Bone regeneration by recombinant human bone morphogenetic protein-2 and a novel biodegradable carrier in a rabbit ulnar defect model

Biomaterials

Volumn 24, Issue 9, 2003, Pages 1643-1651

  Kokubo, Satoshi ^a   Fujimoto, Ryuhei ^b   Yokota, Shoji ^a   Fukushima, Shinji ^a   Nozaki, Kazutoshi ^a   Takahashi, Koichiro ^a   Miyata, Keiji ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

Author keywords

Gelatin sponge; PLGA; Rabbit; rhBMP 2; Segmental bone defect

Indexed keywords

BIOMECHANICS; HISTOLOGY; IMPLANTS (SURGICAL); PROTEINS; RADIOGRAPHY;

BONE REGENERATION;

BONE;

DRUG CARRIER; GELATIN SPONGE; POLYGLACTIN; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; BIOMECHANICS; BONE DEFECT; BONE REGENERATION; BONE REMODELING; CONTROLLED STUDY; DIAPHYSIS; DOSE RESPONSE; FRACTURE HEALING; HISTOLOGY; IMPLANT; IMPLANTATION; LAMELLAR BODY; MALE; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RABBIT; RADIOGRAPHY; SOFT TISSUE DEFECT; TREATMENT OUTCOME; ULNA;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; GELATIN; HUMANS; LACTIC ACID; POLYGLYCOLIC ACID; POLYMERS; RABBITS; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA; ULNA;

ORYCTOLAGUS CUNICULUS;

EID: 0346736496     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(02)00551-3     Document Type: Article

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