. Systematic review of the clinical effectiveness and cost-effectiveness of 64-slice or higher computed tomography angiography as an alternative to invasive coronary angiography in the investigation of coronary artery disease. Health Technol Assess 12 (2008) iii-iv, ix-143
16. Leber A.W., Becker A., Knez A., von Ziegler F., Sirol M., Nikolaou K., Ohnesorge B., Fayad Z.A., Becker C.R., Reiser M., Steinbeck G., and Boekstegers P. Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system: a comparative study using intravascular ultrasound. J Am Coll Cardiol 47 (2006) 672-677
17. Greenland P., Bonow R.O., Brundage B.H., Budoff M.J., Eisenberg M.J., Grundy S.M., Lauer M.S., Post W.S., Raggi P., Redberg R.F., Rodgers G.P., Shaw L.J., Taylor A.J., and Weintraub W.S. ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation Clinical Expert Consensus Task Force (ACCF/AHA Writing Committee to Update the 2000 Expert Consensus Document on Electron Beam Computed Tomography) developed in collaboration with the Society of Atherosclerosis Imaging and Prevention and the Society of Cardiovascular Computed Tomography. J Am Coll Cardiol 49 (2007) 378-402
18. Budoff M.J., Achenbach S., Blumenthal R.S., Carr J.J., Goldin J.G., Greenland P., Guerci A.D., Lima J.A., Rader D.J., Rubin G.D., Shaw L.J., and Wiegers S.E. Assessment of coronary artery disease by cardiac computed tomography: a scientific statement from the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical Cardiology. Circulation 114 (2006) 1761-1791
19. Matthews K.A., Kuller L.H., Chang Y., and Edmundowicz D. Premenopausal risk factors for coronary and aortic calcification: a 20-year follow-up in the healthy women study. Prev Med 45 (2007) 302-308
20. Yoon H.C., Emerick A.M., Hill J.A., Gjertson D.W., and Goldin J.G. Calcium begets calcium: progression of coronary artery calcification in asymptomatic subjects. Radiology 224 (2002) 236-241
21. Sutton-Tyrrell K., Kuller L.H., Edmundowicz D., Feldman A., Holubkov R., Givens L., and Matthews K.A. Usefulness of electron beam tomography to detect progression of coronary and aortic calcium in middle-aged women. Am J Cardiol 87 (2001) 560-564
22. Bielak L.F., Sheedy II P.F., and Peyser P.A. Coronary artery calcification measured at electron-beam CT: agreement in dual scan runs and change over time. Radiology 218 (2001) 224-229
23. Shemesh J., Tenenbaum A., Stroh C.I., Apter S., Har-Zahav Y., Fisman E.Z., Itzchak Y., and Motro M. Double-helical CT as a new tool for tracking of allograft atherosclerosis in heart transplant recipients. Invest Radiol 34 (1999) 485-488
24. Ammirati A.L., Dalboni M.A., Cendoroglo M., Draibe S.A., Santos R.D., Miname M., and Canziani M.E. The progression and impact of vascular calcification in peritoneal dialysis patients. Perit Dial Int 27 (2007) 340-346
25. Hsia J., Klouj A., Prasad A., Burt J., Adams-Campbell L.L., and Howard B.V. Progression of coronary calcification in healthy postmenopausal women. BMC Cardiovasc Disord (2004) 421
26. Braun J., Oldendorf M., Moshage W., Heidler R., Zeitler E., and Luft F.C. Electron beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients. Am J Kidney Dis 27 (1996) 394-401
27. Maahs D.M., Ogden L.G., Kretowski A., Snell-Bergeon J.K., Kinney G.L., Berl T., and Rewers M. Serum cystatin C predicts progression of subclinical coronary atherosclerosis in individuals with type 1 diabetes. Diabetes 56 (2007) 2774-2779
28. Bursztyn M., Motro M., Grossman E., and Shemesh J. Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation. J Hypertens 21 (2003) 1953-1959
29. Shemesh J., Apter S., Stolero D., Itzchak Y., and Motro M. Annual progression of coronary artery calcium by spiral computed tomography in hypertensive patients without myocardial ischemia but with prominent atherosclerotic risk factors, in patients with previous angina pectoris or healed acute myocardial infarction, and in patients with coronary events during follow-up. Am J Cardiol 87 (2001) 1395-1397
30. Kronmal R.A., McClelland R.L., Detrano R., Shea S., Lima J.A., Cushman M., Bild D.E., and Burke G.L. Risk factors for the progression of coronary artery calcification in asymptomatic subjects: results from the Multi-Ethnic Study of Atherosclerosis (MESA). Circulation 115 (2007) 2722-2730
31. Cassidy A.E., Bielak L.F., Zhou Y., Sheedy II P.F., Turner S.T., Breen J.F., Araoz P.A., Kullo I.J., Lin X., and Peyser P.A. Progression of subclinical coronary atherosclerosis: does obesity make a difference?. Circulation 111 (2005) 1877-1882
32. Wong N.D., Kawakubo M., LaBree L., Azen S.P., Xiang M., and Detrano R. Relation of coronary calcium progression and control of lipids according to National Cholesterol Education Program guidelines. Am J Cardiol 94 (2004) 431-436
33. Raggi P., Callister T.Q., and Shaw L.J. Progression of coronary artery calcium and risk of first myocardial infarction in patients receiving cholesterol-lowering therapy. Arterioscler Thromb Vasc Biol 24 (2004) 1272-1277
34. Hodis H.N., Mack W.J., Dustin L., Mahrer P.R., Azen S.P., Detrano R., Selhub J., Alaupovic P., Liu C.R., Liu C.H., Hwang J., Wilcox A.G., and Selzer R.H. High-dose B vitamin supplementation and progression of subclinical atherosclerosis: a randomized controlled trial. Stroke 40 (2009) 730-736
35. Hill J.A., Goldin J.G., Gjertson D., Emerick A.M., Greaser L.D., Yoon H.C., Khorrami S., Aziz D., and Adams J.S. Progression of coronary artery calcification in patients taking alendronate for osteoporosis. Acad Radiol 9 (2002) 1148-1152
36. Callister T.Q., Raggi P., Cooil B., Lippolis N.J., and Russo D.J. Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. N Engl J Med 339 (1998) 1972-1978
37. Budoff M.J., Chen G.P., Hunter C.J., Takasu J., Agrawal N., Sorochinsky B., and Mao S. Effects of hormone replacement on progression of coronary calcium as measured by electron beam tomography. J Womens Health (Larchmt) 14 (2005) 410-417
38. Raggi P., Davidson M., Callister T.Q., Welty F.K., Bachmann G.A., Hecht H., and Rumberger J.A. Aggressive versus moderate lipid-lowering therapy in hypercholesterolemic postmenopausal women: Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES). Circulation 112 (2005) 563-571
39. Terry J.G., Carr J.J., Kouba E.O., Davis D.H., Menon L., Bender K., Chandler E.T., Morgan T., and Crouse III J.R. Effect of simvastatin (80 mg) on coronary and abdominal aortic arterial calcium (from the coronary artery calcification treatment with zocor [CATZ] study). Am J Cardiol 99 (2007) 1714-1717
40. Schmermund A., Achenbach S., Budde T., Buziashvili Y., Forster A., Friedrich G., Henein M., Kerkhoff G., Knollmann F., Kukharchuk V., Lahiri A., Leischik R., Moshage W., Schartl M., Siffert W., Steinhagen-Thiessen E., Sinitsyn V., Vogt A., Wiedeking B., and Erbel R. Effect of intensive versus standard lipid-lowering treatment with atorvastatin on the progression of calcified coronary atherosclerosis over 12 months: a multicenter, randomized, double-blind trial. Circulation 113 (2006) 427-437
41. Hecht H.S., and Harman S.M. Relation of aggressiveness of lipid-lowering treatment to changes in calcified plaque burden by electron beam tomography. Am J Cardiol 92 (2003) 334-336
42. Achenbach S., Ropers D., Pohle K., Leber A., Thilo C., Knez A., Menendez T., Maeffert R., Kusus M., Regenfus M., Bickel A., Haberl R., Steinbeck G., Moshage W., and Daniel W.G. Influence of lipid-lowering therapy on the progression of coronary artery calcification: a prospective evaluation. Circulation 106 (2002) 1077-1082
43. Motro M., and Shemesh J. Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics. Hypertension 37 (2001) 1410-1413
44. Budoff M.J., Lane K.L., Bakhsheshi H., Mao S., Grassmann B.O., Friedman B.C., and Brundage B.H. Rates of progression of coronary calcium by electron beam tomography. Am J Cardiol 86 (2000) 8-11
45. Hoffmann U., Derfler K., Haas M., Stadler A., Brady T.J., and Kostner K. Effects of combined low-density lipoprotein apheresis and aggressive statin therapy on coronary calcified plaque as measured by computed tomography. Am J Cardiol 91 (2003) 461-464
46. Budoff M.J., and Raggi P. Coronary artery disease progression assessed by electron-beam computed tomography. Am J Cardiol 88 (2001) 46E-50E
47. Horiguchi J., Yamamoto H., Hirai N., Akiyama Y., Fujioka C., Marukawa K., Fukuda H., and Ito K. Variability of repeated coronary artery calcium measurements on low-dose ECG-gated 16-MDCT. AJR Am J Roentgenol 187 (2006) W1-W6
48. McCullough P.A. Effect of lipid modification on progression of coronary calcification. J Am Soc Nephrol 16 Suppl (2005) 2S115-9
49. Arad Y., Spadaro L.A., Roth M., Newstein D., and Guerci A.D. Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial. J Am Coll Cardiol 46 (2005) 166-172
50. Priester T., Ault T.G., Adams T.D., Hunt S.C., and Litwin S.E. Coronary Calcium Scores Are Lower 5 Years After Bariatric Surgery: Evidence for Slowed Progression of Atherosclerosis?. Circulation 120 (2009) S341-S342
51. Naghavi M., Libby P., Falk E., Casscells S.W., Litovsky S., Rumberger J., Badimon J.J., Stefanadis C., Moreno P., Pasterkamp G., Fayad Z., Stone P.H., Waxman S., Raggi P., Madjid M., Zarrabi A., Burke A., Yuan C., Fitzgerald P.J., Siscovick D.S., de Korte C.L., Aikawa M., Juhani Airaksinen K.E., Assmann G., Becker C.R., Chesebro J.H., Farb A., Galis Z.S., Jackson C., Jang I.K., Koenig W., Lodder R.A., March K., Demirovic J., Navab M., Priori S.G., Rekhter M.D., Bahr R., Grundy S.M., Mehran R., Colombo A., Boerwinkle E., Ballantyne C., Insull Jr. W., Schwartz R.S., Vogel R., Serruys P.W., Hansson G.K., Faxon D.P., Kaul S., Drexler H., Greenland P., Muller J.E., Virmani R., Ridker P.M., Zipes D.P., Shah P.K., and Willerson J.T. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation 108 (2003) 1664-1672
52. Uehara M., Funabashi N., Mikami Y., Shiina Y., Nakamura K., and Komuro I. Quantitative effect of Atorvastatin on size and content of non-calcified plaques of coronary arteries 1 year after Atorvastatin treatment by multislice computed tomography. Int J Cardiol 130 (2008) 269-275
53. Achenbach S., Moselewski F., Ropers D., Ferencik M., Hoffmann U., MacNeill B., Pohle K., Baum U., Anders K., Jang I.K., Daniel W.G., and Brady T.J. Detection of calcified and noncalcified coronary atherosclerotic plaque by contrast-enhanced, submillimeter multidetector spiral computed tomography: a segment-based comparison with intravascular ultrasound. Circulation 109 (2004) 14-17
54. Cordeiro M.A., and Lima J.A. Atherosclerotic plaque characterization by multidetector row computed tomography angiography. J Am Coll Cardiol 47 8 Suppl (2006) C40-C47
55. Schaap M., Metz C.T., Walsum T., Giessen A., Weustink A.C., Mollet N.R., Bauer C., Bogunovic H., Castro C., Deng X., Dikici E., O'Donnell T., Frenay M., Friman O., Hoyos M.H., Kitslaar P.H., Krissian K., Kühnel C., Luengo-Oroz M.A., Orkisz M., Smedby O., Styner M., Szymczak A., Tek H., Wang C., Warfield S.K., Zambal S., Zhang Y., Krestin G.P., and Niessena W.J. Standardized evaluation methodology and reference database for evaluating coronary artery centerline extraction algorithms. Med Image Anal 13 (2009) 701-714
56. Shemesh J., Apter S., Stroh C.I., Itzchak Y., and Motro M. Tracking coronary calcification by using dual-section spiral CT: a 3-year follow-up. Radiology 217 (2000) 461-465
57. Navaneethan S.D., Nigwekar S.U., Perkovic V., Johnson D.W., Craig J.C., and Strippoli G.F. HMG CoA reductase inhibitors (statins) for dialysis patients. Cochrane Database Syst Rev (2009) CD004289