The repair of large segmental bone defects in the rabbit with vascularized tissue engineered bone

Biomaterials

Volumn 31, Issue 6, 2010, Pages 1171-1179

  Zhou, Jian ^a   Lin, Hong ^a   Fang, Taolin ^a   Li, Xilei ^a   Dai, Wenda ^a   Uemura, Toshimasa ^b   Dong, Jian ^a  

^a FUDAN UNIVERSITY   (China)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Bone repair; Bone tissue engineering; Endothelial cells; Mesenchymal stem cells; Vascularization

Indexed keywords

BIOMECHANICAL TESTS; BONE DEFECT; BONE REPAIR; BONE TISSUE ENGINEERING; CLINICAL SETTINGS; COCULTURE; HISTOLOGIC ANALYSIS; MESENCHYMAL STEM CELL; OSTEOGENESIS; SEGMENTAL BONE DEFECT; TRI-CALCIUM PHOSPHATES; VASCULARIZATION; VASCULARIZED TISSUES;

BIOMECHANICS; BLOOD VESSEL PROSTHESES; BONE; CELL CULTURE; COMPUTERIZED TOMOGRAPHY; DEFECTS; FLOWCHARTING; MECHANICAL PROPERTIES; REPAIR; SELF ASSEMBLY; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; TISSUE ENGINEERING; TRANSMISSION CONTROL PROTOCOL;

ENDOTHELIAL CELLS;

CALCIUM PHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE DEFECT; BONE DEVELOPMENT; BONE RADIOGRAPHY; BONE REMODELING; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; HISTOPATHOLOGY; MESENCHYMAL STEM CELL; NONHUMAN; POROSITY; PRIORITY JOURNAL; RABBIT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TISSUE ENGINEERING; ULNA; VASCULARIZATION;

ANIMALS; BONE TRANSPLANTATION; CELL CULTURE TECHNIQUES; CELLS, CULTURED; COMBINED MODALITY THERAPY; ILIUM; MESENCHYMAL STEM CELL TRANSPLANTATION; RABBITS; TISSUE ENGINEERING; TREATMENT OUTCOME; ULNA FRACTURES;

ORYCTOLAGUS CUNICULUS;

EID: 72149127644     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.10.043     Document Type: Article

References (26)

1. Cancedda R., Giannoni P., and Mastrogiacomo M. A tissue engineering approach to bone repair in large animal models and in clinical practice. Biomaterials 28 (2007) 4240-4250
2. Weng Y.L., Wang M., Liu W., Hu X.J., Chai G., Yan Q.M., et al. Repair of experimental alveolar bone defects by tissue-engineered bone. Tissue Engineering 12 6 (2006) 1503-1513
3. Viateau V., Guillemin G., Bousson V., Oudina K., Hannouche D., Sedel L., et al. Long-bone critical-size defects treated with tissue-engineered grafts: a study on sheep. Journal of Orthopaedic Research 25 6 (2007) 741-749
4. Nakasa T., Ishida O., Sunagawa T., Nakamae A., Yasunaga Y., Agung M., et al. Prefabrication of vascularized bone graft using a combination of fibroblast growth factor-2 and vascular bundle implantation into a novel interconnected porous calcium hydroxyapatite ceramic. Journal of Biomedical Materials Research Part A 75A 2 (2005) 350-355
5. Kawamura K., Yajima H., Ohgushi H., Tomita Y., Kobata Y., Shigematsu K., et al. Experimental study of vascularized tissue-engineered bone grafts. Plastic and Reconstructive Surgery 117 5 (2006) 1471-1479
6. Rouwkema J., Rivron N.C., and van Blitterswijk C.A. Vascularization in tissue engineering. Trends in Biotechnology 26 8 (2008) 434-441
7. Kneser U., Schaefer D.J., Polykandriotis E., and Horch R.E. Tissue engineering of bone: the reconstructive surgeon's point of view. Journal of Cellular and Molecular Medicine 10 1 (2006) 7-19
8. Fuchs S., Hermanns M.I., and Kirkpatrick C.J. Retention of a differentiated endothelial phenotype by outgrowth endothelial cells isolated from human peripheral blood and expanded in long-term cultures. Cell and Tissue Research 326 1 (2006) 79-92
9. Oswald J., Boxberger S., Jorgensen B., Feldmann S., Ehninger G., Bornhauser M., et al. Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22 3 (2004) 377-384
10. Dai W.D., Dong J., Fang T.L., and Uemura T. Stimulation of osteogenic activity in mesenchymal stem cells by FK506. Journal of Biomedical Materials Research Part A 86 1 (2008) 235-243
11. Dong J., Uemura T., Kikuchi M., Tanaka J., and Tateishi T. Long-term durability of porous hydroxyapatite with low-pressure system to support osteogenesis of mesenchymal stem cells. Bio-Medical Materials and Engineering 12 2 (2002) 203-209
12. Kokubo S., Fujimoto R., Yokota S., Fukushima S., Nozaki K., Takahashi K., et al. Bone regeneration by recombinant human bone morphogenetic protein-2 and a novel biodegradable carrier in rabbit ulnar defect model. Biomaterials 24 (2003) 1643-1651
13. Kokubo S., Nozaki K., Fukushima S., Takahashi K., Miyata K., Fujimoto R., et al. Recombinant human bone morphogenetic protein-2 as an osteoinductive biomaterial and a biodegradable carrier in a rabbit ulnar defect model. Journal of Bioactive and Compatible Polymers 23 (2008) 348-366
14. Lane J.M., and Sandhu H.S. Current approaches to experimental bone grafting. Orthopedic Clinics of North America 18 2 (1987) 213-225
15. Bouletreau P.J., Warren S.M., Spector J.A., Peled Z.M., Gerrets R.P., Greenwald J.A., et al. Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing. Plastic and Reconstructive Surgery 109 7 (2002) 2384-2397
16. Lammert E., Cleaver O., and Melton D. Induction of pancreatic differentiation by signals from blood vessels. Science 294 5542 (2001) 564-567
17. Villars F., Bordenave L., Bareille R., and Amedee J. Effect of human endothelial cells on human bone marrow stromal cell phenotype: role of VEGF?. Journal of Cellular Biochemistry 79 4 (2000) 672-685
18. Murohara T. Therapeutic vasculogenesis using human cord blood-derived endothelial progenitors. Trends in Cardiovascular Medicine 11 8 (2001) 303-307
19. Usami K., Mizuno H., Okada K., Narita Y., Aoki M., Kondo T., et al. Composite implantation of mesenchymal stem cells with endothelial progenitor cells enhances tissue-engineered bone formation. Journal of Biomedical Materials Research Part A 90A 3 (2009) 730-741
20. Yu H.Y., VandeVord P.J., Mao L., Matthew H.W., Wooley P.H., and Yang S.Y. Improved tissue-engineered bone regeneration by endothelial cell mediated vascularization. Biomaterials 30 (2009) 508-517
21. Karageorgiou V., and Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 26 (2005) 5474-5491
22. Schimming R., Juengling F.D., Lauer G., and Schmelzeisen R. Evaluation of microvascular bone graft reconstruction of the head and neck with 3-D Tc-99m-DPD SPECT scans. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics 90 6 (2000) 679-685
23. Ryan P.J., and Fogelman I. The bone scan: where are we now?. Seminars in Nuclear Medicine 25 2 (1995) 76-91
24. 99mTc-diphosphonate scintigraphy of revascularized iliac crest flaps. Journal of Oral and Maxillofacial Surgery 25 (1996) 366-369
25. Chang C.S., Su C.Y., and Lin T.C. Scanning electron microscopy observation of vascularization around hydroxyapatite using vascular corrosion casts. Journal of Biomedical Materials Research 48 4 (1999) 411-416
26. Deckers M.M.L., van Bezooijen R.L., van der Horst G., Hoogendam J., van der Bent C., Papapoulos S.E., et al. Bone morphogenetic proteins stimulate angiogenesis through osteoblast-derived vascular endothelial growth factor A. Endocrinology 143 4 (2002) 1545-1553