Solvent-free, microwave assisted synthesis of polyhalo heterocyclic ketene aminals as novel anti-cancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 1, 2010, Pages 48-51

  Yan, Sheng Jiao ^a   Huang, Chao ^a   Zeng, Xiang Hui ^a   Huang, Rong ^a   Lin, Jun ^a  

^a YUNNAN UNIVERSITY   (China)

Author keywords

C Arylation; Microwave assisted synthesis; Polyhalo heterocyclic ketene aminals; Solvent free

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; HETEROCYCLIC COMPOUND; KETENE DERIVATIVE; POLYHALO DERIVATIVE; POLYHALO HETEROCYCLIC KETENE AMINAL DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; MICROWAVE IRRADIATION; SUBSTITUTION REACTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; ETHYLENES; HETEROCYCLIC COMPOUNDS; HUMANS; IMIDAZOLIDINES; KETONES; MICROWAVES; NITRILES; STRUCTURE-ACTIVITY RELATIONSHIP;

TRIFLUORO;

EID: 72149129506     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.11.044     Document Type: Article

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